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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 510.190.150
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 1.3572E-10 4 23 4 6292
Sin3 complex 3.8553E-10 4 4 3 6292
Sin3-type complex 9.6371E-10 4 5 3 6292
chromatin remodeling complex 5.7698E-8 4 99 4 6292
nucleoplasm part 2.2451E-6 4 245 4 6292
nucleoplasm 3.0322E-6 4 264 4 6292
nuclear chromatin 5.9453E-6 4 73 3 6292
chromatin 6.989E-6 4 77 3 6292
nuclear lumen 2.6539E-5 4 453 4 6292
nuclear chromosome part 1.0604E-4 4 190 3 6292
organelle lumen 1.2008E-4 4 660 4 6292
intracellular organelle lumen 1.2008E-4 4 660 4 6292
membrane-enclosed lumen 1.5203E-4 4 700 4 6292
nuclear chromosome 1.8288E-4 4 228 3 6292
chromosomal part 2.0528E-4 4 237 3 6292
chromosome 3.1631E-4 4 274 3 6292
nuclear part 9.4015E-4 4 1103 4 6292
protein complex 1.0617E-3 4 1137 4 6292
macromolecular complex 4.5471E-3 4 1635 4 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylation 2.8115E-7 4 27 3 6292
protein amino acid deacetylation 3.5113E-7 4 29 3 6292
covalent chromatin modification 1.0471E-5 4 88 3 6292
histone modification 1.0471E-5 4 88 3 6292
chromatin silencing at rDNA 4.6226E-5 4 18 2 6292
chromatin modification 7.3351E-5 4 168 3 6292
double-strand break repair via nonhomologous end joining 9.0505E-5 4 25 2 6292
chromatin organization 1.2926E-4 4 203 3 6292
chromatin silencing at silent mating-type cassette 1.5902E-4 4 33 2 6292
non-recombinational repair 1.6892E-4 4 34 2 6292
chromatin silencing at telomere 4.4515E-4 4 55 2 6292
double-strand break repair 4.7822E-4 4 57 2 6292
negative regulation of transcription from RNA polymerase II promoter 5.3002E-4 4 60 2 6292
post-translational protein modification 6.9425E-4 4 357 3 6292
positive regulation of transcription from RNA polymerase II promoter 1.0385E-3 4 84 2 6292
negative regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
gene silencing 1.4697E-3 4 100 2 6292
regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
chromatin silencing 1.4697E-3 4 100 2 6292
positive regulation of transcription, DNA-dependent 1.5586E-3 4 103 2 6292
positive regulation of RNA metabolic process 1.6812E-3 4 107 2 6292
positive regulation of transcription 1.8408E-3 4 112 2 6292
positive regulation of gene expression 1.8408E-3 4 112 2 6292
protein modification process 1.8668E-3 4 499 3 6292
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.0416E-3 4 118 2 6292
positive regulation of nitrogen compound metabolic process 2.0416E-3 4 118 2 6292
positive regulation of macromolecule biosynthetic process 2.0416E-3 4 118 2 6292
positive regulation of biosynthetic process 2.1458E-3 4 121 2 6292
positive regulation of cellular biosynthetic process 2.1458E-3 4 121 2 6292
positive regulation of macromolecule metabolic process 2.3251E-3 4 126 2 6292
positive regulation of metabolic process 2.436E-3 4 129 2 6292
positive regulation of cellular metabolic process 2.436E-3 4 129 2 6292
chromosome organization 2.5518E-3 4 555 3 6292
positive regulation of cellular process 2.7046E-3 4 136 2 6292
positive regulation of biological process 2.7441E-3 4 137 2 6292
macromolecule modification 2.7453E-3 4 569 3 6292
negative regulation of transcription, DNA-dependent 3.5916E-3 4 157 2 6292
negative regulation of RNA metabolic process 3.6369E-3 4 158 2 6292
negative regulation of transcription 3.9142E-3 4 164 2 6292
negative regulation of gene expression 3.9142E-3 4 164 2 6292
negative regulation of macromolecule biosynthetic process 4.4481E-3 4 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.7016E-3 4 180 2 6292
negative regulation of nitrogen compound metabolic process 4.7016E-3 4 180 2 6292
negative regulation of biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of cellular biosynthetic process 5.1748E-3 4 189 2 6292
DNA repair 5.3374E-3 4 192 2 6292
negative regulation of macromolecule metabolic process 5.3374E-3 4 192 2 6292
loss of chromatin silencing involved in replicative cell aging 5.7106E-3 4 9 1 6292
negative regulation of cellular metabolic process 6.3039E-3 4 209 2 6292
progressive alteration of chromatin involved in replicative cell aging 6.3436E-3 4 10 1 6292
loss of chromatin silencing 6.3436E-3 4 10 1 6292
negative regulation of metabolic process 6.3631E-3 4 210 2 6292
progressive alteration of chromatin involved in cell aging 6.9763E-3 4 11 1 6292
positive regulation of gene expression, epigenetic 6.9763E-3 4 11 1 6292
regulation of gene silencing 6.9763E-3 4 11 1 6292
negative regulation of gene silencing 6.9763E-3 4 11 1 6292
regulation of chromatin silencing 6.9763E-3 4 11 1 6292
negative regulation of chromatin silencing 6.9763E-3 4 11 1 6292
regulation of transcription from RNA polymerase II promoter 7.4744E-3 4 228 2 6292
response to DNA damage stimulus 7.9954E-3 4 236 2 6292
negative regulation of cellular process 8.9471E-3 4 250 2 6292
negative regulation of biological process 9.1576E-3 4 253 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription repressor activity 1.2704E-6 4 44 3 6292
transcription activator activity 3.4452E-6 4 61 3 6292
transcription regulator activity 8.286E-6 4 339 4 6292
transcription corepressor activity 3.6271E-5 4 16 2 6292
transcription coactivator activity 6.3408E-5 4 21 2 6292
histone deacetylase activity 1.4941E-4 4 32 2 6292
protein deacetylase activity 1.4941E-4 4 32 2 6292
deacetylase activity 1.7912E-4 4 35 2 6292
transcription cofactor activity 2.3456E-4 4 40 2 6292
transcription factor binding 2.7138E-4 4 43 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.3864E-4 4 48 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9.4222E-4 4 80 2 6292

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