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The process, arising in non-dividing cells as they age, that alters cellular metabolism and thus causes a decline in cell function. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Progression of the cell from its inception to the end of its lifespan. The inherent decline over time, from the optimal fertility and viability of early maturity, that may precede death and may be preceded by other indications, such as sterility. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation. The process by which changes in chromatin structure contributing to chronological cell aging occur in non-dividing cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: chronological cell aging
Acc: GO:0001300
Aspect: Biological Process
Desc: The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.
Synonyms:
  • chronological cell ageing
Proteins in PDR annotated with:
   This term: 22 [Search]
   Term or descendants: 38 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001300 - chronological cell aging (interactive image map)

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