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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
MIS1
  • mitochondrion
  • ribosome biogenesis
  • folic acid biosynthetic process
  • anaerobic purine catabolic process
  • nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
  • acetate biosynthetic process from carbon monoxide
  • formate-tetrahydrofolate ligase activity
  • methenyltetrahydrofolate cyclohydrolase activity
  • methylenetetrahydrofolate dehydrogenase (NADP+) activity
  • POL1
  • replication fork
  • alpha DNA polymerase:primase complex
  • mitochondrion
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA synthesis involved in DNA repair
  • premeiotic DNA synthesis
  • nucleic acid binding
  • nucleotide binding
  • DNA binding
  • DNA-directed DNA polymerase activity
  • nucleotidyltransferase activity
  • transferase activity
  • nucleoside binding
  • POL12
  • nuclear envelope
  • nucleus
  • alpha DNA polymerase:primase complex
  • DNA replication initiation
  • lagging strand elongation
  • telomere capping
  • DNA binding
  • DNA-directed DNA polymerase activity
  • PRI1
  • alpha DNA polymerase:primase complex
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA replication, synthesis of RNA primer
  • DNA primase activity
  • PRI2
  • nuclear envelope
  • nucleus
  • alpha DNA polymerase:primase complex
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA synthesis involved in DNA repair
  • DNA replication, synthesis of RNA primer
  • DNA primase activity
  • RFC1
  • DNA replication factor C complex
  • DNA repair
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • RFC3
  • nucleus
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • ATPase activity
  • DNA clamp loader activity
  • RFC4
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • purine nucleotide binding
  • RFC5
  • DNA replication factor C complex
  • sister chromatid cohesion
  • leading strand elongation
  • mismatch repair
  • DNA clamp loader activity
  • USO1
  • soluble fraction
  • ER to Golgi vesicle-mediated transport
  • protein complex assembly
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    replication fork 8.6729E-17 10 42 8 6292
    alpha DNA polymerase:primase complex 1.124E-10 10 7 4 6292
    chromosomal part 1.5218E-10 10 237 8 6292
    chromosome 4.8836E-10 10 274 8 6292
    DNA replication factor C complex 1.0565E-9 10 11 4 6292
    nuclear replisome 9.7446E-9 10 18 4 6292
    replisome 9.7446E-9 10 18 4 6292
    nuclear replication fork 1.5405E-8 10 20 4 6292
    protein-DNA complex 1.2209E-6 10 57 4 6292
    non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    intracellular non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    protein complex 3.542E-5 10 1137 8 6292
    nuclear chromosome part 1.467E-4 10 190 4 6292
    nuclear chromosome 2.9689E-4 10 228 4 6292
    macromolecular complex 5.4804E-4 10 1635 8 6292
    organelle part 6.1675E-3 10 2282 8 6292
    intracellular organelle part 6.1675E-3 10 2282 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA strand elongation 5.8148E-18 10 31 8 6292
    DNA strand elongation involved in DNA replication 5.8148E-18 10 31 8 6292
    DNA-dependent DNA replication 2.5892E-14 10 82 8 6292
    DNA replication 7.3943E-13 10 123 8 6292
    leading strand elongation 4.3568E-9 10 15 4 6292
    lagging strand elongation 9.7446E-9 10 18 4 6292
    mismatch repair 5.5505E-8 10 27 4 6292
    DNA replication initiation 1.2882E-7 10 33 4 6292
    DNA repair 1.4173E-7 10 192 6 6292
    DNA metabolic process 2.029E-7 10 585 8 6292
    response to DNA damage stimulus 4.8402E-7 10 236 6 6292
    cellular response to stress 1.6359E-6 10 290 6 6292
    cellular response to stimulus 7.8441E-6 10 379 6 6292
    DNA synthesis involved in DNA repair 1.3619E-5 10 4 2 6292
    sister chromatid cohesion 1.4E-5 10 32 3 6292
    DNA replication, synthesis of RNA primer 2.2679E-5 10 5 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.7984E-5 10 1566 9 6292
    cellular biosynthetic process 2.8141E-5 10 1567 9 6292
    biosynthetic process 3.4126E-5 10 1602 9 6292
    response to stress 3.7616E-5 10 497 6 6292
    cellular macromolecule biosynthetic process 4.9194E-5 10 1187 8 6292
    macromolecule biosynthetic process 4.9829E-5 10 1189 8 6292
    cellular nitrogen compound metabolic process 8.1293E-5 10 1770 9 6292
    nitrogen compound metabolic process 9.0055E-5 10 1791 9 6292
    nucleic acid metabolic process 1.8614E-4 10 1415 8 6292
    response to stimulus 4.3452E-4 10 766 6 6292
    chromosome segregation 8.8893E-4 10 128 3 6292
    pteridine and derivative biosynthetic process 1.5893E-3 10 1 1 6292
    folic acid biosynthetic process 1.5893E-3 10 1 1 6292
    nitrogenous compound catabolic process 1.5893E-3 10 1 1 6292
    anaerobic purine catabolic process 1.5893E-3 10 1 1 6292
    acetate biosynthetic process from carbon monoxide 1.5893E-3 10 1 1 6292
    nucleobase catabolic process 3.1764E-3 10 2 1 6292
    pteridine and derivative metabolic process 3.1764E-3 10 2 1 6292
    purine base catabolic process 3.1764E-3 10 2 1 6292
    folic acid metabolic process 3.1764E-3 10 2 1 6292
    primary metabolic process 5.4001E-3 10 2896 9 6292
    cellular macromolecule metabolic process 6.225E-3 10 2285 8 6292
    acetate biosynthetic process 6.3436E-3 10 4 1 6292
    macromolecule metabolic process 7.5629E-3 10 2349 8 6292
    cellular metabolic process 7.9165E-3 10 3033 9 6292
    telomere capping 7.9239E-3 10 5 1 6292
    premeiotic DNA synthesis 7.9239E-3 10 5 1 6292
    chromosome organization 8.1671E-3 10 555 4 6292
    folic acid and derivative biosynthetic process 9.5019E-3 10 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA clamp loader activity 1.124E-10 10 7 4 6292
    protein-DNA loading ATPase activity 1.124E-10 10 7 4 6292
    DNA binding 7.8367E-7 10 256 6 6292
    DNA-dependent ATPase activity 1.0557E-6 10 55 4 6292
    DNA primase activity 2.2737E-6 10 2 2 6292
    ATPase activity, coupled 5.6775E-5 10 149 4 6292
    nucleotidyltransferase activity 9.0836E-5 10 168 4 6292
    nucleic acid binding 1.9872E-4 10 666 6 6292
    ATPase activity 2.202E-4 10 211 4 6292
    catalytic activity 4.3549E-4 10 2150 9 6292
    nucleoside-triphosphatase activity 1.1988E-3 10 329 4 6292
    RNA polymerase activity 1.2414E-3 10 34 2 6292
    DNA-directed RNA polymerase activity 1.2414E-3 10 34 2 6292
    hydrolase activity, acting on acid anhydrides 1.5609E-3 10 353 4 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.5609E-3 10 353 4 6292
    pyrophosphatase activity 1.5609E-3 10 353 4 6292
    transferase activity, transferring phosphorus-containing groups 2.9742E-3 10 420 4 6292
    methylenetetrahydrofolate dehydrogenase (NADP+) activity 3.1764E-3 10 2 1 6292
    methenyltetrahydrofolate cyclohydrolase activity 3.1764E-3 10 2 1 6292
    formate-tetrahydrofolate ligase activity 3.1764E-3 10 2 1 6292
    nucleotide binding 3.7066E-3 10 59 2 6292
    methylenetetrahydrofolate dehydrogenase activity 4.7611E-3 10 3 1 6292
    binding 7.3119E-3 10 1294 6 6292
    hydrolase activity 8.4227E-3 10 911 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle