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Any process that decreases the rate, frequency or extent of the process whereby new strands of DNA are synthesized in the mitochondrion. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that prevents the collapse of stalled replication forks. The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of initiation of DNA replication. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. Any cellular process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that modulates the frequency, rate or extent of DNA replication. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of DNA replication
Acc: GO:0008156
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.
Synonyms:
  • down-regulation of DNA replication
  • inhibition of DNA replication
  • DNA replication inhibitor
  • down regulation of DNA replication
  • downregulation of DNA replication
Proteins in PDR annotated with:
   This term: 47 [Search]
   Term or descendants: 139 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008156 - negative regulation of DNA replication (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle