YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Yak1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AHP1
  • cytoplasm
  • response to oxidative stress
  • response to metal ion
  • thioredoxin peroxidase activity
  • CDC39
  • nucleus
  • cytoplasm
  • CCR4-NOT core complex
  • negative regulation of transcription from RNA polymerase II promoter
  • response to pheromone involved in conjugation with cellular fusion
  • pseudohyphal growth
  • nuclear-transcribed mRNA poly(A) tail shortening
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • 3'-5'-exoribonuclease activity
  • DCS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • cytoplasmic mRNA processing body
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • m7G(5')pppN diphosphatase activity
  • DCS2
  • cytoplasm
  • cytoplasmic mRNA processing body
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • m7G(5')pppN diphosphatase activity
  • GDB1
  • cytoplasm
  • mitochondrion
  • glycogen catabolic process
  • amylo-alpha-1,6-glucosidase activity
  • 4-alpha-glucanotransferase activity
  • RAD50
  • nucleus
  • mitochondrion
  • Mre11 complex
  • meiotic DNA double-strand break processing
  • double-strand break repair via break-induced replication
  • telomere maintenance
  • telomere maintenance via recombination
  • double-strand break repair via nonhomologous end joining
  • meiosis
  • meiotic DNA double-strand break formation
  • ATPase activity
  • adenylate kinase activity
  • protein binding
  • telomeric DNA binding
  • double-stranded DNA binding
  • TSA2
  • cytoplasm
  • response to oxidative stress
  • thioredoxin peroxidase activity
  • peroxiredoxin activity
  • UBP15
  • cytoplasm
  • protein deubiquitination
  • ubiquitin-specific protease activity
  • UBR1
  • proteasome complex
  • protein polyubiquitination
  • protein monoubiquitination
  • ubiquitin-protein ligase activity
  • VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
  • GTPase activity
  • YAK1
  • nucleus
  • cytoplasm
  • protein amino acid phosphorylation
  • protein kinase activity
  • YLR241W
  • cellular_component
  • biological_process
  • molecular_function
  • YPL247C
  • nucleus
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytoplasmic mRNA processing body 4.0759E-4 13 15 2 6292
    Mre11 complex 6.1865E-3 13 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1.959E-5 13 27 3 6292
    nuclear-transcribed mRNA catabolic process 5.5762E-5 13 38 3 6292
    macromolecule catabolic process 2.0324E-4 13 294 5 6292
    deadenylation-dependent decapping of nuclear-transcribed mRNA 2.145E-4 13 11 2 6292
    mRNA catabolic process 3.3372E-4 13 69 3 6292
    RNA catabolic process 5.1647E-4 13 80 3 6292
    cellular macromolecule catabolic process 1.627E-3 13 265 4 6292
    catabolic process 2.253E-3 13 496 5 6292
    meiotic DNA double-strand break processing 6.1865E-3 13 3 1 6292
    cellular catabolic process 8.2693E-3 13 415 4 6292
    mRNA metabolic process 8.5088E-3 13 213 3 6292
    response to oxidative stress 8.5513E-3 13 69 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    m7G(5')pppN diphosphatase activity 3.9273E-5 13 5 2 6292
    peroxiredoxin activity 1.4073E-4 13 9 2 6292
    thioredoxin peroxidase activity 1.4073E-4 13 9 2 6292
    catalytic activity 2.6944E-4 13 2150 11 6292
    oxidoreductase activity, acting on peroxide as acceptor 7.3325E-4 13 20 2 6292
    peroxidase activity 7.3325E-4 13 20 2 6292
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9.7297E-4 13 23 2 6292
    hydrolase activity 1.0061E-3 13 911 7 6292
    antioxidant activity 1.151E-3 13 25 2 6292
    glycogen debranching enzyme activity 2.0661E-3 13 1 1 6292
    amylo-alpha-1,6-glucosidase activity 2.0661E-3 13 1 1 6292
    4-alpha-glucanotransferase activity 2.0661E-3 13 1 1 6292
    hydrolase activity, acting on acid anhydrides 4.646E-3 13 353 4 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.646E-3 13 353 4 6292
    pyrophosphatase activity 4.646E-3 13 353 4 6292
    adenylate kinase activity 8.2408E-3 13 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle