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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromatin silencing complex 2.0243E-9 3 9 3 6292
RENT complex 9.0929E-7 3 4 2 6292
nuclear telomeric heterochromatin 3.1815E-6 3 7 2 6292
telomeric heterochromatin 3.1815E-6 3 7 2 6292
nuclear heterochromatin 3.1815E-6 3 7 2 6292
heterochromatin 3.1815E-6 3 7 2 6292
chromatin remodeling complex 3.7798E-6 3 99 3 6292
telomere cap complex 8.329E-6 3 11 2 6292
nuclear telomere cap complex 8.329E-6 3 11 2 6292
nuclear chromosome, telomeric region 3.8264E-5 3 23 2 6292
chromosome, telomeric region 5.3064E-5 3 27 2 6292
nucleolar part 1.4938E-4 3 45 2 6292
protein-DNA complex 2.4051E-4 3 57 2 6292
nuclear chromatin 3.9536E-4 3 73 2 6292
chromatin 4.4E-4 3 77 2 6292
nuclear chromosome part 2.6674E-3 3 190 2 6292
nucleolus 3.2839E-3 3 211 2 6292
non-membrane-bounded organelle 3.5313E-3 3 959 3 6292
intracellular non-membrane-bounded organelle 3.5313E-3 3 959 3 6292
nuclear chromosome 3.8286E-3 3 228 2 6292
chromosomal part 4.1335E-3 3 237 2 6292
nuclear part 5.3751E-3 3 1103 3 6292
chromosome 5.5058E-3 3 274 2 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of gene expression, epigenetic 3.8967E-6 3 100 3 6292
gene silencing 3.8967E-6 3 100 3 6292
regulation of gene expression, epigenetic 3.8967E-6 3 100 3 6292
chromatin silencing 3.8967E-6 3 100 3 6292
loss of chromatin silencing involved in replicative cell aging 5.4528E-6 3 9 2 6292
progressive alteration of chromatin involved in replicative cell aging 6.8153E-6 3 10 2 6292
loss of chromatin silencing 6.8153E-6 3 10 2 6292
progressive alteration of chromatin involved in cell aging 8.329E-6 3 11 2 6292
positive regulation of gene expression, epigenetic 8.329E-6 3 11 2 6292
regulation of gene silencing 8.329E-6 3 11 2 6292
negative regulation of gene silencing 8.329E-6 3 11 2 6292
regulation of chromatin silencing 8.329E-6 3 11 2 6292
negative regulation of chromatin silencing 8.329E-6 3 11 2 6292
negative regulation of transcription, DNA-dependent 1.5247E-5 3 157 3 6292
negative regulation of RNA metabolic process 1.5543E-5 3 158 3 6292
negative regulation of transcription 1.7394E-5 3 164 3 6292
negative regulation of gene expression 1.7394E-5 3 164 3 6292
negative regulation of macromolecule biosynthetic process 2.1158E-5 3 175 3 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3035E-5 3 180 3 6292
negative regulation of nitrogen compound metabolic process 2.3035E-5 3 180 3 6292
chromatin silencing at rDNA 2.3152E-5 3 18 2 6292
negative regulation of biosynthetic process 2.6687E-5 3 189 3 6292
negative regulation of cellular biosynthetic process 2.6687E-5 3 189 3 6292
negative regulation of macromolecule metabolic process 2.7985E-5 3 192 3 6292
negative regulation of cellular metabolic process 3.6143E-5 3 209 3 6292
negative regulation of metabolic process 3.6667E-5 3 210 3 6292
double-strand break repair via nonhomologous end joining 4.5363E-5 3 25 2 6292
negative regulation of cellular process 6.2006E-5 3 250 3 6292
negative regulation of biological process 6.4274E-5 3 253 3 6292
non-recombinational repair 8.4748E-5 3 34 2 6292
replicative cell aging 1.0615E-4 3 38 2 6292
cell aging 1.7737E-4 3 49 2 6292
regulation of transcription, DNA-dependent 1.8274E-4 3 358 3 6292
regulation of RNA metabolic process 1.9053E-4 3 363 3 6292
aging 1.9226E-4 3 51 2 6292
regulation of transcription 2.2565E-4 3 384 3 6292
double-strand break repair 2.4051E-4 3 57 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.85E-4 3 415 3 6292
regulation of nitrogen compound metabolic process 2.8707E-4 3 416 3 6292
regulation of gene expression 3.5155E-4 3 445 3 6292
regulation of macromolecule biosynthetic process 3.7833E-4 3 456 3 6292
regulation of cellular biosynthetic process 4.1966E-4 3 472 3 6292
regulation of biosynthetic process 4.2234E-4 3 473 3 6292
regulation of macromolecule metabolic process 4.639E-4 3 488 3 6292
transcription, DNA-dependent 5.081E-4 3 503 3 6292
RNA biosynthetic process 5.2344E-4 3 508 3 6292
regulation of primary metabolic process 5.4224E-4 3 514 3 6292
regulation of cellular metabolic process 6.1504E-4 3 536 3 6292
regulation of metabolic process 6.5376E-4 3 547 3 6292
transcription 6.7188E-4 3 552 3 6292
positive regulation of transcription, DNA-dependent 7.8773E-4 3 103 2 6292
positive regulation of RNA metabolic process 8.5005E-4 3 107 2 6292
positive regulation of transcription 9.3124E-4 3 112 2 6292
positive regulation of gene expression 9.3124E-4 3 112 2 6292
nucleolus organization 9.5344E-4 3 2 1 6292
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0335E-3 3 118 2 6292
positive regulation of nitrogen compound metabolic process 1.0335E-3 3 118 2 6292
positive regulation of macromolecule biosynthetic process 1.0335E-3 3 118 2 6292
positive regulation of biosynthetic process 1.0866E-3 3 121 2 6292
positive regulation of cellular biosynthetic process 1.0866E-3 3 121 2 6292
positive regulation of macromolecule metabolic process 1.178E-3 3 126 2 6292
positive regulation of metabolic process 1.2346E-3 3 129 2 6292
positive regulation of cellular metabolic process 1.2346E-3 3 129 2 6292
positive regulation of cellular process 1.3717E-3 3 136 2 6292
positive regulation of biological process 1.3919E-3 3 137 2 6292
regulation of cellular process 2.0181E-3 3 796 3 6292
chromatin modification 2.089E-3 3 168 2 6292
regulation of biological process 2.2389E-3 3 824 3 6292
DNA repair 2.7234E-3 3 192 2 6292
chromatin organization 3.0416E-3 3 203 2 6292
RNA metabolic process 3.4763E-3 3 954 3 6292
response to DNA damage stimulus 4.0991E-3 3 236 2 6292
negative regulation of DNA replication 4.2857E-3 3 9 1 6292
organelle organization 5.734E-3 3 1127 3 6292
cellular response to stress 6.1581E-3 3 290 2 6292
chronological cell aging 6.6614E-3 3 14 1 6292
cellular macromolecule biosynthetic process 6.7003E-3 3 1187 3 6292
macromolecule biosynthetic process 6.7343E-3 3 1189 3 6292
regulation of DNA replication 7.136E-3 3 15 1 6292
biological regulation 7.1507E-3 3 1213 3 6292
developmental process 7.9899E-3 3 331 2 6292
gene expression 8.4626E-3 3 1283 3 6292
negative regulation of DNA metabolic process 9.9809E-3 3 21 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase activity (H3-K14 specific) 4.768E-4 3 1 1 6292
histone deacetylase activity (H3-K9 specific) 4.768E-4 3 1 1 6292
NAD-dependent histone deacetylase activity (H3-K9 specific) 4.768E-4 3 1 1 6292
NAD-dependent histone deacetylase activity (H3-K14 specific) 4.768E-4 3 1 1 6292
NAD-dependent histone deacetylase activity (H4-K16 specific) 4.768E-4 3 1 1 6292
structural constituent of chromatin 9.5344E-4 3 2 1 6292
rDNA binding 3.3344E-3 3 7 1 6292
NAD-dependent protein deacetylase activity 4.2857E-3 3 9 1 6292
NAD-dependent histone deacetylase activity 4.2857E-3 3 9 1 6292
histone binding 6.6614E-3 3 14 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle