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The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically. The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule. The addition a sulfur atom to a nucleotide in a tRNA molecule. The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine. The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. The process whereby the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. The chemical reactions and pathways resulting in the formation of threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: tRNA modification
Acc: GO:0006400
Aspect: Biological Process
Desc: The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
Synonyms:
  • GO:0016549
  • tRNA editing
Proteins in PDR annotated with:
   This term: 256 [Search]
   Term or descendants: 409 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006400 - tRNA modification (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle