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The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: deadenylation-dependent decapping of nuclear-transcribed mRNA
Acc: GO:0000290
Aspect: Biological Process
Desc: Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
Synonyms:
  • deadenylylation-dependent decapping
  • deadenylation-dependent decapping of nuclear mRNA
Proteins in PDR annotated with:
   This term: 29 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA (interactive image map)

YRC Informatics Platform - Version 3.0
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