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Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of anti-apoptosis. Any process that stops, prevents or reduces the frequency, rate or extent of sulfur utilization. Any process that stops, prevents or reduces the frequency, rate or extent of phosphorus utilization. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of locomotion of a cell or organism. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that decreases the frequency, rate or extent of border cell delamination. Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. null Any process that stops, prevents or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that reduces the levels of viral proteins in a cell. Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen utilization. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that modulates the frequency, rate or extent of any biological process, quality or function. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. Any process that stops, prevents or reduces the frequency, rate or extent of a multi-organism process, a process by which an organism has an effect on another organism of the same or different species. Any process that stops, prevents or reduces the frequency, rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts. Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process. Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. Any process that stops, prevents or reduces the frequency, rate or extent of cell killing. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of biological process
Acc: GO:0048519
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
Synonyms:
  • negative regulation of physiological process
  • downregulation of biological process
  • inhibition of biological process
  • down-regulation of biological process
  • GO:0043118
  • down regulation of biological process
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 5988 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048519 - negative regulation of biological process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle