YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: TFB2

General Information:
Name(s) found: TFB2 / YPL122C [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 513 amino acids

    Gene Ontology:
    Cellular Component: holo TFIIH complex [IDALink to PubMed articleLink to PubMed article]
    nucleotide-excision repair factor 3 complex [TASLink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter, mitotic [TASLink to PubMed article]
    nucleotide-excision repair, DNA duplex unwinding [TASLink to PubMed article]
    nucleotide-excision repair [TASLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [TASLink to PubMed articleLink to PubMed article]
    Molecular Function: general RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDYSLKHSV TQYLEEIPQQ VQNRLYTSPA TCLAIYRILP PLAKFFIMAM VFNENEVPLL  60
   61 DLDKWVNSNG KLQFQNAIKS MKSLHLLIPN KSSGTLMINL NPTFKISLRN ALTGGEVQNS 120
  121 FGVVVEENVV SLDLLDEYSA NKWETILHFM VGTPLAKIPS EKVLNLLKHS KLMEEVNSTG 180
  181 EFKITNEGFQ FLLQEINSQL WTLLLQYLKM IETSKMDLVD VLHFIFMLGA LEVGKAYKID 240
  241 ALSETQRIML QDMRDYGLVF QKHSNDSIFY PTKLALMLTS DTKTIRSASN AMDSVLRQNR 300
  301 EEPSVNEDGA NGKSTTDITT SDDLNKAGLK NQDIPDGSLI VETNFKIYSY SNSPLQIAVL 360
  361 SLFVHLKARF VNMVLGQITR ESIRRALTNG ITADQIIAYL ETHAHPQMRR LAEEKLEKKL 420
  421 ELDPNCKEPL QVLPPTVVDQ IRLWQLELDR VITYEGSLYS DFETSQEYNL LSKYAQDIGV 480
  481 LLWKDDKKKK FFISKEGNSQ VLDFAKRKLK KKQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) CCL1 KIN28 RAD2 RAD3 SSL1 SSL2 TFB1 TFB2 TFB3 TFB4
    View Details Krogan NJ, et al. (2006) TFB2 TFB5
    View Details Qiu et al. (2008) ABF1 CCL1 KIN28 RAD3 SSL1 SSL2 TFA1 TFB1 TFB2 TFB3 TFB4 TFB5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TFB2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] Pfam 291.136677 Transcription factor Tfb2 No confident structure predictions are available.
    2 View Details [415..513] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle