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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BLM10
  • nucleus
  • proteasome core complex
  • proteasome complex
  • protein catabolic process
  • proteasome assembly
  • proteasome activator activity
  • CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • CIN1
  • cellular_component
  • post-chaperonin tubulin folding pathway
  • beta-tubulin binding
  • ERG13
  • endoplasmic reticulum
  • ergosterol biosynthetic process
  • hydroxymethylglutaryl-CoA synthase activity
  • GUS1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • glutamyl-tRNA aminoacylation
  • glutamate-tRNA ligase activity
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • HOS2
  • histone deacetylase complex
  • regulation of transcription, DNA-dependent
  • chromatin organization
  • histone deacetylation
  • negative regulation of meiosis
  • NAD-dependent histone deacetylase activity
  • NAD-independent histone deacetylase activity
  • HOS4
  • histone deacetylase complex
  • histone deacetylation
  • negative regulation of meiosis
  • NAD-dependent histone deacetylase activity
  • NAD-independent histone deacetylase activity
  • IML1
  • fungal-type vacuole membrane
  • biological_process
  • molecular_function
  • KAP95
  • cytoplasm
  • nuclear pore
  • protein import into nucleus
  • nuclear pore complex assembly
  • protein transmembrane transporter activity
  • KEL1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • regulation of cell shape
  • negative regulation of exit from mitosis
  • cell morphogenesis
  • cytogamy
  • plasma membrane fusion
  • molecular_function
  • LTE1
  • cellular bud
  • vesicle-mediated transport
  • regulation of exit from mitosis
  • response to drug
  • mitotic cell cycle spindle orientation checkpoint
  • guanyl-nucleotide exchange factor activity
  • MYO5
  • actin cortical patch
  • response to salt stress
  • bipolar cellular bud site selection
  • response to osmotic stress
  • cellular cell wall organization
  • endocytosis
  • exocytosis
  • microfilament motor activity
  • PFK1
  • 6-phosphofructokinase complex
  • cytoplasm
  • mitochondrion
  • glycolysis
  • 6-phosphofructokinase activity
  • PPH21
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • PPH22
  • condensed nuclear chromosome, centromeric region
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • PRE1
  • nucleus
  • proteasome core complex, beta-subunit complex
  • ascospore formation
  • response to stress
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE10
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE2
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE4
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE5
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE6
  • mitochondrion
  • proteasome core complex, alpha-subunit complex
  • cytosol
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE7
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE8
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE9
  • proteasome core complex, alpha-subunit complex
  • filamentous growth
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PUP1
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PUP2
  • proteasome core complex, alpha-subunit complex
  • ascospore formation
  • response to stress
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PUP3
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RRD2
  • cytosol
  • cell fraction
  • response to osmotic stress
  • mitotic spindle organization in nucleus
  • protein phosphatase type 2A regulator activity
  • RTS1
  • nucleus
  • condensed nuclear chromosome, centromeric region
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • protein phosphatase type 2A complex
  • protein amino acid dephosphorylation
  • meiotic sister chromatid cohesion, centromeric
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • RTS3
  • nucleus
  • cytoplasm
  • protein phosphatase type 2A complex
  • protein amino acid dephosphorylation
  • molecular_function
  • SCL1
  • mitochondrion
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • SET3
  • histone deacetylase complex
  • histone deacetylation
  • negative regulation of meiosis
  • NAD-dependent histone deacetylase activity
  • NAD-independent histone deacetylase activity
  • SIF2
  • nucleus
  • histone deacetylase complex
  • negative regulation of transcription from RNA polymerase II promoter
  • histone deacetylation
  • chromatin silencing at telomere
  • negative regulation of meiosis
  • transcription corepressor activity
  • NAD-dependent histone deacetylase activity
  • NAD-independent histone deacetylase activity
  • SNT1
  • histone deacetylase complex
  • histone deacetylation
  • negative regulation of meiosis
  • NAD-dependent histone deacetylase activity
  • NAD-independent histone deacetylase activity
  • SRP1
  • nucleus
  • cytoplasm
  • nucleocytoplasmic transport
  • protein transmembrane transporter activity
  • TDH2
  • lipid particle
  • fungal-type cell wall
  • cytoplasm
  • mitochondrion
  • gluconeogenesis
  • glycolysis
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
  • TDH3
  • lipid particle
  • fungal-type cell wall
  • cytoplasm
  • mitochondrion
  • gluconeogenesis
  • glycolysis
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
  • TEF4
  • mitochondrion
  • ribosome
  • eukaryotic translation elongation factor 1 complex
  • translational elongation
  • translation elongation factor activity
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • YBL104C
  • cytoplasm
  • biological_process
  • molecular_function
  • YOR1
  • plasma membrane
  • response to drug
  • telomere maintenance
  • transport
  • xenobiotic-transporting ATPase activity
  • YRA1
  • transcription export complex
  • mRNA export from nucleus
  • RNA binding
  • ZDS1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • nuclear pore
  • mRNA export from nucleus
  • chromatin silencing
  • cell aging
  • protein binding
  • ZDS2
  • nucleus
  • chromatin silencing at rDNA
  • cell aging
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome core complex 1.1513E-29 45 16 14 6292
    proteasome complex 3.9904E-20 45 48 14 6292
    proteasome core complex, alpha-subunit complex 5.8779E-16 45 7 7 6292
    protein complex 7.4113E-15 45 1137 32 6292
    protein phosphatase type 2A complex 9.4739E-14 45 6 6 6292
    proteasome core complex, beta-subunit complex 6.5965E-13 45 7 6 6292
    macromolecular complex 2.6718E-10 45 1635 32 6292
    protein serine/threonine phosphatase complex 1.1057E-9 45 17 6 6292
    histone deacetylase complex 4.5534E-7 45 23 5 6292
    chromatin remodeling complex 6.462E-5 45 99 6 6292
    cellular bud tip 6.8416E-4 45 57 4 6292
    cellular bud 1.0693E-3 45 166 6 6292
    cellular bud neck 2.1222E-3 45 129 5 6292
    site of polarized growth 6.5883E-3 45 168 5 6292
    intracellular part 6.8423E-3 45 4938 42 6292
    nucleoplasm part 7.4648E-3 45 245 6 6292
    cell part 8.3293E-3 45 5397 44 6292
    cell 8.4505E-3 45 5399 44 6292
    intracellular 8.709E-3 45 4975 42 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    negative regulation of cell cycle process 6.9163E-15 45 32 10 6292
    regulation of cell cycle process 5.7097E-12 45 81 11 6292
    protein metabolic process 6.6421E-12 45 1136 29 6292
    cellular protein metabolic process 1.317E-11 45 1074 28 6292
    protein catabolic process 2.2222E-11 45 189 14 6292
    modification-dependent protein catabolic process 2.9834E-11 45 156 13 6292
    ubiquitin-dependent protein catabolic process 2.9834E-11 45 156 13 6292
    proteolysis involved in cellular protein catabolic process 3.8045E-11 45 159 13 6292
    modification-dependent macromolecule catabolic process 5.6424E-11 45 164 13 6292
    cellular protein catabolic process 9.5861E-11 45 171 13 6292
    proteolysis 3.1607E-10 45 188 13 6292
    negative regulation of meiosis 8.2068E-10 45 8 5 6292
    regulation of cell cycle 1.162E-9 45 131 11 6292
    macromolecule catabolic process 7.8346E-9 45 294 14 6292
    negative regulation of cellular process 1.0579E-8 45 250 13 6292
    negative regulation of biological process 1.222E-8 45 253 13 6292
    catabolic process 1.8486E-8 45 496 17 6292
    cellular macromolecule catabolic process 2.1355E-8 45 265 13 6292
    protein amino acid dephosphorylation 3.174E-8 45 28 6 6292
    M phase 7.3633E-8 45 294 13 6292
    dephosphorylation 3.0333E-7 45 40 6 6292
    regulation of meiosis 3.5825E-7 45 22 5 6292
    regulation of meiotic cell cycle 3.5825E-7 45 22 5 6292
    spindle checkpoint 7.1136E-7 45 25 5 6292
    mitotic cell cycle spindle checkpoint 7.1136E-7 45 25 5 6292
    histone deacetylation 1.0695E-6 45 27 5 6292
    cell cycle phase 1.2765E-6 45 376 13 6292
    mitotic cell cycle checkpoint 1.2951E-6 45 28 5 6292
    protein amino acid deacetylation 1.5566E-6 45 29 5 6292
    primary metabolic process 2.9563E-6 45 2896 36 6292
    cellular catabolic process 3.8696E-6 45 415 13 6292
    macromolecule metabolic process 4.0795E-6 45 2349 32 6292
    cell cycle process 4.3882E-6 45 490 14 6292
    post-translational protein modification 4.845E-6 45 357 12 6292
    cellular macromolecule metabolic process 8.5229E-6 45 2285 31 6292
    regulation of mitotic cell cycle 9.5916E-6 45 71 6 6292
    cell cycle 9.8278E-6 45 525 14 6292
    negative regulation of nuclear division 1.2506E-5 45 21 4 6292
    negative regulation of mitotic metaphase/anaphase transition 1.2506E-5 45 21 4 6292
    mitotic cell cycle spindle assembly checkpoint 1.2506E-5 45 21 4 6292
    negative regulation of mitosis 1.2506E-5 45 21 4 6292
    spindle assembly checkpoint 1.2506E-5 45 21 4 6292
    negative regulation of cell cycle 1.5206E-5 45 22 4 6292
    regulation of mitotic metaphase/anaphase transition 2.5887E-5 45 25 4 6292
    covalent chromatin modification 3.3144E-5 45 88 6 6292
    histone modification 3.3144E-5 45 88 6 6292
    metabolic process 3.4196E-5 45 3157 36 6292
    regulation of nuclear division 4.7599E-5 45 29 4 6292
    negative regulation of organelle organization 4.7599E-5 45 29 4 6292
    negative regulation of cellular component organization 4.7599E-5 45 29 4 6292
    regulation of mitosis 4.7599E-5 45 29 4 6292
    cell cycle checkpoint 5.1485E-5 45 58 5 6292
    budding cell bud growth 9.0549E-5 45 34 4 6292
    reproduction of a single-celled organism 1.2597E-4 45 217 8 6292
    mitotic metaphase/anaphase transition 1.2695E-4 45 37 4 6292
    protein modification process 1.3778E-4 45 499 12 6292
    cellular process 1.6127E-4 45 4426 42 6292
    cellular metabolic process 1.6239E-4 45 3033 34 6292
    regulation of cellular component organization 1.7719E-4 45 75 5 6292
    M phase of mitotic cell cycle 2.6788E-4 45 128 6 6292
    negative regulation of exit from mitosis 2.974E-4 45 4 2 6292
    cell budding 4.1669E-4 45 90 5 6292
    asexual reproduction 4.1669E-4 45 90 5 6292
    macromolecule modification 4.7165E-4 45 569 12 6292
    regulation of organelle organization 4.8126E-4 45 52 4 6292
    exit from mitosis 7.0442E-4 45 25 3 6292
    glycolysis 7.0442E-4 45 25 3 6292
    regulation of exit from mitosis 7.0442E-4 45 25 3 6292
    meiosis 8.8222E-4 45 160 6 6292
    M phase of meiotic cell cycle 8.8222E-4 45 160 6 6292
    regulation of cellular process 9.0956E-4 45 796 14 6292
    meiotic cell cycle 1.0038E-3 45 164 6 6292
    chromatin modification 1.138E-3 45 168 6 6292
    regulation of biological process 1.2842E-3 45 824 14 6292
    actin filament organization 1.3321E-3 45 68 4 6292
    reproduction 1.9838E-3 45 328 8 6292
    mitotic cell cycle 2.0037E-3 45 255 7 6292
    chromatin organization 2.9843E-3 45 203 6 6292
    cell division 3.5294E-3 45 145 5 6292
    growth 3.5294E-3 45 145 5 6292
    glucose catabolic process 3.6895E-3 45 44 3 6292
    hexose catabolic process 5.0065E-3 45 49 3 6292
    phosphorus metabolic process 5.3983E-3 45 229 6 6292
    phosphate metabolic process 5.3983E-3 45 229 6 6292
    mitosis 6.2402E-3 45 104 4 6292
    monosaccharide catabolic process 6.5748E-3 45 54 3 6292
    nuclear division 6.6723E-3 45 106 4 6292
    histone H3-K79 methylation 7.1519E-3 45 1 1 6292
    pore complex assembly 7.1519E-3 45 1 1 6292
    nuclear pore complex assembly 7.1519E-3 45 1 1 6292
    meiotic sister chromatid cohesion, centromeric 7.1519E-3 45 1 1 6292
    alcohol catabolic process 7.6414E-3 45 57 3 6292
    actin cytoskeleton organization 8.3407E-3 45 113 4 6292
    organelle fission 8.3407E-3 45 113 4 6292
    actin filament-based process 9.4071E-3 45 117 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endopeptidase activity 1.7326E-17 45 54 13 6292
    peptidase activity, acting on L-amino acid peptides 4.4852E-14 45 95 13 6292
    NAD-independent histone deacetylase activity 3.094E-10 45 7 5 6292
    peptidase activity 4.113E-10 45 192 13 6292
    hydrolase activity 9.7881E-10 45 911 24 6292
    NAD-dependent protein deacetylase activity 1.8367E-9 45 9 5 6292
    NAD-dependent histone deacetylase activity 1.8367E-9 45 9 5 6292
    protein phosphatase type 2A regulator activity 1.361E-6 45 4 3 6292
    protein deacetylase activity 2.5978E-6 45 32 5 6292
    histone deacetylase activity 2.5978E-6 45 32 5 6292
    deacetylase activity 4.1216E-6 45 35 5 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2.0289E-5 45 48 5 6292
    protein serine/threonine phosphatase activity 3.0434E-5 45 26 4 6292
    catalytic activity 3.0811E-5 45 2150 29 6292
    glyceraldehyde-3-phosphate dehydrogenase activity 1.4938E-4 45 3 2 6292
    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 1.4938E-4 45 3 2 6292
    phosphoprotein phosphatase activity 2.2991E-4 45 43 4 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2.4034E-4 45 80 5 6292
    protein phosphatase regulator activity 5.4786E-4 45 23 3 6292
    phosphatase regulator activity 5.4786E-4 45 23 3 6292
    macromolecule transmembrane transporter activity 1.7442E-3 45 9 2 6292
    protein transmembrane transporter activity 1.7442E-3 45 9 2 6292
    phosphatase activity 3.2989E-3 45 87 4 6292
    phosphoric ester hydrolase activity 5.8272E-3 45 102 4 6292
    hydroxymethylglutaryl-CoA synthase activity 7.1519E-3 45 1 1 6292
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7.9168E-3 45 19 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle