YRC Public Data Repository - Protein Structure Prediction

Protein:	RSE1
Organism:	Saccharomyces cerevisiae
Length:	1361 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSE1.

Description	E-value	Query Range	Subject Range
tr\|G3HAF4\|G3HAF4... - Splicing factor 3B subunit 3 OS=Cricetulus griseus GN=I79_007403 PE=4 SV=1 tr\|E9PT66\|E9PT66_RAT - Protein Sf3b3 OS=Rattus norvegicus GN=Sf3b3 PE=4 SV=2 SF3B3_MOUSE - Splicing factor 3B subunit 3 OS=Mus musculus GN=Sf3b3 PE=1 SV=1	0.0	[58..1360]	[1..1215]
gi\|18410226, gi\|... - gi\|7019655\|emb\|CAB75756.1\| spliceosomal-like protein [Arabidopsis thaliana], gi\|7019653\|emb\|CAB75754...	0.0	[58..1357]	[1..1210]
RSE1_YEAST - Pre-mRNA-splicing factor RSE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RSE1 PE=1 ... RSE1 - Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; i... gi\|190408196 - gi\|190408196\|gb\|EDV11461.1\| pre-mRNA splicing factor RSE1 [Saccharomyces cerevisiae RM11-1a]	0.0	[1..1361]	[1..1361]
SF3B3 - splicing factor 3b, subunit 3, 130kDa	0.0	[58..1360]	[1..1215]
tag-203 - status:Partially_confirmed UniProt:O44985 protein_id:AAB97566.1	0.0	[58..1360]	[1..1218]
RSE1_SCHPO - Pre-mRNA-splicing factor prp12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=prp12 PE=1 ... prp12 - U2 snRNP-associated protein Sap130	0.0	[57..1359]	[6..1204]
DDB1_CHLAE - DNA damage-binding protein 1 OS=Chlorocebus aethiops GN=DDB1 PE=1 SV=1	0.0	[59..1356]	[3..1136]

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Predicted Domain #1

Region A:
Residues: [1-858]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGGGKMAVV SLSPHTAKMR KLFGQASTTM AYDGLKREAE RRTRSDHNIT MVAKDDELYL  60
   61 YHLTLKKQTN FVHSCIGHFV DLEAGSKREQ SQLCVATETH LELYDTADGE LKLIAKFQNL 120
  121 FATITSMKSL DLPHSGSRAK ASNWPTFLAL TSDSGNLSIV QIIMHAGALR LKTLVNQPLT 180
  181 RTTLRRVSPI SYMEIDPNGR CIILSSVEQN KLCFLVDYAQ KLRISSPLEI IRPHMVTLDM 240
  241 AVVDVNFNNP CFVTLEIDNA ATQLSVHLIF YVLELGLNHI VKKADYLVNP SANFVLSLPD 300
  301 LSRYNITTSL SDNNYDADYD TLFNPFVVIG FENHILVKDM NGFFSLKVEI PKRSITNSRH 360
  361 KNVTIISGIV QKLKNDFFVL LQSNHGDLFK LTVSPDTNDR NRPLVQLSYF DTIQNSHQLH 420
  421 IFKNGYLFAL SEMNNNFLFQ FEKLGVEKND FSNVLTSKDP NKSLVFEPSI KLQNLSILSQ 480
  481 QLNLNPSIKS QIVSDSPLSI ATKHFTNNKI ITLTNAVNYS NLISTSLPPN ATKLWLIPDP 540
  541 ATTGDNNTLL FITFPKKTMI LQIDNESMEE LTPDEATRSA FKLSQDTTIH TCLMGSHSII 600
  601 QVCTAELRHI VPTGKSRYSN KLTWVPPAGI RIVCATSSKT QLIISLSNYE LVYFKIDVSS 660
  661 DSLIELTTHP ELDTMPSKVA IVQDTQHADL LAIADNEGMI KIMSLKDQKE DFLTVISLQL 720
  721 VSEKISDMIM VRDSSIGQLN LHVGLENGVY MKFHIGDVDG SFTDIKRRFL GLKPVSLSYL 780
  781 REISVSLNNE EEEEEEEDDD DEKEEEEINS SGAKWMSCVV CHSSSTWVSY TWKNVWTIRQ 840
  841 LKDQNMLSCS KFVNADVA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [859-932]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INGVCSISSS GRLNIGRVSN FPTLDNWFHV HESSVNKQEN GGGDESNEEE EDEMEEEMEM  60
   61 LQISTFRPRT ILSF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [933-1361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNNPKSILFI DNHSGKKQCR ISLQIDGECL KFGSSDHLYK ILDDIDCVSA AIIDFTRQAD  60
   61 HLIICAGDKR LLTYKILVNK DKLSFDIELL HQTEIISPIH AMLKFKNFLL TAMGSTIVLY 120
  121 GLGKKQLLRR SVTQTPVSIT KIVSMHQWNY ERLAVGDIHE SVTLFIWDPA GNVFIPYVDD 180
  181 SVKRHVTVLK FLDEATVIGA DRYGNAWTLR SPPECEKIMS NHDPSELSNG AIKYPLDVIT 240
  241 LQQKLPNTYD CKFKFQLLNH FFVNDIITDF HILDSLSNSD RPGCIYMGLQ GTVGCFIPLL 300
  301 SKGNVFMMGN IENIMAEADD TFYLDYESRK KNNNMRKEDD EEESGSVVLQ GRHGIEDEII 360
  361 CEGSCSILGR DHQEYRSYYA PVRKVIDGDL CENFLRLSLN EQEFLAKNLK SVQVEDIIQT 420
  421 INEVRTNYM

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	119.113509
Match:	PF03178
Description:	CPSF A subunit region

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits