YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any mating-type specific process that stops, prevents or reduces the rate of transcription. Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site. Any process that stops, prevents or reduces the DNA-dependent transcription of a specific gene or genes. Any process that stops, prevents or reduces the frequency, rate or extent of transcription during meiosis. Any cellular process that stops, prevents or reduces the frequency, rate or extent of transcription. Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter. Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription. The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Any process that decreases the rate, frequency or extent of transcription termination. Transcription termination is the process by which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process involving carbon catabolites that stops, prevents or reduces the rate of transcription. Carbon catabolite repression is a mechanism of genetic regulation in bacteria in which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. The cellular synthesis of RNA on a template of DNA. The cellular synthesis of either RNA on a template of DNA or DNA on a template of RNA. Any process involving nitrogen catabolites that stops, prevents or reduces the rate of transcription. Any cellular process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any process involving pheromones that stops, prevents or reduces the rate of transcription. Any process that stops, prevents or reduces the frequency, rate or extent of transcription during mitosis. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter. The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a transcription factor. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription. Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transcription, DNA-dependent
Acc: GO:0045892
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
Synonyms:
  • negative regulation of cellular transcription, DNA-dependent
  • downregulation of transcription, DNA-dependent
  • inhibition of transcription, DNA-dependent
  • down regulation of transcription, DNA-dependent
  • down-regulation of transcription, DNA-dependent
Proteins in PDR annotated with:
   This term: 247 [Search]
   Term or descendants: 1345 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045892 - negative regulation of transcription, DNA-dependent (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle