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Protein Overview: YPL247C

General Information:
Name(s) found: YPL247C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPFHNGNKR SSISFGSSQR QPYNKNNYLS GTNGPSSAAQ DQGRGPSPFG MSGNTTNGGN  60
   61 SKRNSGCDLS ATYYASRSPM YSPLDFSPPV FSPNHSQLQQ ARGYAANIPV VSNLMNPSMA 120
  121 SVCEYQSHYP LFGLDWSADD YVCLGSYKED SRNKLQVLHS NDLLSWESVV DADVVYPVSK 180
  181 IQWVPSQLYP RKLATCSDSL RIWSVSPEER QFQEQINLSL CKYNRQHPAN PAAADDMKVI 240
  241 GTFPPITSFD WNTVDTNLII SSSIDTTCIV WDLQSSHYVK TQLIAHDSEV FDVRFLTKST 300
  301 QLFASCGGDG SVRVFDLRSL AHSTIIYEPP SSSVSGATAG TITPSSKGSD ALLRLEPSPY 360
  361 DPNVLATFAA DSNKIIILDM RNPESPILNL QGHGSSVNGI KWHPTKRNVL LSCGDDCQVL 420
  421 YWDLNSSFME INAAGSKSPS IHGTSLEDPD GDTEMTDGGA GSGLNEDPLS LNNNSKQVCK 480
  481 TLETPNMMYA NKTQEINNIA WRPQRGDWFG CVSGKKFQNV RVL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALT1 HSP60 YPL247C
    View Details Ho Y, et al. (2002) AHP1 CDC39 DCS1 DCS2 DNM1 GDB1 RAD50 TSA2 UBP15 UBR1 VPS1 YAK1 YLR241W YPL247C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YOR203W YPL247C 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPL247C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] PSI-BLAST 21.69897 Groucho/tle1, C-terminal domain
    2 View Details [123..523] PSI-BLAST 63.512579 beta1-subunit of the signal-transducing G protein heterotrimer


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle