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Protein Overview: UTP14

General Information:
Name(s) found: UTP14 / YML093W [SGD]
Description(s) found:
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  • gi|6323546|ref|NP_013617.1| Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; Utp14p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|575710|emb|CAA86645.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2497072|sp|Q04500.1|UTP14_YEAST RecName: Full=U3 small nucleolar RNA-associated protein 14; Short=U3 snoRNA-associated protein 14; AltName: Full=U three protein 14 [NCBI NR]
  • pir||S49634 hypothetical protein YML093w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • (Q04500) Hypothetical 103.0 kDa protein in RAD10-PRS4 intergenic region [Swiss-Prot]
  • U3 small nucleolar RNA-associated protein 14 OS=Saccharomyces cerevisiae GN=UTP14 PE=1 SV=1 [Swiss-Prot]
  • UTP14 Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [mips]
  • Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit [SGD]
  • YML093W, Chr XIII from 83090-85789 [yeast_orfs2]
  • Chr XIII from 83090-85789 [yeastorf3.fasta]
  • UTP14 SGDID:S0004558, Chr XIII from 83090-85789, Verified ORF [yeastflysequest.fasta]
  • Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA [Saccharomyces cerevisiae]gi|575710|emb|CAA86645.1| unnamed protein product [Saccharomyces cerevisiae]gi|2497072|s [nrdb_11152004_Chlamydomonas]
  • UTP14 SGDID:S000004558, Chr XIII from 83090-85789, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • UTP14 SGDID:S000004558, Chr XIII from 83090-85789, Verified ORF, "Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit" [yeast-200209-contam.fasta]
  • U3 small nucleolar RNA-associated protein 14 (U3 snoRNA-associated protein 14) [nr-271106-contam.fasta]
  • Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; Utp14p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • U3 small nucleolar RNA-associated protein 14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UTP14 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • UTP14 SGDID:S000004558, Chr XIII from 83090-85789, Genome Release 64-1-1, Verified ORF, "Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit" [yeast-030211-contam.fasta]
  • UTP14 SGDID:S000004558, Chr XIII from 83090-85789, Genome Release 64-2-1, Verified ORF, "Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit" [20141208_orf_trans.fasta]
  • YML093W SGDID:S000004558, Chr XIII from 83090-85789, Genome Release 64-1-1, Verified ORF, "Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 899 amino acids

    Gene Ontology:
    Cellular Component: small nucleolar ribonucleoprotein complex [IPILink to PubMed article]
    Biological Process: maturation of SSU-rRNA [IMPLink to PubMed article][IPILink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: snoRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKKSKSRS KSSRRVLDAL QLAEREINGE FDNSSDNDKR HDARRNGTVV NLLKRSKGDT  60
   61 NSDEDDIDSE SFEDEELNSD EALGSDDDYD ILNSKFSQTI RDKKENANYQ EEEDEGGYTS 120
  121 IDEEDLMPLS QVWDMDEKTA QSNGNDDEDA SPQLKLQDTD ISSESSSSEE SESESEDDEE 180
  181 EEDPFDEISE DEEDIELNTI TSKLIDETKS KAPKRLDTYG SGEANEYVLP SANAASGASG 240
  241 KLSLTDMMNV IDDRQVIENA NLLKGKSSTY EVPLPQRIQQ RHDRKAAYEI SRQEVSKWND 300
  301 IVQQNRRADH LIFPLNKPTE HNHASAFTRT QDVPQTELQE KVDQVLQESN LANPEKDSKF 360
  361 EELSTAKMTP EEMRKRTTEM RLMRELMFRE ERKARRLKKI KSKTYRKIKK KELMKNRELA 420
  421 AVSSDEDNED HDIARAKERM TLKHKTNSKW AKDMIKHGMT NDAETREEME EMLRQGERLK 480
  481 AKMLDRNSDD EEDGRVQTLS DVENEEKENI DSEALKSKLG KTGVMNMAFM KNGEAREREA 540
  541 NKETLRQLRA VENGDDIKLF ESDEEETNGE NIQINKGRRI YTPGSLESNK DMNELNDHTR 600
  601 KENKVDESRS LENRLRAKNS GQSKNARTNA EGAIIVEEES DGEPLQDGQN NQQDEEAKDV 660
  661 NPWLANESDE EHTVKKQSSK VNVIDKDSSK NVKAMNKMEK AELKQKKKKK GKSNDDEDLL 720
  721 LTADDSTRLK IVDPYGGSDD EQGDNVFMFK QQDVIAEAFA GDDVVAEFQE EKKRVIDDED 780
  781 DKEVDTTLPG WGEWAGAGSK PKNKKRKFIK KVKGVVNKDK RRDKNLQNVI INEKVNKKNL 840
  841 KYQSSAVPFP FENREQYERS LRMPIGQEWT SRASHQELIK PRIMTKPGQV IDPLKAPFK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GCN1 GCN20 RSA4 UTP14 YHL039W
    View Details Ho Y, et al. (2002) CKA1 CKA2 CKB1 CKB2 DIP2 ESL2 KRE33 LCP5 NAN1 NOP1 NOP56 PNO1 PRP40 PTC5 PWP2 RRP5 TFP1 UTP10 UTP11 UTP13 UTP14 UTP18 UTP21 UTP22 UTP30 UTP6
    View Details Qiu et al. (2008) BUD21 DIP2 DRS1 ENP1 GAR1 LCP5 NAN1 NHP2 PWP2 PXR1 RRP5 RRP9 SOF1 UTP11 UTP13 UTP14 UTP15 UTP4 UTP5 UTP6 UTP7 UTP8 UTP9

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TAM41 No Comments Hazbun TR, et al. (2003)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data UTP14 and NOP56 Huh WK, et al. (2003)
    View Data UTP14 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..320] PSI-BLAST 6.522879 Heavy meromyosin subfragment
    2 View Details [321..816] MSA 14.287996 View MSA. No confident structure predictions are available.
    3 View Details [817..899] deduced N/A No confident structure predictions are available.
    4 View Details [643..762] deduced N/A No confident structure predictions are available.
    5 View Details [763..899] MSA 1.157982 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle