Protein Overview: RPL21A

General Information:
Name(s) found:	RPL21A / YBR191W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6319668\|ref\|NP_009750.1\| Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein; Rpl21ap [Saccharomyces cerevisiae] [NCBI NR] gi\|575917\|gb\|AAB60284.1\| homolog of rat ribosomal protein L21 [Saccharomyces cerevisiae] [NCBI NR] gi\|536555\|emb\|CAA85153.1\| URP1A [Saccharomyces cerevisiae] [NCBI NR] gi\|400988\|sp\|Q02753.1\|RL21A_YEAST RecName: Full=60S ribosomal protein L21-A [NCBI NR] pir\|\|S28921 ribosomal protein L21.e.A, cytosolic - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|173155\|gb\|AAA35202.1\| ribosomal protein [Saccharomyces cerevisiae] [NCBI NR] 60S ribosomal protein L21-A OS=Saccharomyces cerevisiae GN=RPL21A PE=1 SV=1 [Swiss-Prot] (Q02753) 60S ribosomal protein L21-A [Swiss-Prot] RPL21A Ribosomal protein L21.e [mips] Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein [SGD] RPL21A, Chr II from 606228-606238,606627-607098 [yeast_orfs2] Chr II from 606228-606238,606627-607098 [yeastorf3.fasta] Chr II from 606227-606237,606626-607097 [yeastorf4.fasta] Chr II from 606225-606235,606624-607095 [yeastorf5.fasta] RPL21A SGDID:S0000395, Chr II from 606227-606237,606626-607097, Verified ORF [yeastflysequest.fasta] RPL21A SGDID:S0000395, Chr II from 606265-606275,606664-607135, Verified ORF [10112005cervSGD.fasta] Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein [Saccharomyces cerevisiae]gi\|536555\|emb\|CAA85153.1\| URP1A [Saccharomyces cerevisiae]gi\|575917\|gb\|AAB60284.1\| homolog of r [nrdb_11152004_Chlamydomonas] RPL21A SGDID:S000000395, Chr II from 606265-606275,606664-607135, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein; Rpl21ap [Saccharomyces cerevisiae] [nr-271106-contam.fasta] 60S ribosomal protein L21-A [nr-271106-contam.fasta] URP1A [Saccharomyces cerevisiae] [nr-271106-contam.fasta] homolog of rat ribosomal protein L21 [nr-271106-contam.fasta] ribosomal protein [nr-271106-contam.fasta] [chemostatdb.fasta] 60S ribosomal protein L21-A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPL21A PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] RPL21A SGDID:S000000395, Chr II from 606270-606280,606669-607140, Genome Release 64-1-1, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" [yeast-030211-contam.fasta] RPL21A SGDID:S000000395, Chr II from 606270-606280,606669-607140, Genome Release 64-2-1, Verified ORF, "Ribosomal 60S subunit protein L21A; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21A has a paralog, RPL21B, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR947\|c0_g1_i1\|g.609 ORF TR947\|c0_g1_i1\|g.609 TR947\|c0_g1_i1\|m.609 type:complete len:161 (+) TR947\|c0_g1_i1:45-527(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR5447\|c1_g2_i2\|g.3859 ORF TR5447\|c1_g2_i2\|g.3859 TR5447\|c1_g2_i2\|m.3859 type:complete len:161 (+) TR5447\|c1_g2_i2:71-553(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YBR191W SGDID:S000000395, Chr II from 606270-606280,606669-607140, Genome Release 64-1-1, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_4774\|g.3555 ORF asmbl_4774\|g.3555 asmbl_4774\|m.3555 type:complete len:161 (+) asmbl_4774:173-655(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_4768\|g.3703 ORF asmbl_4768\|g.3703 asmbl_4768\|m.3703 type:complete len:161 (+) asmbl_4768:68-550(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_5098\|g.3116 ORF ID=asmbl_5098\|g.3116 ID=asmbl_5098\|m.3116 type:complete len:161 (+) ID=asmbl_5098:173-655(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_4773\|g.3054 ORF ID=asmbl_4773\|g.3054 ID=asmbl_4773\|m.3054 type:complete len:161 (+) ID=asmbl_4773:68-550(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	160 amino acids
Gene Ontology:
Cellular Component:	ribonucleoprotein complex [IEA] cytoplasm [IEA] cytosolic large ribosomal subunit [TAS] ribosome [IEA] intracellular [IEA]
Biological Process:	translation [TAS]
Molecular Function:	structural constituent of ribosome [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKSHGYRSR TRYMFQRDFR KHGAVHLSTY LKVYKVGDIV DIKANGSIQK GMPHKFYQGK  60
   61 TGVVYNVTKS SVGVIINKMV GNRYLEKRLN LRVEHIKHSK CRQEFLERVK ANAAKRAEAK 120
  121 AQGVAVQLKR QPAQPRESRI VSTEGNVPQT LAPVPYETFI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ISA2 LYS21 NHP6A PUF4 RPL11B RPL12B, RPL12A RPL16A RPL16B RPL17A RPL17B RPL18A, RPL18B RPL1A, RPL1B RPL20A RPL21A RPL24A RPL26A RPL29 RPL2A, RPL2B RPL3 RPL30 RPL32 RPL36A RPL42B, RPL42A RPL43B, RPL43A RPL4A RPL6A RPL8B RPL9A RPS11A, RPS11B RPS14A RPS16B, RPS16A RPS17B RPS1A RPS2 RPS22A RPS23B, RPS23A RPS26A RPS26B RPS3 RPS30B, RPS30A RPS5 RPS8B, RPS8A RPS9B
View Details	(MIPS) Mewes HW, et al. (2004)		RPL10 RPL11A RPL11B RPL12B, RPL12A RPL13A RPL13B RPL14A RPL14B RPL15A RPL15B RPL16A RPL16B RPL17A RPL17B RPL18A, RPL18B RPL19B, RPL19A RPL1A, RPL1B RPL20A RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL25 RPL26A RPL26B RPL27A RPL27B RPL28 RPL29 RPL2A, RPL2B RPL3 RPL30 RPL31A RPL31B RPL32 RPL33A RPL33B RPL34A RPL34B RPL35A, RPL35B RPL36A RPL36B RPL37A RPL37B RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL4A RPL4B RPL5 RPL6A RPL6B RPL7A RPL7B RPL8A RPL8B RPL9A RPL9B RPP0 RPP1A RPP1B RPP2A RPP2B
View Details	Qiu et al. (2008)		ASC1 ATG27 BUD20 EFT2, EFT1 FYV12 HMS2 MNL1 NAT3 PUF2 RIA1 RKI1 RPL10 RPL11A RPL11B RPL12B, RPL12A RPL13A RPL13B RPL14A RPL14B RPL15A RPL15B RPL16A RPL16B RPL17A RPL17B RPL18A, RPL18B RPL19B, RPL19A RPL1A, RPL1B RPL20A RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL25 RPL26A RPL26B RPL27A RPL27B RPL28 RPL29 RPL2A, RPL2B RPL3 RPL30 RPL31A RPL31B RPL32 RPL33A RPL33B RPL34A RPL34B RPL35A, RPL35B RPL36A RPL36B RPL37A RPL37B RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL4A RPL4B RPL5 RPL6A RPL6B RPL7A RPL7B RPL8A RPL8B RPL9A RPL9B RPP0 RPP1A RPP1B RPP2A RPP2B RPS0A RPS0B RPS10A RPS10B RPS11A, RPS11B RPS12 RPS13 RPS14A RPS14B RPS15 RPS16B, RPS16A RPS17A RPS17B RPS18B, RPS18A RPS19A RPS19B RPS1A RPS1B RPS2 RPS20 RPS21A RPS21B RPS22A RPS22B RPS23B, RPS23A RPS24A, RPS24B RPS25A RPS25B RPS26A RPS26B RPS27A RPS27B RPS28A RPS28B RPS29A RPS29B RPS3 RPS30B, RPS30A RPS31 RPS4B, RPS4A RPS6A, RPS6B RPS7A RPS7B RPS8B, RPS8A RPS9A RPS9B RRP5 SFT1 TEF1, TEF2 TSR1 YDL133W YML6 YPL199C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MIF2	No Comments	Cheeseman IM, et al. (2002)
View Run	TOR2	No Comments	Reinke A, et al. (2004)
View Run	TOR2	No Comments	Reinke A, et al. (2004)
View Run	SEC10	No Comments	De Craene, J., et al. (2006)
View Run	BIR1	No Comments	Widlund PO, et al. (2005)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	DAD1	Dam1-765 complex purified from yeast with Dad1-TAP	Shimogawa MM, et al. (2006)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	RLF2	phosphorylation data - cascade search	Green EM, et al (2005)
View Run	RLF2	identification data - first search in cascade	Green EM, et al (2005)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	BOI1	Sample boi 1 with ha tag from october 2005	McCusker D, et al (2007)
View Run	VAM3	Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control).	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX14 - mixture in detergent (control).	Hao Xu, et al. (2010)
View Run	MLP2	#19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#25 Asynchronous Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#02 Alpha Factor Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#19b Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)
View Run	MLP2	#19a Asynchronous Prep1-new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	RPL21A	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..160]	PSI-BLAST	488.228787	No description for 1k5yQ_ was found.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: RPL21A

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: