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Protein Overview: CMR1

General Information:
Name(s) found: CMR1 / YDL156W [SGD]
Description(s) found:
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  • gi|74676615|sp|Q12510.1|YD156_YEAST RecName: Full=WD repeat-containing protein YDL156W [NCBI NR]
  • gi|6320045|ref|NP_010125.1| Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; Ydl156wp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S67704 hypothetical protein YDL156w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1431247|emb|CAA98730.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1321948|emb|CAA66335.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • WD repeat-containing protein YDL156W OS=Saccharomyces cerevisiae GN=YDL156W PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function localised to cytoplasm and nucleus [mips]
  • Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus [SGD]
  • YDL156W, Chr IV from 174919-176487 [yeast_orfs2]
  • Chr IV from 174919-176487 [yeastorf3.fasta]
  • >Q12510 (Q12510) Chromosome IV reading frame ORF YDL156W [4932.FASTACCERV.txt]
  • YDL156W SGDID:S0002315, Chr IV from 174919-176487, Uncharacterized ORF [yeastflysequest.fasta]
  • Ydl156wp [Saccharomyces cerevisiae]gi|1431247|emb|CAA98730.1| unnamed protein product [Saccharomyces cerevisiae]gi|1321948|emb|CAA66335.1| unnamed protein product [Saccharomyces cerevisiae]gi|2131348|pir||S67704 hypothetical protein YDL156w - yeast (Sa [nrdb_11152004_Chlamydomonas]
  • (Q12510) S.cerevisiae chromosome IV reading frame ORF YDL156w (D1536) [cerv4932.FASTAC]
  • YDL156W SGDID:S000002315, Chr IV from 174919-176487, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YDL156W SGDID:S000002315, Chr IV from 174919-176487, Uncharacterized ORF, "Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucle [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • hypothetical protein; Ydl156wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • WD repeat protein YDL156W [nr-271106-contam.fasta]
  • YDL156W SGDID:S000002315, Chr IV from 174919-176487, Uncharacterized ORF, "Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • WD repeat-containing protein YDL156W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDL156W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YDL156W SGDID:S000002315, Chr IV from 174918-176486, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; potential regulatory target of Mbp1p, which binds to the YDL156W promoter region" [yeast-030211-contam.fasta]
  • CMR1 SGDID:S000002315, Chr IV from 174918-176486, Genome Release 64-2-1, Verified ORF, "DNA-binding protein with preference for UV-damaged DNA; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; potential regulatory target of Mbp1p, which binds to the promoter region; co-localizes with Hos2p in nuclear foci in response to DNA damage by MMS" [20141208_orf_trans.fasta]
  • DNA damage-binding protein CMR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CMR1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELTEFQKK RLENIKRNND LLKKLHLSGV ASQIKHEAGV LEKSRAPAKK KQKTTNTRAT  60
   61 KSASPTLPTR RSRRLRGESA DDVKGIPNVN DNQLLKMGSP DGQDKNFIDA IKEKPVIGDV 120
  121 KLSDLIKDED ESALLEKFKR FNNGNFSSGD FFEEIKKRQG DVTGMDEFDL DLYDVFQPNE 180
  181 IKITYERISA TYFHPAMEKK LIIAGDTSGT VGFWNVRDEP LADSEEDRME EPDITRVKLF 240
  241 TKNVGRIDCF PADTSKILLT SYDGSIRSVH LNNLQSEEVL TLKNEYDDSL GISDCQFSYE 300
  301 NPNVLFLTTL GGEFTTFDTR VKKSEYNLRR LADKKIGSMA INPMRPYEIA TGSLDRTLKI 360
  361 WDTRNLVKKP EWSQYEDYPS HEIVSTYDSR LSVSAVSYSP TDGTLVCNGY DDTIRLFDVK 420
  421 SRDHLSAKLE PKLTIQHNCQ TGRWTSILKA RFKPNKNVFA IANMKRAIDI YNSEGQQLAH 480
  481 LPTATVPAVI SWHPLRNWIA GGNSSGKIFL FTDDSGTIKQ EE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CMR1 POB3 RFA1
    View Details Krogan NJ, et al. (2006) ABF2 ARG82 CKI1 CMR1 HHF1, HHF2 HTA1 HTA2 HTB1 HTB2 NUP188 PPH3 PSY2 PSY4 RRD1 SLX5 SLX8 SPT5 STP1 TOP2
    View Details Gavin AC, et al. (2002) CMR1 DNA2 HDA1 HDA2 HDA3 HSC82 KAP95 LCD1 MEC1 MGM101 MLH1 MPH1 MSH2 MSH3 MSH6 OLA1 PGK1 PMS1 PRO2 RAD16 RAD52 RFA1 RFA2 RFA3 RIM1 RNH1 RSC8 RVB2 SGS1 SHS1 TIF1, TIF2 TOP3 VAS1 VPS1 YHR122W
    View Details Ho Y, et al. (2002) CCT2 CCT3 CMR1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CMR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..522] PSI-BLAST 70.221849 Tup1, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.83286470399158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.2886835964948 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.0160811807475 bayes_pls_golite062009
  • DNA binding
    		•  0.561578774129549 bayes_pls_golite062009
  • protein binding
    		•  0.522364360354028 bayes_pls_golite062009
  • transcription factor activity
    		•  0.00445255815744083 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle