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Protein Overview: IES2

General Information:
Name(s) found: IES2 / YNL215W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; essential for growth under anaerobic conditions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 320 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSEASDIEA ELSDSVSAGG EEYIDDDDYT EDIDDQIVTA KSSRRTARRS VPKGVRTSKR  60
   61 IRDKELSVEV DEDYDEEEDV LSPSKKRHLH TRSMDKRQVA ATASEKSDIG DSKGNDGEIE 120
  121 DGILEEEESL EKELNRGGGK EVEKSEESYY AQNDVGQKGE EEQDGESGGY EDNEPSISKE 180
  181 SDELVSVVNG NGNEEDDEVE ATKENTTDST RSTTTRSKML LDLLEDGGSK KKLTDEEIQL 240
  241 RRAENARKRK NLSEKRLEEE KQDTINKLLK KRAGKSRSHL PNDDEKNDGS SSFVKPRRPY 300
  301 NSEGMTRILR RYEEDLFCTF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP4 ARP8 IES1 IES2 IES3 IES5 NHP10 RVB1 RVB2
    View Details Krogan NJ, et al. (2006) ARP4 ARP5 ARP6 ARP8 CCA1 EAF1 EAF5 EAF6 EAF7 EPL1 ESA1 IES1 IES2 IES3 IES4 IES5 IES6 INO80 NHP10 NTO1 PIH1 RVB1 RVB2 SAS3 SWC3 SWC4 SWC5 SWC7 SWR1 TAH1 TRA1 VPS71 VPS72 YAF9 YNG2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data IES2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..22]
    [250..320]    		 ORFEUS 10.82 No description for 1l8mA was found.
    2 View Details [23..95] ORFEUS 10.82 No description for 1l8mA was found.
    3 View Details [96..175] ORFEUS 10.82 No description for 1l8mA was found.
    4 View Details [176..249] ORFEUS 10.82 No description for 1l8mA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle