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Protein Overview: TAF8

General Information:
Name(s) found: TAF8 / YML114C [SGD]
Description(s) found:
Found 25 descriptions.
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  • TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 510 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    transcription factor TFIID complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: transcription from RNA polymerase II promoter [IPILink to PubMed article]
    Molecular Function: RNA polymerase II transcription factor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSKTSESGT GTQSTIVQLR NLPDLTEISH LEIDAPVVEI LKKTVLFQLN SLNICISNFA  60
   61 LDELVNLVTV QMDGMFRNLH NLTLLQRRSQ ASQADLKLLL REFNLDAPSL YQQFQASEFI 120
  121 KSKHSTEYEK LMSWSSLAAL PHNEEDEEDE LNNIEEQQNE INVLLPPSNP LEKQIPSWLP 180
  181 NFPPDHTYKF TPEFNHPITD LKTIKKEIVK ESQESEKALL NLNKSLSHIS SASNTPQPPG 240
  241 LDDEDAIEQQ LEIWGNALEE RKPTITEKSF NENNIEQYAK YRVELARERV TKFEVNQLKR 300
  301 TKNPFLKISE TLYLPESPHQ SHKTIQKTIE LQFRKSMTLF MHNLPKVQKL KKEKIRMAKE 360
  361 ERAKSLKRRQ EELISQRTKR EQDEGHDLEL LLNNEHARDA ADDTTTPNAL NNSTIVINTN 420
  421 AEDEDDDINL FGILGSSEDE NEMSSMPAEN LVAESEPPTM TAQDTTNTTP VAHNTTNIDA 480
  481 TTSHSPHSTP NENAPTSPPA DIATDHDITM

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) TAF1 TAF14 TAF2 TAF8
    View Details Krogan NJ, et al. (2006) ESC1 ROX1 TAF2 TAF8
    View Details Gavin AC, et al. (2006) TAF2 TAF8
    View Details Gavin AC, et al. (2002) ADA2 ADH1 CLU1 FUN19 GCN5 HEM13 KAP114 KAP123 MED4 MES1 MNN4 MOT1 MYO1 NGG1 NOP1 PFK2 PSK1 PTC1 PUF6 RPB2 RPN9 RPO21 RPT5 RVB2 SGF29 SGF73 SIN3 SIN4 SPT15 SPT20 SPT7 SPT8 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBF1 TEF4 VAS1 VPS1
    View Details Qiu et al. (2008) HFI1 MED6 SGF73 SPT20 TAF1 TAF10 TAF11 TAF12 TAF13 TAF14 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TFB5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TAF8 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] MSA 10.015996 View MSA. No confident structure predictions are available.
    2 View Details [265..510] deduced N/A No confident structure predictions are available.
    3 View Details [192..510] FFAS03 1.26 No description for 2i1jA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle