YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Gavin A.C. et al. (2002) Abstract Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 2002 Jan 10;415(6868):141-7.
Notes:	From the published set of protein complexes.
Complex Size:	40 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
BEM2	mitochondrion intracellular	small GTPase mediated signal transduction cellular cell wall organization microtubule cytoskeleton organization budding cell bud growth actin cytoskeleton organization	Rho GTPase activator activity signal transducer activity
CCM1	mitochondrion	biological_process	molecular_function
ECM16	mitochondrion nucleolus small nucleolar ribonucleoprotein complex	maturation of SSU-rRNA ribosome biogenesis	RNA helicase activity
EHD3	mitochondrion	fatty acid beta-oxidation endocytosis	3-hydroxyisobutyryl-CoA hydrolase activity
FYV4	mitochondrion	telomere maintenance	molecular_function
GEP3	mitochondrion	biological_process	molecular_function
HSC82	cytoplasm mitochondrion	telomere maintenance protein folding protein refolding proteasome assembly 'de novo' protein folding response to stress	unfolded protein binding ATPase activity, coupled
MRP1	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRP10	mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRP13	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRP17	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRP21	mitochondrion mitochondrial small ribosomal subunit	translational initiation translation	structural constituent of ribosome
MRP4	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome tRNA binding
MRP51	mitochondrion mitochondrial small ribosomal subunit	translational initiation translation	structural constituent of ribosome
MRPS16	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRPS17	mitochondrion mitochondrial small ribosomal subunit	aerobic respiration translation	structural constituent of ribosome
MRPS18	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRPS28	mitochondrion mitochondrial small ribosomal subunit	ribosomal small subunit assembly translation	RNA binding structural constituent of ribosome
MRPS5	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRPS8	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
MRPS9	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
NAM9	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
PAP2	nucleus TRAMP complex	mitotic chromosome condensation ncRNA polyadenylation mitotic sister chromatid cohesion rRNA catabolic process snRNA catabolic process snoRNA catabolic process tRNA catabolic process DNA topological change ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process polyadenylation-dependent ncRNA catabolic process	DNA-directed DNA polymerase activity polynucleotide adenylyltransferase activity
PET123	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
PSD2	fungal-type vacuole membrane Golgi membrane	phosphatidylcholine biosynthetic process	phosphatidylserine decarboxylase activity
PUS7	nucleus	pseudouridine synthesis snRNA modification ribosome biogenesis tRNA modification	pseudouridine synthase activity
RIX1	nucleus nuclear outer membrane nucleoplasm	ribosomal subunit export from nucleus ribosome biogenesis ribosomal large subunit assembly	molecular_function
RSM10	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM19	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM22	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM23	mitochondrion mitochondrial small ribosomal subunit	response to drug translation	structural constituent of ribosome
RSM24	mitochondrion mitochondrial small ribosomal subunit	aerobic respiration translation	structural constituent of ribosome
RSM25	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM26	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM27	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
RSM7	mitochondrion mitochondrial small ribosomal subunit	translation	structural constituent of ribosome
TIF4631	eukaryotic translation initiation factor 4F complex mitochondrion ribosome	ribosome biogenesis translational initiation	translation initiation factor activity
UBP10	nucleus	protein deubiquitination chromatin silencing at telomere	ubiquitin-specific protease activity
UTP20	cytoplasm nuclear outer membrane nucleolus small nucleolar ribonucleoprotein complex	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing	snoRNA binding
UTP22	nucleus nuclear outer membrane nucleolus small nucleolar ribonucleoprotein complex	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis rRNA processing	snoRNA binding

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
mitochondrial small ribosomal subunit	1.2588E-51	40	35	25	6292
organellar small ribosomal subunit	1.2588E-51	40	35	25	6292
small ribosomal subunit	1.4579E-40	40	73	25	6292
mitochondrial ribosome	7.0107E-38	40	90	25	6292
organellar ribosome	7.0107E-38	40	90	25	6292
mitochondrial matrix	7.2991E-30	40	176	25	6292
mitochondrial lumen	7.2991E-30	40	176	25	6292
ribosomal subunit	2.0453E-29	40	183	25	6292
ribosome	7.7322E-26	40	290	26	6292
ribonucleoprotein complex	1.3295E-23	40	514	29	6292
organelle lumen	1.711E-20	40	660	29	6292
intracellular organelle lumen	1.711E-20	40	660	29	6292
membrane-enclosed lumen	9.0625E-20	40	700	29	6292
mitochondrial part	6.7225E-19	40	475	25	6292
mitochondrion	7.3323E-19	40	1125	33	6292
non-membrane-bounded organelle	5.9443E-16	40	959	29	6292
intracellular non-membrane-bounded organelle	5.9443E-16	40	959	29	6292
macromolecular complex	1.1149E-10	40	1635	30	6292
membrane-bounded organelle	1.1763E-9	40	3771	40	6292
intracellular membrane-bounded organelle	1.1763E-9	40	3771	40	6292
cytoplasmic part	3.5042E-9	40	2482	34	6292
intracellular organelle	2.5274E-8	40	4070	40	6292
organelle	2.5525E-8	40	4071	40	6292
intracellular organelle part	1.1359E-7	40	2282	31	6292
organelle part	1.1359E-7	40	2282	31	6292
cytoplasm	2.4139E-5	40	3552	35	6292
intracellular part	5.9657E-5	40	4938	40	6292
intracellular	8.0511E-5	40	4975	40	6292
cell part	2.1163E-3	40	5397	40	6292
cell	2.148E-3	40	5399	40	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation	7.1442E-23	40	376	26	6292
gene expression	8.0315E-16	40	1283	32	6292
cellular protein metabolic process	1.6046E-13	40	1074	28	6292
protein metabolic process	6.8665E-13	40	1136	28	6292
cellular macromolecule biosynthetic process	2.0359E-11	40	1187	27	6292
macromolecule biosynthetic process	2.1214E-11	40	1189	27	6292
cellular macromolecule metabolic process	2.754E-10	40	2285	34	6292
macromolecule metabolic process	6.4686E-10	40	2349	34	6292
cellular biosynthetic process	2.2633E-9	40	1567	28	6292
biosynthetic process	3.8804E-9	40	1602	28	6292
primary metabolic process	5.7105E-9	40	2896	36	6292
cellular metabolic process	2.6053E-8	40	3033	36	6292
metabolic process	9.599E-8	40	3157	36	6292
cellular process	1.1683E-4	40	4426	38	6292
snRNA metabolic process	1.3793E-3	40	9	2	6292
translational initiation	2.3016E-3	40	42	3	6292
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.9408E-3	40	13	2	6292
ribosome biogenesis	5.5313E-3	40	346	7	6292
maturation of SSU-rRNA	6.0496E-3	40	59	3	6292
snRNA modification	6.3573E-3	40	1	1	6292
ribonucleoprotein complex biogenesis	8.4019E-3	40	374	7	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
structural constituent of ribosome	9.6475E-28	40	212	25	6292
structural molecule activity	1.5658E-22	40	339	25	6292
3-hydroxyisobutyryl-CoA hydrolase activity	6.3573E-3	40	1	1	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis