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Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. Catalysis of the transfer of a functional group from one position to another within a single molecule. Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: pseudouridine synthase activity
Acc: GO:0009982
Aspect: Molecular Function
Desc: Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
Synonyms:
  • GO:0016439
  • transfer RNA pseudouridine synthetase activity
  • tRNA-pseudouridine synthase activity
  • tRNA-pseudouridine synthase I activity
  • transfer ribonucleate pseudouridine synthetase activity
  • tRNA-uridine uracilmutase activity
  • tRNA-uridine isomerase activity
  • tRNA pseudouridylate synthase I activity
Proteins in PDR annotated with:
   This term: 156 [Search]
   Term or descendants: 156 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0009982 - pseudouridine synthase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle