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The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism. The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target. The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form. Programmed cell death of an errant germ line cell that are outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue. The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. The orderly movement of a cell from one site to another, often during the development of a multicellular organism or multicellular structure. Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: germ cell migration
Acc: GO:0008354
Aspect: Biological Process
Desc: The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
Synonyms:
  • germ-cell migration
  • primordial germ cell migration
Proteins in PDR annotated with:
   This term: 79 [Search]
   Term or descendants: 97 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008354 - germ cell migration (interactive image map)
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