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Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer. Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Catalysis of the transfer of a nucleotidyl group to a reactant.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: RNA-directed DNA polymerase activity
Acc: GO:0003964
Aspect: Molecular Function
Desc: Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
Synonyms:
  • RNA-directed DNA polymerase, transposon encoded
  • RT
  • RNA-dependent deoxyribonucleate nucleotidyltransferase activity
  • RNA-instructed DNA polymerase activity
  • RNA revertase activity
  • deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity
  • RNA-dependent DNA polymerase activity
  • RNA-directed DNA polymerase, group II intron encoded
  • reverse transcriptase activity
  • revertase activity
  • DNA nucleotidyltransferase (RNA-directed) activity
Proteins in PDR annotated with:
   This term: 227 [Search]
   Term or descendants: 239 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003964 - RNA-directed DNA polymerase activity (interactive image map)

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