YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Gavin A.C. et al. (2002) Abstract Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 2002 Jan 10;415(6868):141-7.
Notes:	From the published set of protein complexes.
Complex Size:	23 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
CLU1	cytoplasm eukaryotic translation initiation factor 3 complex	translational initiation mitochondrion organization	molecular_function
CRN1	actin cortical patch	actin filament organization microtubule-based process	actin filament binding protein binding, bridging microtubule binding
ECM29	nucleus cytoplasm proteasome complex	protein catabolic process	protein binding
KAP123	nucleus cytoplasm nuclear pore	protein import into nucleus	protein transmembrane transporter activity
MEC1	nucleus mitochondrion	DNA damage checkpoint DNA replication checkpoint reciprocal meiotic recombination DNA recombination telomere maintenance telomere maintenance via recombination nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	protein kinase activity
MIP6	nuclear pore	mRNA export from nucleus	RNA binding
MIS1	mitochondrion	ribosome biogenesis folic acid biosynthetic process anaerobic purine catabolic process nucleobase, nucleoside, nucleotide and nucleic acid metabolic process acetate biosynthetic process from carbon monoxide	formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity
MRPL23	mitochondrion mitochondrial large ribosomal subunit	ribosomal large subunit assembly translation	structural constituent of ribosome
NAB3	nucleus	termination of RNA polymerase II transcription, poly(A)-independent regulation of transcription from RNA polymerase II promoter	poly(A) RNA binding
NAB6	cytoplasm	RNA metabolic process	molecular_function
NRD1	nuclear exosome (RNase complex) nucleus	termination of RNA polymerase II transcription, poly(A)-independent	RNA binding
ROM2	cellular bud tip	small GTPase mediated signal transduction cellular cell wall organization actin filament organization endocytosis budding cell bud growth response to stress	Rho guanyl-nucleotide exchange factor activity signal transducer activity
RPA135	DNA-directed RNA polymerase I complex	transcription from RNA polymerase I promoter ribosome biogenesis	DNA-directed RNA polymerase activity
SEN54	nuclear inner membrane mitochondrion tRNA-intron endonuclease complex mitochondrial outer membrane	tRNA splicing, via endonucleolytic cleavage and ligation	tRNA-intron endonuclease activity
SUI3	multi-eIF complex ribosome eukaryotic translation initiation factor 2 complex	translational initiation	translation initiation factor activity
SUP35	cytosol translation release factor complex	translational termination nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	translation release factor activity
SUP45	cytosol translation release factor complex	translational termination cytokinesis	translation release factor activity, codon specific
TAO3	incipient cellular bud site cellular bud mitochondrion mating projection tip	cell morphogenesis during vegetative growth cell morphogenesis cell budding	molecular_function
USO1	soluble fraction	ER to Golgi vesicle-mediated transport protein complex assembly	molecular_function
UTP20	cytoplasm nuclear outer membrane nucleolus small nucleolar ribonucleoprotein complex	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing	snoRNA binding
VAC14	fungal-type vacuole membrane vacuole	vacuole inheritance phospholipid metabolic process	enzyme activator activity
VPS5	endosome retromer complex cytosol	protein retention in Golgi apparatus retrograde transport, endosome to Golgi	protein transporter activity phosphatidylinositol-3-phosphate binding
YJL017W

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation release factor complex	1.2783E-5	23	2	2	6292
protein complex	1.0291E-3	23	1137	11	6292
macromolecular complex	1.7928E-3	23	1635	13	6292
nuclear envelope	5.3606E-3	23	199	4	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
protein complex disassembly	1.0256E-5	23	39	4	6292
cellular protein complex disassembly	1.0256E-5	23	39	4	6292
cellular macromolecular complex disassembly	1.1368E-5	23	40	4	6292
macromolecular complex disassembly	1.1368E-5	23	40	4	6292
cellular component disassembly	1.6724E-5	23	44	4	6292
translational termination	3.5318E-4	23	8	2	6292
termination of RNA polymerase II transcription, poly(A)-independent	4.5308E-4	23	9	2	6292
macromolecular complex subunit organization	1.4152E-3	23	357	6	6292
cellular macromolecular complex subunit organization	2.0783E-3	23	259	5	6292
termination of RNA polymerase II transcription	2.1048E-3	23	19	2	6292
transcription termination	2.5734E-3	23	21	2	6292
pteridine and derivative biosynthetic process	3.6554E-3	23	1	1	6292
folic acid biosynthetic process	3.6554E-3	23	1	1	6292
nitrogenous compound catabolic process	3.6554E-3	23	1	1	6292
anaerobic purine catabolic process	3.6554E-3	23	1	1	6292
acetate biosynthetic process from carbon monoxide	3.6554E-3	23	1	1	6292
cellular component organization	4.8117E-3	23	1582	12	6292
purine base catabolic process	7.2981E-3	23	2	1	6292
nucleobase catabolic process	7.2981E-3	23	2	1	6292
pteridine and derivative metabolic process	7.2981E-3	23	2	1	6292
folic acid metabolic process	7.2981E-3	23	2	1	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation release factor activity	3.8264E-5	23	3	2	6292
translation termination factor activity	7.6359E-5	23	4	2	6292
translation factor activity, nucleic acid binding	5.1255E-4	23	44	3	6292
binding	3.0991E-3	23	1294	11	6292
translation release factor activity, codon specific	3.6554E-3	23	1	1	6292
methenyltetrahydrofolate cyclohydrolase activity	7.2981E-3	23	2	1	6292
methylenetetrahydrofolate dehydrogenase (NADP+) activity	7.2981E-3	23	2	1	6292
formate-tetrahydrofolate ligase activity	7.2981E-3	23	2	1	6292
nucleic acid binding	7.7573E-3	23	666	7	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis