Protein Overview: Mdr49-PA

General Information:
Name(s) found:	Mdr49-PA / FBpp0086914 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24653245\|ref\|NP_523724.2\| multi drug resistance 49 [Drosophila melanogaster] [NCBI NR] gi\|21627300\|gb\|AAF58437.2\| multi drug resistance 49 [Drosophila melanogaster] [NCBI NR] gi\|201065723\|gb\|ACH92271.1\| FI05269p [Drosophila melanogaster] [NCBI NR] Multidrug resistance protein homolog 49 OS=Drosophila melanogaster GN=Mdr49 PE=2 SV=2 [Swiss-Prot] The gene Multi drug resistance 49 is referred to in FlyBase by the symbol Dmel\Mdr49 (CG3879, FBgn0004512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8827828..8833850. It has the cytological map location 49E1-49E4. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; multidrug transporter activity. There is experimental evidence that it is involved in the biological process</span>: response to hypoxia; germ cell migration. 7 alleles are reported. The phenotype of these alleles is annotated with: pole cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG3879-PA translation from_gene[CG3879 Mdr49 FBgn0004512] seq_release:3 mol_weight=142741 cds_boundaries:(2R:8,005,141..8,009,901[-]) aa_length:1302 transcript_info:[CG3879-RA seq_release:3] gene_info:[gene symbol:Mdr49 FBgn0004512 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta] CG3879-PA [Drosophila melanogaster]gi\|24653245\|ref\|NP_523724.2\| CG3879-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:complement(8827929..8828678,8828749..8829357,8829461..8829906,8830082..8831643,8832027..8832272,8832332..8832525,8832591..8832692); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Anno [fly-100309-contam.fasta] Multi drug resistance 49 CG3879-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG3879-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:complement(8827929..8828678,8828749..8829357,8829461..8829906,8830082..8831643,8832027..8832272,8832332..8832525,8832591..8832692); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:complement(8827929..8828678,8828749..8829357,8829461..8829906,8830082..8831643,8832027..8832272,8832332..8832525,8832591..8832692); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Multidrug resistance protein homolog 49 OS=Drosophila melanogaster GN=Mdr49 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:complement(8827929..8828678,8828749..8829357,8829461..8829906,8830082..8831643,8832027..8832272,8832332..8832525,8832591..8832692); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437,FlyMine:FBpp0086914,modMine:FBpp0086914; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:complement(join(12945086..12945187,12944827..12945020,12944522..12944767,12942577..12944138,12941956..12942401,12941244..12941852,12940424..12941173)); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437,FlyMine:FBpp0086914,modMine:FBpp0086914; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:complement(join(12945086..12945187,12944827..12945020,12944522..12944767,12942577..12944138,12941956..12942401,12941244..12941852,12940424..12941173)); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437,FlyMine:FBpp0086914,modMine:FBpp0086914; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0086914 type=protein; loc=2R:complement(join(12945086..12945187,12944827..12945020,12944522..12944767,12942577..12944138,12941956..12942401,12941244..12941852,12940424..12941173)); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437,FlyMine:FBpp0086914,modMine:FBpp0086914; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:complement(join(12945086..12945187,12944827..12945020,12944522..12944767,12942577..12944138,12941956..12942401,12941244..12941852,12940424..12941173)); ID=FBpp0086914; name=Mdr49-PA; parent=FBgn0004512,FBtr0087801; dbxref=FlyBase:FBpp0086914,FlyBase_Annotation_IDs:CG3879-PA,GB_protein:AAF58437.2,REFSEQ:NP_523724,GB_protein:AAF58437,UniProt/Swiss-Prot:Q00449,FlyMine:FBpp0086914,modMine:FBpp0086914; MD5=7c1931173116c6289bb5c6fd4c7bb9fb; length=1302; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1302 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [NAS] integral to membrane [IEA]
Biological Process:	drug transmembrane transport [NAS] drug transport [ISS] transmembrane transport [IEA] response to hypoxia [IEP][IMP] germ cell migration [IMP]
Molecular Function:	ATP binding [IEA] ATPase activity, coupled to transmembrane movement of substances [IEA] drug transmembrane transporter activity [ISS][NAS] ATPase activity, coupled [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKEESRLP QAGDFQLKEG SVVDATRKYS YFDLFRYSTR CERFLLVVSL LVATAASAFI  60
   61 PYFMIIYGEF TSLLVDRTVG VGTSSPAFAL PMFGGGQQLT NASKEENNQA IIDDATAFGI 120
  121 GSLVGSVAMF LLITLAIDLA NRIALNQIDR IRKLFLEAML RQDIAWYDTS SGSNFASKMT 180
  181 EDLDKLKEGI GEKIVIVVFL IMTFVIGIVS AFVYGWKLTL VVLSCVPFII AATSVVARLQ 240
  241 GSLAEKELKS YSDAANVVEE VFSGIRTVFA FSGQEKEKER FGKLLIPAEN TGRKKGLYSG 300
  301 MGNALSWLII YLCMALAIWY GVTLILDERD LPDRVYTPAV LVIVLFAVIM GAQNLGFASP 360
  361 HVEAIAVATA AGQTLFNIID RPSQVDPMDE KGNRPENTAG HIRFEGIRFR YPARPDVEIL 420
  421 KGLTVDVLPG QTVAFVGASG CGKSTLIQLM QRFYDPEAGS VKLDGRDLRT LNVGWLRSQI 480
  481 GVVGQEPVLF ATTIGENIRY GRPSATQADI EKAARAANCH DFITRLPKGY DTQVGEKGAQ 540
  541 ISGGQKQRIA IARALVRQPQ VLLLDEATSA LDPTSEKRVQ SALELASQGP TTLVVAHRLS 600
  601 TITNADKIVF LKDGVVAEQG THEELMERRG LYCELVSITQ RKEATEADEG AVAGRPLQKS 660
  661 QNLSDEETDD DEEDEEEDEE PELQTSGSSR DSGFRASTRR KRRSQRRKKK KDKEVVSKVS 720
  721 FTQLMKLNSP EWRFIVVGGI ASVMHGATFP LWGLFFGDFF GILSDGDDDV VRAEVLKISM 780
  781 IFVGIGLMAG LGNMLQTYMF TTAGVKMTTR LRKRAFGTII GQDIAYFDDE RNSVGALCSR 840
  841 LASDCSNVQG ATGARVGTML QAVATLVVGM VVGFVFSWQQ TLLTLVTLPL VCLSVYLEGR 900
  901 FIMKSAQKAK ASIEEASQVA VEAITNIRTV NGLCLERQVL DQYVQQIDRV DIACRRKVRF 960
  961 RGLVFALGQA APFLAYGISM YYGGILVAEE RMNYEDIIKV AEALIFGSWM LGQALAYAPN1020
 1021 VNDAILSAGR LMDLFKRTST QPNPPQSPYN TVEKSEGDIV YENVGFEYPT RKGTPILQGL1080
 1081 NLTIKKSTTV ALVGPSGSGK STCVQLLLRY YDPVSGSVNL SGVPSTEFPL DTLRSKLGLV1140
 1141 SQEPVLFDRT IAENIAYGNN FRDDVSMQEI IEAAKKSNIH NFISALPQGY DTRLGKTSQL1200
 1201 SGGQKQRIAI ARALVRNPKI LILDEATSAL DLESEKVVQQ ALDEARSGRT CLTIAHRLTT1260
 1261 VRNADLICVL KRGVVVEHGT HDELMALNKI YANLYLMQQV SG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..653]	PSI-BLAST	142.0	No description for 2hydA was found.
2	View Details	[654..1046]	FFAS03	4.44	No description for 2hydA was found.
3	View Details	[1047..1302]	PSI-BLAST	78.09691	Haemolysin B ATP-binding protein

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
lipid transporter activity	7.47642599298853	bayes_pls_golite062009
TAP binding	6.27051082044311	bayes_pls_golite062009
TAP1 binding	6.27051082044311	bayes_pls_golite062009
TAP2 binding	6.27051082044311	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	5.57844095962502	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	5.57813579764186	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	5.57813579764186	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	5.5689620139321	bayes_pls_golite062009
primary active transmembrane transporter activity	5.55992639965745	bayes_pls_golite062009
active transmembrane transporter activity	5.50005167063544	bayes_pls_golite062009
ATPase activity, coupled	4.98276715440477	bayes_pls_golite062009
heme transporter activity	4.82479229680991	bayes_pls_golite062009
peptide antigen-transporting ATPase activity	4.81855985294388	bayes_pls_golite062009
peptide transporter activity	4.7442815698413	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	4.71935767060308	bayes_pls_golite062009
ATPase activity	4.69795387297193	bayes_pls_golite062009
peptide-transporting ATPase activity	4.63590351019108	bayes_pls_golite062009
nucleoside-triphosphatase activity	4.45923622153365	bayes_pls_golite062009
pyrophosphatase activity	4.39781350157199	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	4.38133275795019	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4.38085303582726	bayes_pls_golite062009
cofactor transporter activity	4.34709589308604	bayes_pls_golite062009
transporter activity	3.71239480053329	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.57926427233638	bayes_pls_golite062009
ion transmembrane transporter activity	3.35436118751376	bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity	3.20894563245332	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16975154423199	bayes_pls_golite062009
hydrolase activity	3.14498892233323	bayes_pls_golite062009
transmembrane transporter activity	3.13960906549884	bayes_pls_golite062009
anion transmembrane transporter activity	3.13913638619234	bayes_pls_golite062009
substrate-specific transporter activity	3.1318898376276	bayes_pls_golite062009
cation transmembrane transporter activity	3.08390071341252	bayes_pls_golite062009
iron ion transmembrane transporter activity	3.05511942104215	bayes_pls_golite062009
ATP binding	3.01346604299372	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.00745742755195	bayes_pls_golite062009
drug transmembrane transporter activity	2.97119034312001	bayes_pls_golite062009
adenyl ribonucleotide binding	2.96271391116269	bayes_pls_golite062009
adenyl nucleotide binding	2.91131545957759	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	2.88795687640992	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.88476360771975	bayes_pls_golite062009
tapasin binding	2.81937502401698	bayes_pls_golite062009
purine ribonucleotide binding	2.70262534541085	bayes_pls_golite062009
ribonucleotide binding	2.70178191749524	bayes_pls_golite062009
amine-transporting ATPase activity	2.69529191205818	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.67957846350199	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	2.67815672695824	bayes_pls_golite062009
purine nucleotide binding	2.6583477492092	bayes_pls_golite062009
nucleotide binding	2.62374702628143	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.61311581579476	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	2.57684108006744	bayes_pls_golite062009
peptide antigen binding	2.5597979313877	bayes_pls_golite062009
sterol transporter activity	2.48473697371886	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.40292717311506	bayes_pls_golite062009
canalicular bile acid transmembrane transporter activity	2.33958437214304	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
binding	2.27048396817643	bayes_pls_golite062009
	2.20174656498665	bayes_pls_golite062009
vitamin transporter activity	2.1653565229854	bayes_pls_golite062009
phosphate transmembrane transporter activity	2.15147988861177	bayes_pls_golite062009
L-aspartate transmembrane transporter activity	2.05274761921715	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.82177108193332	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
amino acid transmembrane transporter activity	1.59627719545436	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.58971273330352	bayes_pls_golite062009
signal recognition particle binding	1.39788601145414	bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity	1.37836402136387	bayes_pls_golite062009
cation channel activity	1.33585529285301	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	1.28313088935613	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	1.28313088935613	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.23799860254751	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
potassium channel activity	1.17288958041707	bayes_pls_golite062009
homoaconitate hydratase activity	1.13752124535295	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	1.1220946941463	bayes_pls_golite062009
voltage-gated cation channel activity	1.00384984515681	bayes_pls_golite062009
thiamin transmembrane transporter activity	0.933872128802939	bayes_pls_golite062009
voltage-gated ion channel activity	0.889208591820696	bayes_pls_golite062009
motor activity	0.87979065815418	bayes_pls_golite062009
voltage-gated channel activity	0.871525745291603	bayes_pls_golite062009
	0.869999622006359	bayes_pls_golite062009
ion channel activity	0.848261056209476	bayes_pls_golite062009
GTPase activity	0.83849854735032	bayes_pls_golite062009
nucleic acid binding	0.806769185846999	bayes_pls_golite062009
channel activity	0.806331380134838	bayes_pls_golite062009
passive transmembrane transporter activity	0.806331380134838	bayes_pls_golite062009
substrate-specific channel activity	0.799997700906738	bayes_pls_golite062009
copper ion transmembrane transporter activity	0.798934081014025	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.767424210804186	bayes_pls_golite062009
bile acid transmembrane transporter activity	0.687612064139871	bayes_pls_golite062009
gated channel activity	0.650050847753837	bayes_pls_golite062009
cholesterol transporter activity	0.644421039250979	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
DNA binding	0.479412476059825	bayes_pls_golite062009
ribonucleoprotein binding	0.46620222872538	bayes_pls_golite062009
protein transmembrane transporter activity	0.46552249844591	bayes_pls_golite062009
catalytic activity	0.368034275052766	bayes_pls_golite062009
transcription regulator activity	0.312171320541728	bayes_pls_golite062009
signal transducer activity	0.286367085584159	bayes_pls_golite062009
molecular transducer activity	0.286367085584159	bayes_pls_golite062009
neutral amino acid transmembrane transporter activity	0.227570438294493	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.147644650870465	bayes_pls_golite062009
microtubule motor activity	0.11674780318211	bayes_pls_golite062009
sulfate transmembrane transporter activity	0.104477131120205	bayes_pls_golite062009
cation-transporting ATPase activity	0.0536898657672154	bayes_pls_golite062009
oligopeptide transporter activity	0.0268154844251251	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009

Term	Confidence	Notes
lipid transporter activity	6.95325922226092	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	5.4467861893359	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	5.44654566127945	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	5.44654566127945	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	5.43909190876515	bayes_pls_golite062009
primary active transmembrane transporter activity	5.4304944906989	bayes_pls_golite062009
active transmembrane transporter activity	5.38112407181712	bayes_pls_golite062009
ATPase activity, coupled	4.87869064889244	bayes_pls_golite062009
ATPase activity	4.60773943958528	bayes_pls_golite062009
nucleoside-triphosphatase activity	4.38591214726007	bayes_pls_golite062009
pyrophosphatase activity	4.32673473878039	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	4.31087891816858	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4.31037981322306	bayes_pls_golite062009
transporter activity	3.47953169973151	bayes_pls_golite062009
hydrolase activity	3.11706952898443	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.96171085039592	bayes_pls_golite062009
transmembrane transporter activity	2.94175800357966	bayes_pls_golite062009
substrate-specific transporter activity	2.90743799425416	bayes_pls_golite062009
ATP binding	2.83986218503994	bayes_pls_golite062009
adenyl ribonucleotide binding	2.79195527951815	bayes_pls_golite062009
adenyl nucleotide binding	2.74359323245512	bayes_pls_golite062009
purine ribonucleotide binding	2.55506944753783	bayes_pls_golite062009
ribonucleotide binding	2.55426312645972	bayes_pls_golite062009
purine nucleotide binding	2.51344800975739	bayes_pls_golite062009
nucleotide binding	2.48057252852174	bayes_pls_golite062009
binding	2.24416672769019	bayes_pls_golite062009
catalytic activity	0.372934161904337	bayes_pls_golite062009

Term	Confidence	Notes
P-P-bond-hydrolysis-driven transmembrane transporter activity	6.58863529263644	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	6.58067278719409	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	6.57974651657836	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	6.57922174989907	bayes_pls_golite062009
primary active transmembrane transporter activity	6.57807080367604	bayes_pls_golite062009
nucleoside-triphosphatase activity	6.48406410175216	bayes_pls_golite062009
active transmembrane transporter activity	6.48154954364331	bayes_pls_golite062009
pyrophosphatase activity	6.40467109535527	bayes_pls_golite062009
ATPase activity, coupled	6.40151534181487	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	6.38373914253885	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	6.38247436082206	bayes_pls_golite062009
ATPase activity	6.30019941712404	bayes_pls_golite062009
TAP binding	6.27051082044311	bayes_pls_golite062009
TAP1 binding	6.27051082044311	bayes_pls_golite062009
TAP2 binding	6.27051082044311	bayes_pls_golite062009
heme transporter activity	4.82479229680991	bayes_pls_golite062009
peptide antigen-transporting ATPase activity	4.81855985294388	bayes_pls_golite062009
peptide transporter activity	4.7442815698413	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	4.71935767060308	bayes_pls_golite062009
peptide-transporting ATPase activity	4.63590351019108	bayes_pls_golite062009
hydrolase activity	4.60957912556603	bayes_pls_golite062009
cofactor transporter activity	4.34709589308604	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.57926427233638	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.4837867129694	bayes_pls_golite062009
purine ribonucleotide binding	3.40690615950081	bayes_pls_golite062009
ribonucleotide binding	3.40594996232845	bayes_pls_golite062009
purine nucleotide binding	3.3669118613715	bayes_pls_golite062009
ion transmembrane transporter activity	3.35436118751376	bayes_pls_golite062009
nucleotide binding	3.33248266870364	bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity	3.20894563245332	bayes_pls_golite062009
ATP binding	3.17398570826788	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16975154423199	bayes_pls_golite062009
lipid transporter activity	3.14635082108971	bayes_pls_golite062009
anion transmembrane transporter activity	3.13913638619234	bayes_pls_golite062009
adenyl ribonucleotide binding	3.12628113185041	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
cation transmembrane transporter activity	3.08390071341252	bayes_pls_golite062009
adenyl nucleotide binding	3.0710107594224	bayes_pls_golite062009
iron ion transmembrane transporter activity	3.05511942104215	bayes_pls_golite062009
drug transmembrane transporter activity	2.97119034312001	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	2.88795687640992	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.88476360771975	bayes_pls_golite062009
tapasin binding	2.81937502401698	bayes_pls_golite062009
amine-transporting ATPase activity	2.69529191205818	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.67957846350199	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	2.67815672695824	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.61311581579476	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	2.57684108006744	bayes_pls_golite062009
peptide antigen binding	2.5597979313877	bayes_pls_golite062009
sterol transporter activity	2.48473697371886	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.40292717311506	bayes_pls_golite062009
canalicular bile acid transmembrane transporter activity	2.33958437214304	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
	2.20174656498665	bayes_pls_golite062009
vitamin transporter activity	2.1653565229854	bayes_pls_golite062009
phosphate transmembrane transporter activity	2.15147988861177	bayes_pls_golite062009
L-aspartate transmembrane transporter activity	2.05274761921715	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.82177108193332	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
amino acid transmembrane transporter activity	1.59627719545436	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.58971273330352	bayes_pls_golite062009
signal recognition particle binding	1.39788601145414	bayes_pls_golite062009
monocarboxylic acid transmembrane transporter activity	1.37836402136387	bayes_pls_golite062009
cation channel activity	1.33585529285301	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	1.28313088935613	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	1.28313088935613	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.23799860254751	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
potassium channel activity	1.17288958041707	bayes_pls_golite062009
homoaconitate hydratase activity	1.13752124535295	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	1.1220946941463	bayes_pls_golite062009
voltage-gated cation channel activity	1.00384984515681	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
thiamin transmembrane transporter activity	0.933872128802939	bayes_pls_golite062009
voltage-gated ion channel activity	0.889208591820696	bayes_pls_golite062009
motor activity	0.87979065815418	bayes_pls_golite062009
voltage-gated channel activity	0.871525745291603	bayes_pls_golite062009
	0.869999622006359	bayes_pls_golite062009
ion channel activity	0.848261056209476	bayes_pls_golite062009
GTPase activity	0.83849854735032	bayes_pls_golite062009
nucleic acid binding	0.806769185846999	bayes_pls_golite062009
channel activity	0.806331380134838	bayes_pls_golite062009
passive transmembrane transporter activity	0.806331380134838	bayes_pls_golite062009
substrate-specific channel activity	0.799997700906738	bayes_pls_golite062009
copper ion transmembrane transporter activity	0.798934081014025	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.767424210804186	bayes_pls_golite062009
bile acid transmembrane transporter activity	0.687612064139871	bayes_pls_golite062009
gated channel activity	0.650050847753837	bayes_pls_golite062009
cholesterol transporter activity	0.644421039250979	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
DNA binding	0.479412476059825	bayes_pls_golite062009
ribonucleoprotein binding	0.46620222872538	bayes_pls_golite062009
protein transmembrane transporter activity	0.46552249844591	bayes_pls_golite062009
transcription regulator activity	0.312171320541728	bayes_pls_golite062009
signal transducer activity	0.286367085584159	bayes_pls_golite062009
molecular transducer activity	0.286367085584159	bayes_pls_golite062009
neutral amino acid transmembrane transporter activity	0.227570438294493	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.147644650870465	bayes_pls_golite062009
microtubule motor activity	0.11674780318211	bayes_pls_golite062009
sulfate transmembrane transporter activity	0.104477131120205	bayes_pls_golite062009
cation-transporting ATPase activity	0.0536898657672154	bayes_pls_golite062009
oligopeptide transporter activity	0.0268154844251251	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.00571427458217011	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Protein Overview: Mdr49-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: