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Protein Overview: EAF7

General Information:
Name(s) found: EAF7 / YNL136W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 425 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    NuA4 histone acetyltransferase complex [IPILink to PubMed article]
    histone acetyltransferase complex [IDALink to PubMed article]
    Biological Process: DNA repair [IDALink to PubMed article][IPILink to PubMed article]
    histone acetylation [IPILink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVHWTIVDE IRLLRWASEF KPAGIHKHFH MFCIVERMNS PDKYPVTLLQ KETMKLGKVF  60
   61 TAKDIWDKLS QSYNLEKIDE MENTYSLEAT TESSRNGNGN GDDAEIHEET LLELNNRIRV 120
  121 RKQDFTLPWE EYGELILENA RKSPNSNEEY PRVEDMNEKD STIPKESPST DLKNDNNKQE 180
  181 KNATIKVKEL PEYHTEENDS PIDVQKEPIK EVQSDEKELQ REHMSEEEQK MKSTNKTAAP 240
  241 VRKSQRLKRS KEVKFEDEEK EEIEEDNTKD EEQKEKKEEI QEPKITHNEE VDKEKNENEE 300
  301 GDDEREKSTS YENTNGSESE GVDEGVDEEL GYESEREAEG KGKQIESEGG NLKKKTENKK 360
  361 GDDQQDDTKK DSKDKNEPLA KRTRHSSSTG NTSNETSPKR KRRKAGSRKN SPPATRVSSR 420
  421 LRNKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP4 EAF1 EAF3 EAF5 EAF6 EAF7 EPL1 ESA1 SRP1 SWC4 YAF9 YNG2
    View Details Krogan NJ, et al. (2006) ARP4 ARP5 ARP6 ARP8 CCA1 EAF1 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES4 IES5 IES6 INO80 NHP10 NTO1 PIH1 RVB1 RVB2 SAS3 SWC3 SWC4 SWC5 SWC7 SWR1 TAH1 TRA1 VPS71 VPS72 YAF9 YNG2
    View Details Qiu et al. (2008) ARP4 EAF7 TRA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SWC4 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data EAF7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] deduced N/A No confident structure predictions are available.
    2 View Details [122..425] ab initio 14.63 No description for 1ldvA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle