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Protein Overview: RSE1

General Information:
Name(s) found: RSE1 / YML049C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1361 amino acids

    Gene Ontology:
    Cellular Component: U2 snRNP [IDALink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    Biological Process: spliceosome assembly [IDALink to PubMed article]
    nuclear mRNA splicing, via spliceosome [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: U2 snRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGGGKMAVV SLSPHTAKMR KLFGQASTTM AYDGLKREAE RRTRSDHNIT MVAKDDELYL  60
   61 YHLTLKKQTN FVHSCIGHFV DLEAGSKREQ SQLCVATETH LELYDTADGE LKLIAKFQNL 120
  121 FATITSMKSL DLPHSGSRAK ASNWPTFLAL TSDSGNLSIV QIIMHAGALR LKTLVNQPLT 180
  181 RTTLRRVSPI SYMEIDPNGR CIILSSVEQN KLCFLVDYAQ KLRISSPLEI IRPHMVTLDM 240
  241 AVVDVNFNNP CFVTLEIDNA ATQLSVHLIF YVLELGLNHI VKKADYLVNP SANFVLSLPD 300
  301 LSRYNITTSL SDNNYDADYD TLFNPFVVIG FENHILVKDM NGFFSLKVEI PKRSITNSRH 360
  361 KNVTIISGIV QKLKNDFFVL LQSNHGDLFK LTVSPDTNDR NRPLVQLSYF DTIQNSHQLH 420
  421 IFKNGYLFAL SEMNNNFLFQ FEKLGVEKND FSNVLTSKDP NKSLVFEPSI KLQNLSILSQ 480
  481 QLNLNPSIKS QIVSDSPLSI ATKHFTNNKI ITLTNAVNYS NLISTSLPPN ATKLWLIPDP 540
  541 ATTGDNNTLL FITFPKKTMI LQIDNESMEE LTPDEATRSA FKLSQDTTIH TCLMGSHSII 600
  601 QVCTAELRHI VPTGKSRYSN KLTWVPPAGI RIVCATSSKT QLIISLSNYE LVYFKIDVSS 660
  661 DSLIELTTHP ELDTMPSKVA IVQDTQHADL LAIADNEGMI KIMSLKDQKE DFLTVISLQL 720
  721 VSEKISDMIM VRDSSIGQLN LHVGLENGVY MKFHIGDVDG SFTDIKRRFL GLKPVSLSYL 780
  781 REISVSLNNE EEEEEEEDDD DEKEEEEINS SGAKWMSCVV CHSSSTWVSY TWKNVWTIRQ 840
  841 LKDQNMLSCS KFVNADVAIN GVCSISSSGR LNIGRVSNFP TLDNWFHVHE SSVNKQENGG 900
  901 GDESNEEEED EMEEEMEMLQ ISTFRPRTIL SFPNNPKSIL FIDNHSGKKQ CRISLQIDGE 960
  961 CLKFGSSDHL YKILDDIDCV SAAIIDFTRQ ADHLIICAGD KRLLTYKILV NKDKLSFDIE1020
 1021 LLHQTEIISP IHAMLKFKNF LLTAMGSTIV LYGLGKKQLL RRSVTQTPVS ITKIVSMHQW1080
 1081 NYERLAVGDI HESVTLFIWD PAGNVFIPYV DDSVKRHVTV LKFLDEATVI GADRYGNAWT1140
 1141 LRSPPECEKI MSNHDPSELS NGAIKYPLDV ITLQQKLPNT YDCKFKFQLL NHFFVNDIIT1200
 1201 DFHILDSLSN SDRPGCIYMG LQGTVGCFIP LLSKGNVFMM GNIENIMAEA DDTFYLDYES1260
 1261 RKKNNNMRKE DDEEESGSVV LQGRHGIEDE IICEGSCSIL GRDHQEYRSY YAPVRKVIDG1320
 1321 DLCENFLRLS LNEQEFLAKN LKSVQVEDII QTINEVRTNY M

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BRR1 BRR2 BUD31 CDC40 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DIB1 ECM2 HSH155 HSH49 LEA1 LUC7 MSL1 NAM8 PRP11 PRP19 PRP21 PRP3 PRP31 PRP39 PRP4 PRP40 PRP42 PRP43 PRP45 PRP46 PRP6 PRP8 PRP9 RSE1 SMB1 SMD1 SMD2 SMD3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP382 STO1 SYF1 TIF4631
    View Details Krogan NJ, et al. (2006) BUD13 BUD31 CUS1 CWC21 HSH155 HSH49 LEA1 LOT6 PRP11 PRP21 PRP45 PRP9 RSE1
    View Details Gavin AC, et al. (2006) CUS1 HSH155 HSH49 LEA1 MSL1 PRP11 PRP21 PRP9 RSE1
    View Details Gavin AC, et al. (2002) AAR2 AIR2 BRR1 BUD31 BUR2 CBC2 CDC33 CDC40 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DHH1 DIB1 ECM2 GCN2 HRT1 HSH155 HSH49 HTA1 IMG1 ISY1 KAP95 LEA1 LIN1 LSM1 LSM2 LSM4 LSM5 LSM6 LSM7 LUC7 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS5 MSH4 MSL1 MUD1 NAB3 NAB6 NAM8 NPL3 NRD1 NUP60 PAT1 PRP11 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP45 PRP46 PRP6 PRP8 PRP9 RSE1 RVB2 SCP160 SEN1 SGV1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SRB2 SRO9 SRP1 STO1 SYF1 THO2 TIF4631 TIF4632 TOS4 UTP21 YEF3 YML6 YRA2
    View Details Ho Y, et al. (2002) CHD1 CPR1 GLC7 HSH49 HXT6 KOG1 MLC2 NET1 NOP6 NSR1 PMA1 PMA2 PPZ2 REG1 RSE1 RVB1 SDS22 SNF4 YGR130C
    View Details Qiu et al. (2008) AAR2 BRR1 BRR2 CBC2 CDC40 CEF1 CLF1 CUS1 CUS2 CWC15 CWC2 CWC22 CWC23 DIB1 HSH155 HSH49 IST3 ISY1 LEA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 LSM8 LUC7 MAK5 MSL1 MSL5 MUD1 MUD2 NAM8 NTC20 PRP11 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP5 PRP6 PRP8 PRP9 RDS3 RSE1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP2 SPP381 SPP382 STO1 SUB2 SYF1 SYF2 YHC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CWC2 No Comments Hazbun TR, et al. (2003)
    View Run PAN1 No Comments Toshima J, et al (2006)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RSE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..858] MSA 3.030902 View MSA. No confident structure predictions are available.
    2 View Details [859..932] deduced N/A No confident structure predictions are available.
    3 View Details [933..1361] Pfam 119.113509 CPSF A subunit region No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle