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Protein Overview: YFR006W

General Information:
Name(s) found: YFR006W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: X-Pro aminopeptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCLEPISLVV FGSLVFFFGL VKYFKRGERQ RTRGILQPEY KDKYYYSKEK GEEMGEVANV  60
   61 NEIPVKIRNH KYPAKEHNLR VKDLLLNRNP KLSKISTAFF IAGEELEGNK YCDTNKDFRQ 120
  121 NRYFYHLSGV DIPASAILFN CSTDKLTLFL PNIDEEDVIW SGMPLSLDEA MRVFDIDEAL 180
  181 YISDLGKKFK ELQDFAIFTT DLDNVHDENI ARSLIPSDPN FFYAMDETRA IKDWYEIESI 240
  241 RKACQISDKS HLAVMSALPI ELNELQIQAE FEYHATRQGG RSLGYDPICC SGPACGTLHY 300
  301 VKNSEDIKGK HSILIDAGAE WRQYTSDITR CFPTSGKFTA EHREVYETVL DMQNQAMERI 360
  361 KPGAKWDDLH ALTHKVLIKH FLSMGIFKKE FSEDEIFKRR ASCAFYPHGL GHMLGLDVHD 420
  421 VGGNPNYDDP DPMFRYLRIR RPLKENMVIT NEPGCYFNQF LIKEFLEKHP ERLEVVDMSV 480
  481 LKRYMYVGGV RIEDDILVTK DGYENLTGIT SDPDEIEKIV QKGLKKPRSG FHVIV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) MAC1 YFR006W
    View Details Gavin AC, et al. (2006) ECM5 PSD2 PSH1 YFR006W
    View Details Gavin AC, et al. (2002) BDF2 CDC55 CKB1 DYN1 ECM5 GLY1 HAT1 HAT2 HHF1, HHF2 HIF1 HSM3 ICL1 IML1 KAP123 KRE33 LIP2 MAC1 MDN1 MIS1 MSB1 NIP1 NMD5 PFK1 PRO1 PRT1 PSD2 PSE1 PSH1 RPA135 RPC40 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPT2 RPT3 RPT5 RPT6 RSC3 SAM1 TEL1 TSC11 USO1 UTP20 VTH2 YFR006W YPR077C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CAB5 No Comments Hazbun TR, et al. (2003)
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YFR006W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..227] PSI-BLAST 508.9691 Aminopeptidase P; Aminopeptidase P, C-terminal domain
    2 View Details [228..535] PSI-BLAST 508.9691 Aminopeptidase P; Aminopeptidase P, C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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