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Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice. A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body. Structure adjacent to the plaques of the spindle pole body. A cytoplasmic structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm. One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope. One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus. The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome. Structure between the central and outer plaques of the spindle pole body. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: spindle pole body
Acc: GO:0005816
Aspect: Cellular Component
Desc: The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
Proteins in PDR annotated with:
   This term: 298 [Search]
   Term or descendants: 316 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005816 - spindle pole body (interactive image map)
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