Protein Overview: RPL38

General Information:
Name(s) found:	RPL38 / YLR325C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|662127\|gb\|AAB64512.1\| Ylr325cp [Saccharomyces cerevisiae] [NCBI NR] gi\|6323357\|ref\|NP_013429.1\| Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein; Rpl38p [Saccharomyces cerevisiae] [NCBI NR] gi\|1350739\|sp\|P49167.1\|RL38_YEAST RecName: Full=60S ribosomal protein L38 [NCBI NR] pir\|\|S53402 ribosomal protein L38.e, cytosolic - yeast (Saccharomyces cerevisiae) [NCBI NR] 60S ribosomal protein L38 OS=Saccharomyces cerevisiae GN=RPL38 PE=1 SV=1 [Swiss-Prot] RPL38 60S large subunit ribosomal protein [mips] Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein [SGD] RPL38, Chr XII from 781143-781379, reverse complement [yeast_orfs2] Chr XII from 781143-781379, reverse complement [yeastorf3.fasta] Chr XII from 781379-781143, reverse complement [yeastorf5.fasta] (P49167) 60S ribosomal protein L38 [4932.FASTACCERV.txt] RPL38 SGDID:S0004317, Chr XII from 781379-781143, reverse complement, Verified ORF [yeastflysequest.fasta] Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein [Saccharomyces cerevisiae]gi\|662127\|gb\|AAB64512.1\| Ylr325cp [Saccharomyces cerevisiae]gi\|1078076\|pir\|\|S53402 ribosomal protein L38.e, cytosolic - yeast ( [nrdb_11152004_Chlamydomonas] RPL38 SGDID:S000004317, Chr XII from 781379-781143, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Ylr325cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein; Rpl38p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] 60S ribosomal protein L38 [nr-271106-contam.fasta] [chemostatdb.fasta] 60S ribosomal protein L38 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPL38 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] RPL38 SGDID:S000004317, Chr XII from 781379-781143, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" [yeast-030211-contam.fasta] RPL38 SGDID:S000004317, Chr XII from 781379-781143, Genome Release 64-2-1, reverse complement, Verified ORF, "Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog" [20141208_orf_trans.fasta] YLR325C SGDID:S000004317, Chr XII from 781379-781143, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	78 amino acids
Gene Ontology:
Cellular Component:	ribonucleoprotein complex [IEA] cytoplasm [IEA] cytosolic large ribosomal subunit [TAS] ribosome [IEA] intracellular [IEA]
Biological Process:	translation [TAS]
Molecular Function:	structural constituent of ribosome [TAS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MAREITDIKQ FLELTRRADV KTATVKINKK LNKAGKPFRQ TKFKVRGSSS LYTLVINDAG 60 61 KAKKLIQSLP PTLKVNRL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		BUD20 NOG1 NOG2 NUG1 RPL13B RPL16A RPL25 RPL28 RPL36A RPL36B RPL38 RSA4
View Details	(MIPS) Mewes HW, et al. (2004)		RPL10 RPL11A RPL11B RPL12B, RPL12A RPL13A RPL13B RPL14A RPL14B RPL15A RPL15B RPL16A RPL16B RPL17A RPL17B RPL18A, RPL18B RPL19B, RPL19A RPL1A, RPL1B RPL20A RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL25 RPL26A RPL26B RPL27A RPL27B RPL28 RPL29 RPL2A, RPL2B RPL3 RPL30 RPL31A RPL31B RPL32 RPL33A RPL33B RPL34A RPL34B RPL35A, RPL35B RPL36A RPL36B RPL37A RPL37B RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL4A RPL4B RPL5 RPL6A RPL6B RPL7A RPL7B RPL8A RPL8B RPL9A RPL9B RPP0 RPP1A RPP1B RPP2A RPP2B
View Details	Krogan NJ, et al. (2006)		IRC8 LSM12 RPL38 YLL032C
View Details	Gavin AC, et al. (2006)		PSH1 RPL38
View Details	Qiu et al. (2008)		ASC1 ATG27 BUD20 FYV12 HMS2 KRR1 NAT3 RKI1 RPL10 RPL11A RPL11B RPL12B, RPL12A RPL13A RPL13B RPL14A RPL14B RPL15A RPL15B RPL16A RPL16B RPL17A RPL17B RPL18A, RPL18B RPL19B, RPL19A RPL1A, RPL1B RPL20A RPL20B RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL25 RPL26A RPL26B RPL27A RPL27B RPL28 RPL29 RPL2A, RPL2B RPL3 RPL30 RPL31A RPL31B RPL32 RPL33A RPL33B RPL34A RPL34B RPL35A, RPL35B RPL36A RPL36B RPL37A RPL37B RPL38 RPL39 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL4A RPL4B RPL5 RPL6A RPL6B RPL7A RPL7B RPL8A RPL8B RPL9A RPL9B RPP0 RPP1A RPP1B RPP2A RPP2B RPS0A RPS0B RPS10A RPS10B RPS11A, RPS11B RPS12 RPS13 RPS14A RPS14B RPS15 RPS16B, RPS16A RPS17A RPS17B RPS18B, RPS18A RPS19A RPS19B RPS1A RPS1B RPS2 RPS20 RPS21A RPS21B RPS22A RPS22B RPS23B, RPS23A RPS24A, RPS24B RPS25A RPS25B RPS26A RPS26B RPS27A RPS27B RPS28A RPS28B RPS29A RPS29B RPS3 RPS30B, RPS30A RPS31 RPS4B, RPS4A RPS5 RPS6A, RPS6B RPS7A RPS7B RPS8B, RPS8A RPS9A RPS9B RRP5 SFT1 STM1 TEF1, TEF2 TOS4 TSR1 TSR2 YDL133W YML6 YPL199C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	HSL7	No Comments	McCusker D, et al (2007)
View Run	TOR2	No Comments	Reinke A, et al. (2004)
View Run	SEC10	No Comments	De Craene, J., et al. (2006)
View Run	RPA135	his-HA tag on RPA135	Schneider, DA, et al. (2006)
View Run	DAD1	Dam1-765 complex purified from yeast with Dad1-TAP	Shimogawa MM, et al. (2006)
View Run	BOI1	Sample boi 1 with ha tag from october 2005	McCusker D, et al (2007)
View Run	BOI1	Sample boi1 with gst from october 2005	McCusker D, et al (2007)
View Run	BOI1	Sample bob1 (2nd set) from october 2005	McCusker D, et al (2007)
View Run	VAM3	hx23: mixture in detergent (control) Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex	Hao Xu, et al. (2010)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	LSM4	RPL38	1	Unpublished Fields Lab Data
View Screen	FCF2	RPL38	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	RPL38	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..78]	Pfam	54.60206	No description for PF01781.9 was found. Confident ab initio structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle