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Protein Overview: SNT1

General Information:
Name(s) found: SNT1 / YCR033W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1226 amino acids

    Gene Ontology:
    Cellular Component: histone deacetylase complex [IPILink to PubMed article]
    Biological Process: histone deacetylation [IDALink to PubMed article][IPILink to PubMed article]
    negative regulation of meiosis [IPILink to PubMed article]
    Molecular Function: NAD-dependent histone deacetylase activity [IPILink to PubMed article]
    NAD-independent histone deacetylase activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYPPPTRRL GDKKRYHYSN NPNRRHPSAV YSKNSFPKSS NNGFVSSPTA DNSTNPSVTP  60
   61 STASVPLPTA APGSTFGIEA PRPSRYDPSS VSRPSSSSYS STRKIGSRYN PDVERSSSTT 120
  121 SSTPESMNTS TITHTNTDIG NSRYSRKTMS RYNPQSTSST NVTHFPSALS NAPPFYVANG 180
  181 SSRRPRSMDD YSPDVTNKLE TNNVSSVNNN SPHSYYSRSN KWRSIGTPSR PPFDNHVGNM 240
  241 TTTSNTNSIH QREPFWKANS TTILKSTHSQ SSPSLHTKKF HDANKLDKPE ASVKVETPSK 300
  301 DETKAISYHD NNFPPRKSVS KPNAPLEPDN IKVGEEDALG KKEVHKSGRE IAKEHPTPVK 360
  361 MKEHDELEAR AKKVSKINID GKQDEIWTTA KTVASAVEVS KESQKELTRS VERKESPEIR 420
  421 DYERAYDPKA LKTDVTKLTV DNDNKSYEEP LEKVEGCIFP LPKAETRLWE LKNQKRNKII 480
  481 SEQKYLLKKA IRNFSEYPFY AQNKLIHQQA TGLILTKIIS KIKKEEHLKK INLKHDYFDL 540
  541 QKKYEKECEI LTKLSENLRK EEIENKRKEH ELMEQKRREE GIETEKEKSL RHPSSSSSSR 600
  601 RRNRADFVDD AEMENVLLQI DPNYKHYQAA ATIPPLILDP IRKHSYKFCD VNNLVTDKKL 660
  661 WASRILKDAS DNFTDHEHSL FLEGYLIHPK KFGKISHYMG GLRSPEECVL HYYRTKKTVN 720
  721 YKQLLIDKNK KRKMSAAAKR RKRKERSNDE EVEVDESKEE STNTIEKEEK SENNAEENVQ 780
  781 PVLVQGSEVK GDPLGTPEKV ENMIEQRGEE FAGELENAER VNDLKRAHDE VGEESNKSSV 840
  841 IETNNGVQIM DPKGAVQNGY YPEETKELDF SLENALQRKK HKSAPEHKTS YWSVRESQLF 900
  901 PELLKEFGSQ WSLISEKLGT KSTTMVRNYY QRNAARNGWK LLVDETDLKR DGTSSESVQQ 960
  961 SQILIQPERP NINAYSNIPP QQRPALGYFV GQPTHGHNTS ISSIDGSIRP FGPDFHRDTF1020
 1021 SKISAPLTTL PPPRLPSIQF PRSEMAEPTV TDLRNRPLDH IDTLADAASS VTNNQNFSNE1080
 1081 RNAIDIGRKS TTISNLLNNS DRSMKSSFQS ASRHEAQLED TPSMNNIVVQ EIKPNITTPR1140
 1141 SSSISALLNP VNGNGQSNPD GRPLLPFQHA ISQGTPTFPL PAPRTSPISR APPKFNFSND1200
 1201 PLAALAAVAS APDAMSSFLS KKENNN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CPR1 HOS2 HOS4 SET3 SIF2 SNT1
    View Details Krogan NJ, et al. (2006) AKL1 HOS4 HST1 RFM1 SET3 SIF2 SNT1 SUM1
    View Details Gavin AC, et al. (2006) CPR1 HOS2 HOS4 SET3 SIF2 SNT1
    View Details Gavin AC, et al. (2002) BLM10 CDC55 CIN1 CPR1 ERG13 GUS1 HHF1, HHF2 HOS2 HOS4 IML1 KAP95 KEL1 LTE1 MYO5 PFK1 PPH21 PPH22 PRE1 PRE10 PRE2 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP1 PUP2 PUP3 RRD2 RTS1 RTS3 RVB2 SCL1 SET3 SIF2 SNF2 SNT1 SRP1 TDH2 TDH3 TEF4 TPD3 YBL104C YOR1 YRA1 ZDS1 ZDS2
    View Details Ho Y, et al. (2002) AVT2 HOS4 SIF2 SNT1 TFP1 TRM3 UTP21 YMR155W YRF1-3, YRF1-7 ZDS2
    View Details Qiu et al. (2008) HDA1 HDA2 HDA3 HOS1 HOS2 HOS4 HST1 RPD3 SDS3 SET3 SIF2 SIN3 SNT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SNT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..551] MSA 40.291998 View MSA. No confident structure predictions are available.
    2 View Details [552..656] deduced N/A No confident structure predictions are available.
    3 View Details [657..779] Pfam 11.119186 Myb-like DNA-binding domain No confident structure predictions are available.
    4 View Details [780..875] deduced N/A No confident structure predictions are available.
    5 View Details [876..968] Pfam 10.49485 Myb-like DNA-binding domain No confident structure predictions are available.
    6 View Details [969..1226] deduced N/A No confident structure predictions are available.
    7 View Details [831..965] PSI-BLAST 38.69897 No description for 2iw5B was found.
    8 View Details [966..1226] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle