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Protein Overview: YAR009C

General Information:
Name(s) found: YAR009C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Retrotransposon TYA Gag and TYB Pol genes; in YARCTY1-1 TYB is mutant and probably non-functional [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1196 amino acids

    Gene Ontology:
    Cellular Component: retrotransposon nucleocapsid [ISSLink to PubMed article]
    Biological Process: transposition, RNA-mediated [ISSLink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [ISSLink to PubMed article]
    RNA-directed DNA polymerase activity [ISSLink to PubMed article]
    RNA binding [ISSLink to PubMed article]
    protein binding [ISSLink to PubMed article]
    ribonuclease activity [ISSLink to PubMed article]
    peptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METFTGYLKS TCFHQISPYP PSIMSIQVKV HANILILSFI ECLRMPMHRQ IRYSLKNNTI  60
   61 TYFNESDVDW SSAIDYQCPD CLIGKSTKHR HIKGSRLKYQ NSYEPFQYLH TDIFGPVHNL 120
  121 PKSAPSYFIS FTDETTKLRW VYPLHDRRED SILDVFTTIL AFIKNQFQAS VLVIQMDRGS 180
  181 EYTNRTLHKF LEKNGITPCY TTTADSRAHG VAERLNRTLL DDCRTQLQCS GLPNHLWFSA 240
  241 IEFSTIVRNS LASPKSKKSA RQHAGLAGLD ISTLLPFGQP VIVNDHNPNS KIHPRGIPGY 300
  301 ALHPSRNSYG YIIYLPSLKK TVDTTNYVIL QGKESRLDQF NYDALTFDED LNRLTASYHS 360
  361 FIASNEIQES NDLNIESDHD FQSDIELHPE QPRNVLSKAV SPTDSTPPST HTEDSKRVSK 420
  421 TNIRAPREVD PNISESNILP SKKRSSTPQI SNIESTGSGG MHKLNVPLLA PMSQSNTHES 480
  481 SHASKSKDFR HSDSYSENET NHTNVPISST GGTNNKTVPQ ISDQETEKRI IHRSPSIDAS 540
  541 PPENNSSHNI VPIKTPTTVS EQNTEESIIA DLPLPDLPPE SPTEFPDPFK ELPPINSHQT 600
  601 NSSLGGIGDS NAYTTINSKK RSLEDNETEI KVSRDTWNTK NMRSLEPPRS KKRIHLIAAV 660
  661 KAVKSIKPIR TTLRYDEAIT YNKDIKEKEK YIEAYHKEVN QLLKMNTWDT DKYYDRKEID 720
  721 PKRVINSMFI FNKKRDGTHK ARFVARGDIQ HPDTYDTGMQ SNTVHHYALM TSLSLALDNN 780
  781 YYITQLDISS AYLYADIKEE LYIRPPPHLG MNDKLIRLKK SLYGLKQSGA NWYETIKSYL 840
  841 IKQCGMEEVR GWSCVFKNSQ VTICLFVDDM ILFSKDLNAN KKIITTLKKQ YDTKIINLGE 900
  901 SDNEIQYDIL GLEIKYQRGK YMKLGMEKSL TEKLPKLNVP LNPKGKKLRA PGQPGLYIDQ 960
  961 DELEIDEDEY KEKVHEMQKL IGLASYVGYK FRFDLLYYIN TLAQHILFPS RQVLDMTYEL1020
 1021 IQFMWDTRDK QLIWHKNKPT EPDNKLVAIS DASYGNQPYY KSQIGNIYLL NGKVIGGKST1080
 1081 KASLTCTSTT EAEIHAISES VPLLNNLSYL IQELNKKPII KGLLTDSRST ISIIKSTNEE1140
 1141 KFRNRFFGTK AMRLRDEVSG NNLYVYYIET KKNIADVMTK PLPIKTFKLL TNKWIH

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADR1 BBC1 CDC39 CDC53 CRM1 DUR1,2 ECM29 ECM33 FAA4 GAL3 GCN1 HRT1 HYP2 MDN1 MKT1 MMS1 MYO2 PFK1 PMA2 RPA190 RPN1 TPS1 UBI4 VPS13 YAR009C YGP1 YLR035C-A
    View Details Qiu et al. (2008) YAR009C YBR012W-B YDR210C-C YDR210C-D YGR027W-B YHR214C-B YJL113W YJR027W YJR029W YML045W YOR142W-B YOR343W-A YOR343W-B

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run YNL313C No Comments Hazbun TR, et al. (2003)
    View Run YMR185W No Comments Hazbun TR, et al. (2003)
    View Run MIA40 No Comments Hazbun TR, et al. (2003)
    View Run LST8 No Comments Reinke A, et al. (2004)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RLF2 cac1: TAP-tagged Green EM, et al (2005)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run MLP2 #04 Alpha Factor Prep2 Keck JM, et al. (2011)
    View Run MLP2 #06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YAR009C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..342] PSI-BLAST 35.69897 N-terminal Zn binding domain of HIV integrase; Retroviral integrase, catalytic domain
    2 View Details [343..519] FFAS03 1.5 DNA-binding domain of retroviral integrase; Retroviral integrase, catalytic domain
    3 View Details [520..590] deduced N/A No confident structure predictions are available.
    4 View Details [591..1196] FFAS03 1.59 HIV RNase H (Domain of reverse transcriptase); HIV-1 reverse transcriptase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  1.94987701094917 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.969438660919194 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.787213833707638 bayes_pls_golite062009
  • exonuclease activity
    		•  0.738049151007118 bayes_pls_golite062009
  • catalytic activity
    		•  0.709734459150736 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.332143782945747 bayes_pls_golite062009
  • hydrolase activity
    		•  0.301910249637397 bayes_pls_golite062009
  • binding
    		•  0.205040227344888 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nuclease activity
    		•  1.46638847734081 bayes_pls_golite062009
  • catalytic activity
    		•  0.626203923982956 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.519152306822884 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.433654553131226 bayes_pls_golite062009
  • exonuclease activity
    		•  0.292985426209423 bayes_pls_golite062009
  • binding
    		•  0.27027344947123 bayes_pls_golite062009
  • hydrolase activity
    		•  0.104087157972011 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • nucleotidyltransferase activity
    		•  1.61389461562101 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.895925817051023 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.71944542861368 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.710149896697621 bayes_pls_golite062009
  • binding
    		•  0.698775322116598 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.519152306822884 bayes_pls_golite062009
  • catalytic activity
    		•  0.443190761359386 bayes_pls_golite062009
  • transferase activity
    		•  0.343279650271418 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0241260721327641 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle