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Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.

View Gene Ontology (GO) Term


Name: peptidyl-prolyl cis-trans isomerase activity
Acc: GO:0003755
Aspect: Molecular Function
Desc: Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
  • cis-trans proline isomerase activity
  • cyclophilin-type peptidyl-prolyl cis-trans isomerase activity
  • juglone-sensitive cis-trans proline isomerase activity
  • immunophilin
  • peptidylprolyl isomerase activity
  • GO:0042028
  • peptidylproline cis-trans-isomerase activity
  • GO:0004752
  • parvulin
  • cyclophilin activity
  • peptidylprolyl cis-trans isomerase activity
  • peptidyl-prolyl isomerase B reaction
  • peptide bond isomerase activity
  • PPIase activity
  • FK506-sensitive peptidyl-prolyl cis-trans isomerase
  • rotamase activity
  • juglone-sensitive peptidyl-prolyl cis-trans isomerase activity
Proteins in PDR annotated with:
   This term: 320 [Search]
   Term or descendants: 320 [Search]


GO:0003755 - peptidyl-prolyl cis-trans isomerase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle