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The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. The process by which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. Any epigenetic process that stops, prevents or reduces the rate of gene expression. Any epigenetic process that activates or increases the rate of gene expression. The removal of a methyl group from one or more nucleotides within an DNA molecule. Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes. The inactivation of gene expression by a posttranscriptional mechanism. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of gene expression, epigenetic
Acc: GO:0040029
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 770 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0040029 - regulation of gene expression, epigenetic (interactive image map)
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