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The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. Any epigenetic process that activates or increases the rate of gene expression. The process leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. Any process that affects the rate, extent or location of chromatin silencing. Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that activates or increases the frequency, rate or extent of cellular DNA-dependent transcription. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: loss of chromatin silencing
Acc: GO:0006345
Aspect: Biological Process
Desc: The process leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006345 - loss of chromatin silencing (interactive image map)
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