YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 510.100
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CCL1
  • mitochondrion
  • holo TFIIH complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • transcription initiation from RNA polymerase II promoter
  • cyclin-dependent protein kinase regulator activity
  • general RNA polymerase II transcription factor activity
  • KIN28
  • holo TFIIH complex
  • protein amino acid phosphorylation
  • positive regulation of transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter
  • cyclin-dependent protein kinase activating kinase activity
  • RNA polymerase II carboxy-terminal domain kinase activity
  • general RNA polymerase II transcription factor activity
  • cyclin-dependent protein kinase activity
  • RAD3
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • DNA helicase activity
  • general RNA polymerase II transcription factor activity
  • SSL1
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • SSL2
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter
  • DNA helicase activity
  • general RNA polymerase II transcription factor activity
  • TFB1
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TFB2
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TFB3
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TFB4
  • holo TFIIH complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    holo TFIIH complex 2.3613E-28 9 10 9 6292
    DNA-directed RNA polymerase II, holoenzyme 1.7889E-19 9 56 9 6292
    transcription factor complex 1.7585E-18 9 71 9 6292
    nucleotide-excision repair factor 3 complex 6.8365E-18 9 7 6 6292
    nucleotide-excision repair complex 5.2694E-14 9 21 6 6292
    nucleoplasm part 1.7837E-13 9 245 9 6292
    nucleoplasm 3.5315E-13 9 264 9 6292
    nuclear lumen 4.8255E-11 9 453 9 6292
    organelle lumen 1.4638E-9 9 660 9 6292
    intracellular organelle lumen 1.4638E-9 9 660 9 6292
    membrane-enclosed lumen 2.4937E-9 9 700 9 6292
    nuclear part 1.5218E-7 9 1103 9 6292
    protein complex 2.0019E-7 9 1137 9 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    nucleus 3.9292E-5 9 2041 9 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    negative regulation of transcription from RNA polymerase II promoter, mitotic 1.4838E-25 9 8 8 6292
    regulation of transcription from RNA polymerase II promoter, mitotic 1.4838E-25 9 8 8 6292
    regulation of transcription, mitotic 1.3353E-24 9 9 8 6292
    negative regulation of transcription, mitotic 1.3353E-24 9 9 8 6292
    transcription initiation from RNA polymerase II promoter 3.2176E-20 9 47 9 6292
    transcription initiation 2.5145E-19 9 58 9 6292
    nucleotide-excision repair, DNA duplex unwinding 9.7705E-19 9 6 6 6292
    negative regulation of transcription from RNA polymerase II promoter 3.7687E-16 9 60 8 6292
    protein complex biogenesis 2.6522E-15 9 155 9 6292
    protein complex assembly 2.6522E-15 9 155 9 6292
    DNA geometric change 3.7654E-14 9 20 6 6292
    DNA duplex unwinding 3.7654E-14 9 20 6 6292
    regulation of transcription from RNA polymerase II promoter 9.2334E-14 9 228 9 6292
    macromolecular complex assembly 6.245E-13 9 281 9 6292
    negative regulation of transcription, DNA-dependent 1.1094E-12 9 157 8 6292
    negative regulation of RNA metabolic process 1.1684E-12 9 158 8 6292
    negative regulation of transcription 1.5835E-12 9 164 8 6292
    negative regulation of gene expression 1.5835E-12 9 164 8 6292
    nucleotide-excision repair 2.6622E-12 9 38 6 6292
    negative regulation of macromolecule biosynthetic process 2.6871E-12 9 175 8 6292
    transcription from RNA polymerase II promoter 3.1026E-12 9 335 9 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.3794E-12 9 180 8 6292
    negative regulation of nitrogen compound metabolic process 3.3794E-12 9 180 8 6292
    negative regulation of biosynthetic process 5.0244E-12 9 189 8 6292
    negative regulation of cellular biosynthetic process 5.0244E-12 9 189 8 6292
    macromolecular complex subunit organization 5.5368E-12 9 357 9 6292
    regulation of transcription, DNA-dependent 5.6795E-12 9 358 9 6292
    negative regulation of macromolecule metabolic process 5.7101E-12 9 192 8 6292
    regulation of RNA metabolic process 6.4437E-12 9 363 9 6292
    regulation of transcription 1.0749E-11 9 384 9 6292
    cellular component assembly 1.1006E-11 9 385 9 6292
    negative regulation of cellular metabolic process 1.1366E-11 9 209 8 6292
    negative regulation of metabolic process 1.1815E-11 9 210 8 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.1771E-11 9 415 9 6292
    regulation of nitrogen compound metabolic process 2.2253E-11 9 416 9 6292
    DNA conformation change 3.8711E-11 9 58 6 6292
    regulation of gene expression 4.1046E-11 9 445 9 6292
    negative regulation of cellular process 4.8431E-11 9 250 8 6292
    regulation of macromolecule biosynthetic process 5.1235E-11 9 456 9 6292
    negative regulation of biological process 5.3329E-11 9 253 8 6292
    regulation of cellular biosynthetic process 7.0071E-11 9 472 9 6292
    regulation of biosynthetic process 7.1431E-11 9 473 9 6292
    regulation of macromolecule metabolic process 9.4829E-11 9 488 9 6292
    transcription, DNA-dependent 1.2481E-10 9 503 9 6292
    RNA biosynthetic process 1.3652E-10 9 508 9 6292
    regulation of primary metabolic process 1.5187E-10 9 514 9 6292
    regulation of cellular metabolic process 2.221E-10 9 536 9 6292
    regulation of metabolic process 2.6702E-10 9 547 9 6292
    transcription 2.8998E-10 9 552 9 6292
    cellular component biogenesis 2.3068E-9 9 694 9 6292
    regulation of cellular process 7.978E-9 9 796 9 6292
    regulation of biological process 1.0907E-8 9 824 9 6292
    RNA metabolic process 4.101E-8 9 954 9 6292
    DNA repair 5.8167E-8 9 192 6 6292
    response to DNA damage stimulus 1.9987E-7 9 236 6 6292
    cellular macromolecule biosynthetic process 2.9528E-7 9 1187 9 6292
    macromolecule biosynthetic process 2.9981E-7 9 1189 9 6292
    biological regulation 3.591E-7 9 1213 9 6292
    gene expression 5.9596E-7 9 1283 9 6292
    cellular response to stress 6.8068E-7 9 290 6 6292
    nucleic acid metabolic process 1.4425E-6 9 1415 9 6292
    cellular response to stimulus 3.3052E-6 9 379 6 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6017E-6 9 1566 9 6292
    cellular biosynthetic process 3.6225E-6 9 1567 9 6292
    cellular component organization 3.9477E-6 9 1582 9 6292
    biosynthetic process 4.4215E-6 9 1602 9 6292
    cellular nitrogen compound metabolic process 1.0872E-5 9 1770 9 6292
    nitrogen compound metabolic process 1.2092E-5 9 1791 9 6292
    response to stress 1.6121E-5 9 497 6 6292
    DNA metabolic process 4.1436E-5 9 585 6 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    response to stimulus 1.9375E-4 9 766 6 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    metabolic process 2.004E-3 9 3157 9 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    general RNA polymerase II transcription factor activity 6.5031E-19 9 64 9 6292
    RNA polymerase II transcription factor activity 5.1988E-16 9 130 9 6292
    transcription regulator activity 3.4568E-12 9 339 9 6292
    DNA helicase activity 9.9648E-4 9 34 2 6292
    RNA polymerase II carboxy-terminal domain kinase activity 1.4304E-3 9 1 1 6292
    protein kinase regulator activity 1.8221E-3 9 46 2 6292
    kinase regulator activity 2.0657E-3 9 49 2 6292
    cyclin-dependent protein kinase activating kinase activity 2.859E-3 9 2 1 6292
    helicase activity 5.8284E-3 9 83 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle