Protein Overview: SAM37

General Information:
Name(s) found:	SAM37 / YMR060C [SGD]
Description(s) found: Found 29 descriptions. SHOW ALL	Component of the Sorting and Assembly Machinery (SAM or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; contributes to SAM complex stability [SGD]
Organism:	Saccharomyces cerevisiae
Length:	327 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial outer membrane [IDA] mitochondrial sorting and assembly machinery complex [IDA]
Biological Process:	outer mitochondrial membrane organization [IDA][IMP]
Molecular Function:	protein binding [IMP][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKGSVHLWG KDGKASLISV DSIALVWFIK LCTSEEAKSM VAGLQIVFSN NTDLSSDGKL  60
   61 PVLILDNGTK VSGYVNIVQF LHKNICTSKY EKGTDYEEDL AIVRKKDRLL EYSLLNYVDV 120
  121 EISRLTDYQL FLNTKNYNEY TKKLFSKLLY FPMWYNTPLQ LRSQARENCE EIIGSLTLED 180
  181 DEEFVESKAM ESASQLAQSK TFKIAHKNKI KGKQELQQVK YNLQFDNRLQ SCVSNWLAAR 240
  241 KKLDDSVILS SDLLFLANLY VQLGLPDGNR IRSKLEQTFG SELLNSMSNK IDDFVHRPSN 300
  301 NLEQRDPQFR EQGNVVMSLY NLACKYI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		SAM37 TOM20 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOM71
View Details	Qiu et al. (2008)		MDM10 SAM35 SAM37 SAM50 TOM7 TOM70

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	SAM37	Huh WK, et al. (2003)

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
transporter activity	1.28554239680317	bayes_pls_golite062009
transmembrane transporter activity	1.08450741397919	bayes_pls_golite062009
substrate-specific transporter activity	0.863830764503551	bayes_pls_golite062009
binding	0.755744666560865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.650692022443636	bayes_pls_golite062009
catalytic activity	0.646676412582618	bayes_pls_golite062009
nucleic acid binding	0.477374722943518	bayes_pls_golite062009
ion transmembrane transporter activity	0.416095918947547	bayes_pls_golite062009
protein binding	0.376412693567268	bayes_pls_golite062009
transcription regulator activity	0.374519363311304	bayes_pls_golite062009
DNA binding	0.187513855814277	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..327]	deduced	N/A	No confident structure predictions are available.

Protein Overview: SAM37

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: