From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Sec27. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 29 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
COPI coated vesicle membrane | 1.8006E-10 | 29 | 9 | 5 | 6292 |
COPI vesicle coat | 1.8006E-10 | 29 | 9 | 5 | 6292 |
Golgi-associated vesicle membrane | 6.1043E-9 | 29 | 16 | 5 | 6292 |
COPI-coated vesicle | 2.7988E-8 | 29 | 21 | 5 | 6292 |
vesicle coat | 3.6717E-7 | 29 | 34 | 5 | 6292 |
coated vesicle membrane | 4.27E-7 | 29 | 35 | 5 | 6292 |
cytoplasmic vesicle membrane | 4.27E-7 | 29 | 35 | 5 | 6292 |
vesicle membrane | 4.27E-7 | 29 | 35 | 5 | 6292 |
membrane coat | 6.5394E-7 | 29 | 38 | 5 | 6292 |
coated membrane | 6.5394E-7 | 29 | 38 | 5 | 6292 |
cytoplasmic vesicle part | 7.4772E-7 | 29 | 39 | 5 | 6292 |
Golgi-associated vesicle | 8.5181E-7 | 29 | 40 | 5 | 6292 |
Golgi membrane | 2.3986E-6 | 29 | 49 | 5 | 6292 |
cytoplasmic part | 1.3595E-5 | 29 | 2482 | 23 | 6292 |
cytoplasm | 1.6092E-5 | 29 | 3552 | 27 | 6292 |
coated vesicle | 3.2763E-5 | 29 | 83 | 5 | 6292 |
Golgi apparatus | 1.0425E-4 | 29 | 171 | 6 | 6292 |
membrane-bounded vesicle | 1.111E-4 | 29 | 107 | 5 | 6292 |
cytoplasmic vesicle | 1.111E-4 | 29 | 107 | 5 | 6292 |
cytoplasmic membrane-bounded vesicle | 1.111E-4 | 29 | 107 | 5 | 6292 |
vesicle | 1.2668E-4 | 29 | 110 | 5 | 6292 |
organelle membrane | 1.4106E-4 | 29 | 692 | 11 | 6292 |
Golgi apparatus part | 1.8367E-4 | 29 | 119 | 5 | 6292 |
endomembrane system | 3.1511E-4 | 29 | 398 | 8 | 6292 |
eukaryotic translation initiation factor 3 complex | 4.2467E-4 | 29 | 7 | 2 | 6292 |
membrane part | 4.8333E-4 | 29 | 662 | 10 | 6292 |
mitochondrial outer membrane | 7.6856E-4 | 29 | 92 | 4 | 6292 |
intracellular part | 8.7176E-4 | 29 | 4938 | 29 | 6292 |
intracellular | 1.0831E-3 | 29 | 4975 | 29 | 6292 |
mitochondrial membrane | 1.1266E-3 | 29 | 266 | 6 | 6292 |
membrane | 1.3108E-3 | 29 | 1198 | 13 | 6292 |
envelope | 1.5406E-3 | 29 | 505 | 8 | 6292 |
organelle envelope | 1.5406E-3 | 29 | 505 | 8 | 6292 |
mitochondrial envelope | 2.5537E-3 | 29 | 312 | 6 | 6292 |
protein complex | 2.8676E-3 | 29 | 1137 | 12 | 6292 |
mitochondrial part | 4.8367E-3 | 29 | 475 | 7 | 6292 |
outer membrane | 8.4595E-3 | 29 | 178 | 4 | 6292 |
organelle outer membrane | 8.4595E-3 | 29 | 178 | 4 | 6292 |
eisosome | 9.1975E-3 | 29 | 2 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ER to Golgi vesicle-mediated transport | 1.6363E-6 | 29 | 83 | 6 | 6292 |
Golgi vesicle transport | 9.4494E-5 | 29 | 168 | 6 | 6292 |
vesicle-mediated transport | 1.0561E-4 | 29 | 340 | 8 | 6292 |
retrograde vesicle-mediated transport, Golgi to ER | 2.1318E-4 | 29 | 26 | 3 | 6292 |
lipid biosynthetic process | 2.7684E-3 | 29 | 130 | 4 | 6292 |
phospholipid biosynthetic process | 2.774E-3 | 29 | 62 | 3 | 6292 |
translational readthrough | 4.609E-3 | 29 | 1 | 1 | 6292 |
phosphatidic acid metabolic process | 4.609E-3 | 29 | 1 | 1 | 6292 |
CDP-choline pathway | 4.609E-3 | 29 | 1 | 1 | 6292 |
ADP transport | 4.609E-3 | 29 | 1 | 1 | 6292 |
phosphatidic acid biosynthetic process | 4.609E-3 | 29 | 1 | 1 | 6292 |
aerobic respiration | 6.3163E-3 | 29 | 83 | 3 | 6292 |
glutamine family amino acid biosynthetic process | 7.1991E-3 | 29 | 28 | 2 | 6292 |
anaerobic respiration | 9.1975E-3 | 29 | 2 | 1 | 6292 |
phospholipid metabolic process | 9.4365E-3 | 29 | 96 | 3 | 6292 |
organophosphate metabolic process | 9.7077E-3 | 29 | 97 | 3 | 6292 |
cellular respiration | 9.7077E-3 | 29 | 97 | 3 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
oxidoreductase activity | 2.831E-6 | 29 | 281 | 9 | 6292 |
oxidoreductase activity, acting on CH or CH2 groups | 2.0338E-4 | 29 | 5 | 2 | 6292 |
oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | 4.609E-3 | 29 | 1 | 1 | 6292 |
pyrroline-5-carboxylate reductase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
acylglycerone-phosphate reductase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
malic enzyme activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
choline-phosphate cytidylyltransferase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
argininosuccinate lyase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
3-keto sterol reductase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
deoxyhypusine monooxygenase activity | 4.609E-3 | 29 | 1 | 1 | 6292 |
oxidoreductase activity, acting on CH-OH group of donors | 5.9015E-3 | 29 | 81 | 3 | 6292 |
translation initiation factor activity | 6.7039E-3 | 29 | 27 | 2 | 6292 |
amidine-lyase activity | 9.1975E-3 | 29 | 2 | 1 | 6292 |
glycerol-3-phosphate O-acyltransferase activity | 9.1975E-3 | 29 | 2 | 1 | 6292 |