Protein Overview: RPB10

General Information:
Name(s) found:	RPB10 / YOR210W [SGD]
Description(s) found: Found 114 descriptions. SHOW ALL	RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III [SGD]
Organism:	Saccharomyces cerevisiae
Length:	70 amino acids
Gene Ontology:
Cellular Component:	DNA-directed RNA polymerase I complex [TAS] DNA-directed RNA polymerase III complex [TAS] DNA-directed RNA polymerase II, core complex [TAS]
Biological Process:	transcription from RNA polymerase III promoter [TAS] transcription from RNA polymerase I promoter [TAS] transcription from RNA polymerase II promoter [TAS]
Molecular Function:	DNA-directed RNA polymerase activity [TAS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MIVPVRCFSC GKVVGDKWES YLNLLQEDEL DEGTALSRLG LKRYCCRRMI LTHVDLIEKF 60 61 LRYNPLEKRD

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		DST1 IWR1 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC17 RPC19 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31 SPT4 SPT5 TFG1 TFG2
View Details	(MIPS) Mewes HW, et al. (2004)		CDC73 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC19 RPC25 RPC31 RPC34 RPC40 RPC82 RPO21 RPO26 RPO31
View Details	Krogan NJ, et al. (2006)		ALG3 BUD27 CBF2 DST1 ESS1 IWR1 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPO21 RPO26 SPT4 TAF14 TFG1 TFG2 YBL059W YBR259W YPL225W
View Details	Gavin AC, et al. (2002)		AMS1 ASC1 CDC14 DHH1 FBA1 MAF1 RET1 RPA12 RPA135 RPA190 RPA43 RPA49 RPB10 RPB5 RPB8 RPC11 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO26 RPO31 RSC8 SRO7
View Details	Ho Y, et al. (2002)		ALA1 AXL1 DBF20 EGD2 GPH1 IDH2 MOB1 RPB10
View Details	Qiu et al. (2008)		CDC73 RET1 RPA12 RPA135 RPA14 RPA190 RPA34 RPA43 RPA49 RPB10 RPB11 RPB2 RPB3 RPB4 RPB5 RPB7 RPB8 RPB9 RPC10 RPC17 RPC19 RPC25 RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO21 RPO26 RPO31 TFG1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#08 Alpha Factor Prep4-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PRP42	RPB10	1	Unpublished Fields Lab Data
View Screen	SAM35	RPB10	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	RPB10	Huh WK, et al. (2003)
View Data	RPB10 and NOP56	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..70]	PSI-BLAST	350.165202	RNA polymerase subunit RPB10

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
DNA-directed RNA polymerase activity	8.75117285798821	bayes_pls_golite062009
RNA polymerase activity	8.75117285798821	bayes_pls_golite062009
nucleotidyltransferase activity	6.19778374025439	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	4.14604589390528	bayes_pls_golite062009
transferase activity	3.67290653698956	bayes_pls_golite062009
binding	1.92719310476535	bayes_pls_golite062009
catalytic activity	0.740488970089403	bayes_pls_golite062009
protein binding	0.445041376423941	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle