Protein Overview: TAF13

General Information:
Name(s) found:	TAF13 / YML098W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6323540\|ref\|NP_013611.1\| TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors; Taf13p [Saccharomyces cerevisiae] [NCBI NR] gi\|575704\|emb\|CAA86639.1\| FUN81 [Saccharomyces cerevisiae] [NCBI NR] gi\|45269417\|gb\|AAS56089.1\| YML098W [Saccharomyces cerevisiae] [NCBI NR] gi\|1346053\|sp\|P11747.2\|TAF13_YEAST RecName: Full=Transcription initiation factor TFIID subunit 13; AltName: Full=TBP-associated factor 13; AltName: Full=TBP-associated factor 19 kDa; AltName: Full=TAFII-19; Short=TAFII19; AltName: Full=Function unknown 81 [NCBI NR] pir\|\|S49628 FUN81 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] (P11747) Transcription initiation factor TFIID subunit 13 (TBP-associated factor 13) (TBP-associated factor 19 kDa) (TAFII-19) (TAFII19) (Function unknown 81 protein) [Swiss-Prot] Transcription initiation factor TFIID subunit 13 OS=Saccharomyces cerevisiae GN=TAF13 PE=1 SV=2 [Swiss-Prot] TAF13 TFIID subunit (TBP-associated factor), 19 kD [mips] TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors [SGD] TAF19, Chr XIII from 77267-77770 [yeast_orfs2] Chr XIII from 77267-77770 [yeastorf3.fasta] (P11747) Transcription initiation factor TFIID 19 kDa subunit (TAFII-19) (TAFII19) [4932.FASTACCERV.txt] TAF13 SGDID:S0004564, Chr XIII from 77267-77770, Verified ORF [yeastflysequest.fasta] TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors [Saccharomyces cerevisiae]gi\|575704\|emb\|CAA86639.1\| FUN81 [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] TAF13 SGDID:S000004564, Chr XIII from 77267-77770, Verified ORF, "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Transcription initiation factor TFIID subunit 13 (TBP-associated factor 13) (TBP-associated factor 19 kDa) (TAFII-19) (TAFII19) (Function unknown 81 protein) [nr-271106-contam.fasta] YML098W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] FUN81 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors; Taf13p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Transcription initiation factor TFIID subunit 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAF13 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TAF13 SGDID:S000004564, Chr XIII from 77267-77770, Genome Release 64-1-1, Verified ORF, "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" [yeast-030211-contam.fasta] TAF13 SGDID:S000004564, Chr XIII from 77267-77770, Genome Release 64-2-1, Verified ORF, "TFIID subunit (19 kDa); involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" [20141208_orf_trans.fasta] TR6504\|c0_g1_i1\|g.4596 ORF TR6504\|c0_g1_i1\|g.4596 TR6504\|c0_g1_i1\|m.4596 type:complete len:168 (+) TR6504\|c0_g1_i1:93-596(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR1909\|c0_g1_i1\|g.1323 ORF TR1909\|c0_g1_i1\|g.1323 TR1909\|c0_g1_i1\|m.1323 type:complete len:168 (+) TR1909\|c0_g1_i1:31-534(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YML098W SGDID:S000004564, Chr XIII from 77267-77770, Genome Release 64-1-1, Verified ORF, "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_4507\|g.3146 ORF asmbl_4507\|g.3146 asmbl_4507\|m.3146 type:complete len:168 (+) asmbl_4507:93-596(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_4510\|g.2770 ORF ID=asmbl_4510\|g.2770 ID=asmbl_4510\|m.2770 type:complete len:168 (+) ID=asmbl_4510:21-524(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_4513\|g.2717 ORF ID=asmbl_4513\|g.2717 ID=asmbl_4513\|m.2717 type:complete len:168 (+) ID=asmbl_4513:93-596(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	167 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] transcription factor TFIID complex [IDA][TAS]
Biological Process:	regulation of transcription involved in G1 phase of mitotic cell cycle [IPI ] transcription initiation from RNA polymerase II promoter [TAS ]
Molecular Function:	general RNA polymerase II transcription factor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKLKKTNL FNKDVSSLLY AYGDVPQPLQ ATVQCLDELV SGYLVDVCTN AFHTAQNSQR  60
   61 NKLRLEDFKF ALRKDPIKLG RAEELIATNK LITEAKKQFN ETDNQNSLKR YREEDEEGDE 120
  121 MEEDEDEQQV TDDDEEAAGR NSAKQSTDSK ATKIRKQGPK NLKKTKK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF9
View Details	Krogan NJ, et al. (2006)		ADA2 AHC1 AHC2 FMP40 GCN5 HFI1 MSS4 NGG1 PDR15 RAD59 REV3 SGF11 SGF29 SGF73 SNL1 SPT20 SPT3 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF3 TAF4 TAF5 TAF6 TAF7 TAF9 UBP8 YMR007W
View Details	Gavin AC, et al. (2002)		ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 VAS1 VPS1
View Details	Qiu et al. (2008)		GCN5 HFI1 ROX3 SGF29 SGF73 SPT15 SPT20 SPT3 SPT7 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF5 TAF6 TAF7 TAF8 TAF9 TFB5 TRA1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BEM1	TAF13	1	Unpublished Fields Lab Data
View Screen	AIM13	TAF13	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	TAF13	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..54]	PSI-BLAST	14.0	TAF(II)18
2	View Details	[55..167]	Pfam	5.958607	Transcription initiation factor IID, 18kD subunit No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	8.88482968293417	bayes_pls_golite062009
DNA binding	4.24660531286828	bayes_pls_golite062009
nucleic acid binding	4.14026521609645	bayes_pls_golite062009
transcription regulator activity	3.91807454227165	bayes_pls_golite062009
transcription initiation factor activity	3.78067108255869	bayes_pls_golite062009
binding	3.14832737946099	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.02428691626433	bayes_pls_golite062009
transcription factor activity	2.39322722597434	bayes_pls_golite062009
transcription activator activity	1.12739348005764	bayes_pls_golite062009
nucleotidyltransferase activity	1.03060091158028	bayes_pls_golite062009
protein binding	1.01897642648285	bayes_pls_golite062009
transcription factor binding	1.01773884290535	bayes_pls_golite062009
transcription coactivator activity	0.976797801726735	bayes_pls_golite062009
transcription cofactor activity	0.840442755533537	bayes_pls_golite062009
transcription repressor activity	0.621482805601238	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0919482386963733	bayes_pls_golite062009
sequence-specific DNA binding	0.0585868733603467	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.88

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2