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A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. null Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Progression of the cell from its inception to the end of its lifespan. The inherent decline over time, from the optimal fertility and viability of early maturity, that may precede death and may be preceded by other indications, such as sterility. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state. The chromatin modification process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cell aging
Acc: GO:0007569
Aspect: Biological Process
Desc: Progression of the cell from its inception to the end of its lifespan.
Synonyms:
  • cell ageing
  • cellular senescence
Proteins in PDR annotated with:
   This term: 60 [Search]
   Term or descendants: 164 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007569 - cell aging (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle