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A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins. A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. A macromolecular complex containing both protein and DNA molecules. A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: replisome
Acc: GO:0030894
Aspect: Cellular Component
Desc: A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
Synonyms:
  • DNA synthesome complex
  • replication-competent complex
  • RC complex
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 127 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030894 - replisome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle