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Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules. Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA-intron endonuclease activity
Acc: GO:0000213
Aspect: Molecular Function
Desc: Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
Synonyms:
  • tRNA splicing endonuclease activity
  • tRNA-splicing endonuclease activity
  • transfer ribonucleate intron endoribonuclease activity
  • splicing endonuclease activity
  • transfer splicing endonuclease activity
  • tRNATRPintron endonuclease activity
  • tRNA-intron endoribonuclease activity
Proteins in PDR annotated with:
   This term: 28 [Search]
   Term or descendants: 28 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000213 - tRNA-intron endonuclease activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle