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A process by which a protein is transported to, or maintained in, a location within the nucleus. A process by which a protein is transported to, or maintained in, a location within an organelle. The aggregation, arrangement and bonding together of the nuclear localization signal of a protein with nuclear envelope proteins such as importins. The directed movement of substances into the nucleus. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. The directed movement of a protein from the cytoplasm to the nucleus. The directed movement of proteins into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear membrane. The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. The directed movement of a transcription factor from the cytoplasm to the nucleus. The directed movement of a heterogeneous nuclear ribonucleoprotein complex from the cytoplasm into the nucleus, across the nuclear membrane. The directed movement of molecules between the nucleus and the cytoplasm. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane. The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. The directed movement of proteins into a cell or organelle. Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. The disaggregation of a protein complex composed of the nuclear localization sequence and the importin alpha, and importin beta proteins. The vectorial transfer of a protein from the cytoplasm into the nucleus, through the nuclear pore and across the nuclear envelope.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein import into nucleus
Acc: GO:0006606
Aspect: Biological Process
Desc: The directed movement of a protein from the cytoplasm to the nucleus.
Synonyms:
  • protein targeting to nucleus
  • protein transport from cytoplasm to nucleus
  • protein import into cell nucleus
  • protein nucleus import
Proteins in PDR annotated with:
   This term: 180 [Search]
   Term or descendants: 439 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006606 - protein import into nucleus (interactive image map)
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Created and Maintained by: Michael Riffle