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Protein Overview: DBP6

General Information:
Name(s) found: DBP6 / YNR038W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 629 amino acids

    Gene Ontology:
    Cellular Component: nuclear outer membrane [IMPLink to PubMed article]
    nucleolus [IDALink to PubMed article]
    preribosome, large subunit precursor [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    ribosomal large subunit assembly [IMPLink to PubMed article]
    Molecular Function: ATP-dependent RNA helicase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFASRFDPSQ LTAPAASAPE GIVGTTPPAI VPLKRQATES DNEEYGSHQD SDESSNSSSE  60
   61 EDEDRMQVDY GASEEDSSEV EEEESKPSTH STVLSRFKQT VSLQERLGAS DIAESKEDEG 120
  121 IEDEAASTHQ LKQIPQPEFV KNPMNLNTNS LQFKSTGWLN TEKIYYDNSL IKPFSDYANE 180
  181 LEAKLLQNIC KNFSTNTFPI QSIILDSILP VLNFTLNVSK RNFTRRIGDI LVNAATGSGK 240
  241 TLAYSIPIVQ TLFKRQINRL RCIIIVPTKL LINQVYTTLT KLTQGTSLIV SIAKLENSLK 300
  301 DEHKKLSNLE PDILITTPGR LVDHLNMKSI NLKNLKFLII DEADRLLNQS FQGWCPKLMS 360
  361 HLKTDKLDTL PGNVIKMIFS ATLTTNTEKL NGLNLYKPKL FLKQTDKLYQ LPNKLNEFNI 420
  421 NIPTAKSVYK PLILLYSICQ FMAHSPIAAK ILIFVKSNES SIRLSKLLQL ICESRSQSSV 480
  481 LKNLQNLAVS INSVNSNNSK AENKKIVANF SHHSESAGIT ILITTDIMSR GIDINDITQV 540
  541 INYDPPMSSQ QYVHRVGRTA RANELGSAYN LLVGRGERTF FDDLNKDLDR DGKSVQPLEL 600
  601 DFTLLESDSE LYTSSLESLK NYHNNTAQA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BUD22 CIC1 DBP6 EFG1 FRE3 GIS2 HAS1 MAK21 NIP7 NOB1 NOC2 NOC3 NOP1 NOP2 NOP8 PUS7 RRP5 RSA3 SBP1 SFA1 SSQ1 YGR272C YMR034C YRF1-8, YRF1-5, ...
    View Details Qiu et al. (2008) BRR2 DBP10 DBP3 DBP6 DBP7 DBP8 DBP9 DHR2 DRS1 ECM16 ENP1 FAL1 HAS1 HCA4 KRE33 MAK21 MAK5 MTR4 NOC2 NOC3 NOC4 NOP12 NOP4 NSR1 NUG1 PRP43 PWP2 RCL1 RNT1 ROK1 RRP3 RSA3 SPB4 UTP13 UTP4 UTP6

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen APC5 DBP6 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data DBP6 and NOP56 Huh WK, et al. (2003)
    View Data DBP6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 4.581996 View MSA. No confident structure predictions are available.
    2 View Details [170..410] PSI-BLAST 395.9897 Putative DEAD box RNA helicase
    3 View Details [411..629] PSI-BLAST 395.9897 Putative DEAD box RNA helicase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle