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Protein Overview: TAF3

General Information:
Name(s) found: TAF3 / YPL011C [SGD]
Description(s) found:
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  • gi|965082|gb|AAB68094.1| Lpa6p [NCBI NR]
  • gi|683779|emb|CAA88375.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6325246|ref|NP_015314.1| TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation; Taf3p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|42559734|sp|Q12297.1|TAF3_YEAST RecName: Full=Transcription initiation factor TFIID subunit 3; AltName: Full=TBP-associated factor 3; AltName: Full=TBP-associated factor 47 kDa; AltName: Full=TAFII-47; Short=TAFII47 [NCBI NR]
  • gi|1314065|emb|CAA95030.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S52520 hypothetical protein YPL011c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Transcription initiation factor TFIID subunit 3 OS=Saccharomyces cerevisiae GN=TAF3 PE=1 SV=1 [Swiss-Prot]
  • TAF3 Component of the TBP-associated protein complex [mips]
  • TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation [SGD]
  • >Q12297 (Q12297) Hypothetical protein YPL011C [4932.FASTACCERV.txt]
  • Chr XVI from 534698-533637, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XVI from 533637-534698, reverse complement [yeastorf3.fasta]
  • TAF47, Chr XVI from 533637-534698, reverse complement [yeast_orfs2]
  • TAF3 SGDID:S0005932, Chr XVI from 534698-533637, reverse complement, Verified ORF [yeastflysequest.fasta]
  • TAF3 SGDID:S0005932, Chr XVI from 534700-533639, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation [Saccharomyces cerevisiae]gi|683779|emb|CAA88375.1| unknown [Saccharomyces cerevisiae]gi|1314065|emb|CAA95030.1| unknown [Saccharomyces cerevisiae]gi|42 [nrdb_11152004_Chlamydomonas]
  • (Q12297) Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (TBP-associated factor 47 kDa) (TAFII-47) (TAFII47) [cerv4932.FASTAC]
  • TAF3 SGDID:S000005932, Chr XVI from 534700-533639, reverse complement, Verified ORF, "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (TBP-associated factor 47 kDa) (TAFII-47) (TAFII47) [nr-271106-contam.fasta]
  • TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation; Taf3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Lpa6p [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Transcription initiation factor TFIID subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAF3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • TAF3 SGDID:S000005932, Chr XVI from 534703-533642, Genome Release 64-1-1, reverse complement, Verified ORF, "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" [yeast-030211-contam.fasta]
  • TAF3 SGDID:S000005932, Chr XVI from 534703-533642, Genome Release 64-2-1, reverse complement, Verified ORF, "TFIID subunit (47 kDa); involved in promoter binding and RNA polymerase II transcription initiation" [20141208_orf_trans.fasta]
  • YPL011C SGDID:S000005932, Chr XVI from 534703-533642, Genome Release 64-1-1, reverse complement, Verified ORF, "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: regulation of transcription involved in G1 phase of mitotic cell cycle [IPILink to PubMed articleLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTNNDFYFA LLRISILQLL KAQGFDRARP SLVDVMTDLY AKFLSLLASE VSSIAQARCD  60
   61 QDDTIALQDI TLALENLGIV KPTNVLDVYD ENSELSSSRG MEKFKDWCIY STQLTDARIT 120
  121 ALPTVELLQS EEKESDPLSA IPDYLNQLLQ NKGAKQKLET KNRKTELIED LINNNGLDDW 180
  181 IKLVIARQRI NMIERASKKE SQNVPALPHI AGYKSSILSR HHHTTITNED RMPSAMTPRD 240
  241 EDALTEIQEN PFVTSKLPIM RKENRLENIT LSFEDEELES LGEVEGPNQK SQENNNEESF 300
  301 KENNKSLTES PHGDDRDISM FQFDSNVDTK WAEQEDMDST FQRRTSLDYG GYF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ADA2 HFI1 NGG1 SGF73 SPT15 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9
    View Details (MIPS) Mewes HW, et al. (2004) TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9
    View Details Krogan NJ, et al. (2006) ADA2 AHC1 AHC2 FMP40 GCN5 HFI1 MSS4 NGG1 PDR15 RAD59 REV3 SGF11 SGF29 SGF73 SNL1 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8 YMR007W
    View Details Gavin AC, et al. (2006) SPT15 TAF1 TAF11 TAF12 TAF3 TAF4 TAF5 TAF9
    View Details Gavin AC, et al. (2002) ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 HFI1 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 MYO4 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 UBP8 VAS1 VPS1
    View Details Qiu et al. (2008) ADA2 GAL11 GCN5 HFI1 MED2 MED6 NGG1 NUT1 RGR1 SGF29 SGF73 SIN4 SPT15 SPT20 SPT3 SPT7 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF8 TAF9 TFB5 TRA1 UBP8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen INP52 TAF3 1 Unpublished Fields Lab Data
    View Screen NAF1 TAF3 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TAF3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] MSA 2.003972 View MSA. No confident structure predictions are available.
    2 View Details [153..353] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.88482968293417 bayes_pls_golite062009
  • DNA binding
    		•  4.24660531286828 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.14026521609645 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  3.94678088447927 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  3.94678088447927 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.91807454227165 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  3.78067108255869 bayes_pls_golite062009
  • binding
    		•  3.14832737946099 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.02428691626433 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  2.46003121267868 bayes_pls_golite062009
  • transcription factor activity
    		•  2.39322722597434 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  2.22658570487778 bayes_pls_golite062009
  • acetyltransferase activity
    		•  1.87240886310988 bayes_pls_golite062009
  • transcription activator activity
    		•  1.12739348005764 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03060091158028 bayes_pls_golite062009
  • protein binding
    		•  1.01897642648285 bayes_pls_golite062009
  • transcription factor binding
    		•  1.01773884290535 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.976797801726735 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.840442755533537 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.621482805601238 bayes_pls_golite062009
  • histone binding
    		•  0.184823910505751 bayes_pls_golite062009
  • acyltransferase activity
    		•  0.133449022804582 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  0.131532799941764 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0919482386963733 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0585868733603467 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle