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Protein Overview: SAM35

General Information:
Name(s) found: SAM35 / YHR083W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 329 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    extrinsic to membrane [IDALink to PubMed article]
    mitochondrial sorting and assembly machinery complex [IDALink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    Biological Process: protein import into mitochondrial outer membrane [ICLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSSFSVPMP VKRIFDTFPL QTYAAQTDKD EAVALEIQRR SYTFTERGGG SSELTVEGTY  60
   61 KLGVYNVFLE ANTGAALATD PWCLFVQLAL CQKNGLVLPT HSQEQTPSHT CNHEMLVLSR 120
  121 LSNPDEALPI LVEGYKKRII RSTVAISEIM RSRILDDAEQ LMYYTLLDTV LYDCWITQII 180
  181 FCASDAQFME LYSCQKLSGS IVTPLDVENS LLQKLSAKSL KISLTKRNKF QFRHREIVKS 240
  241 MQGVYHNHHN SVNQEQVLNV LFENSKQVLL GLKDMLKSDG QPTYLHLKIA SYILCITNVK 300
  301 EPIKLKTFVE NECKELVQFA QDTLKNFVQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) SAM35 SAM37 SAM50

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SAM35 YNL092W 2 Uetz P, et al. (2000)
    View Screen SAM35 SNF11 2 Unpublished Fields Lab Data
    View Screen SAM35 BCY1 2 Unpublished Fields Lab Data
    View Screen SAM35 APL2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SAM35 and TRX3 Hazbun TR, et al. (2003)
    View Data SAM35 and SPC42 Hazbun TR, et al. (2003)
    View Data SAM35 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] deduced N/A No confident structure predictions are available.
    2 View Details [112..329] MSA 1.002892 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle