YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Gavin A.C. et al. (2002) Abstract Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 2002 Jan 10;415(6868):141-7.
Notes:	From the published set of protein complexes.
Complex Size:	16 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
CKA1	protein kinase CK2 complex	G2/M transition of mitotic cell cycle G1/S transition of mitotic cell cycle flocculation via cell wall protein-carbohydrate interaction protein amino acid phosphorylation response to DNA damage stimulus regulation of transcription from RNA polymerase III promoter regulation of transcription from RNA polymerase I promoter cellular ion homeostasis	protein kinase CK2 activity
CKA2	protein kinase CK2 complex	G2/M transition of mitotic cell cycle G1/S transition of mitotic cell cycle flocculation via cell wall protein-carbohydrate interaction protein amino acid phosphorylation response to DNA damage stimulus regulation of transcription from RNA polymerase III promoter regulation of transcription from RNA polymerase I promoter cellular ion homeostasis	protein kinase CK2 activity
CKB1	protein kinase CK2 complex	G2/M transition of mitotic cell cycle G1/S transition of mitotic cell cycle flocculation via cell wall protein-carbohydrate interaction protein amino acid phosphorylation response to DNA damage stimulus regulation of transcription from RNA polymerase III promoter regulation of transcription from RNA polymerase I promoter cellular ion homeostasis	protein kinase CK2 regulator activity
DBP2	nucleus cytoplasm mitochondrion nuclear outer membrane	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	RNA helicase activity
MRPS28	mitochondrion mitochondrial small ribosomal subunit	ribosomal small subunit assembly translation	RNA binding structural constituent of ribosome
NUP120	nuclear pore	mRNA export from nucleus rRNA export from nucleus nuclear pore organization snRNP protein import into nucleus mRNA-binding (hnRNP) protein import into nucleus snRNA export from nucleus chromosome localization tRNA export from nucleus NLS-bearing substrate import into nucleus DNA metabolic process protein export from nucleus ribosomal protein import into nucleus	structural molecule activity
NUP145	nuclear pore	tRNA splicing, via endonucleolytic cleavage and ligation protein export from nucleus ribosomal protein import into nucleus mRNA export from nucleus rRNA export from nucleus nuclear pore organization snRNP protein import into nucleus mRNA-binding (hnRNP) protein import into nucleus snRNA export from nucleus protein import into nucleus chromosome localization tRNA export from nucleus NLS-bearing substrate import into nucleus	RNA binding structural molecule activity
NUP84	nuclear pore	DNA metabolic process protein export from nucleus response to DNA damage stimulus ribosomal protein import into nucleus mRNA export from nucleus rRNA export from nucleus nuclear envelope organization nuclear pore organization snRNP protein import into nucleus mRNA-binding (hnRNP) protein import into nucleus snRNA export from nucleus chromosome localization tRNA export from nucleus NLS-bearing substrate import into nucleus	structural molecule activity
NUP85	nuclear pore	mRNA export from nucleus rRNA export from nucleus nuclear envelope organization nuclear pore organization snRNP protein import into nucleus mRNA-binding (hnRNP) protein import into nucleus snRNA export from nucleus tRNA export from nucleus NLS-bearing substrate import into nucleus protein export from nucleus ribosomal protein import into nucleus	structural molecule activity
RPP2B	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translational elongation translation	structural constituent of ribosome
SEC13	cytoplasm extrinsic to membrane COPII vesicle coat nuclear pore	ER to Golgi vesicle-mediated transport membrane budding nuclear pore organization ER-associated protein catabolic process	structural molecule activity
SEC16	endoplasmic reticulum membrane extrinsic to membrane COPII vesicle coat	vesicle coating vesicle-mediated transport autophagy	structural molecule activity
SEC23	cytoplasm COPII vesicle coat	ER to Golgi vesicle-mediated transport autophagy ER-associated protein catabolic process	GTPase activator activity
SEC31	COPII vesicle coat	ER to Golgi vesicle-mediated transport	structural molecule activity
SEH1	nuclear pore	mRNA export from nucleus rRNA export from nucleus nuclear pore organization snRNP protein import into nucleus mRNA-binding (hnRNP) protein import into nucleus snRNA export from nucleus tRNA export from nucleus NLS-bearing substrate import into nucleus protein export from nucleus ribosomal protein import into nucleus	structural molecule activity
STM1	cytoplasm nuclear telomere cap complex	anti-apoptosis telomere maintenance	DNA binding telomeric DNA binding

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
pore complex	1.7807E-9	16	52	6	6292
nuclear pore	1.7807E-9	16	52	6	6292
COPII vesicle coat	1.9408E-9	16	8	4	6292
ER to Golgi transport vesicle membrane	1.9408E-9	16	8	4	6292
endomembrane system	5.2196E-9	16	398	10	6292
macromolecular complex	1.9232E-8	16	1635	15	6292
transport vesicle membrane	3.7443E-8	16	15	4	6292
protein kinase CK2 complex	5.3897E-8	16	4	3	6292
nuclear envelope	2.5599E-7	16	199	7	6292
membrane part	6.917E-7	16	662	10	6292
ER to Golgi transport vesicle	8.4224E-7	16	31	4	6292
protein complex	1.0222E-6	16	1137	12	6292
vesicle coat	1.2357E-6	16	34	4	6292
coated vesicle membrane	1.393E-6	16	35	4	6292
cytoplasmic vesicle membrane	1.393E-6	16	35	4	6292
vesicle membrane	1.393E-6	16	35	4	6292
membrane coat	1.9548E-6	16	38	4	6292
coated membrane	1.9548E-6	16	38	4	6292
cytoplasmic vesicle part	2.1749E-6	16	39	4	6292
transport vesicle	3.9036E-6	16	45	4	6292
integral to membrane	2.3754E-5	16	255	6	6292
intrinsic to membrane	2.7716E-5	16	262	6	6292
coated vesicle	4.5419E-5	16	83	4	6292
membrane-bounded vesicle	1.2293E-4	16	107	4	6292
cytoplasmic vesicle	1.2293E-4	16	107	4	6292
cytoplasmic membrane-bounded vesicle	1.2293E-4	16	107	4	6292
envelope	1.2407E-4	16	505	7	6292
organelle envelope	1.2407E-4	16	505	7	6292
vesicle	1.3689E-4	16	110	4	6292
membrane	1.5763E-4	16	1198	10	6292
intracellular organelle part	3.0309E-4	16	2282	13	6292
organelle part	3.0309E-4	16	2282	13	6292
nuclear part	2.9591E-3	16	1103	8	6292
extrinsic to membrane	7.1889E-3	16	51	2	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
nuclear pore organization	3.4053E-11	16	28	6	6292
ribosomal protein import into nucleus	1.7449E-9	16	23	5	6292
snRNP protein import into nucleus	1.7449E-9	16	23	5	6292
NLS-bearing substrate import into nucleus	1.7449E-9	16	23	5	6292
snRNA transport	1.7449E-9	16	23	5	6292
snRNA export from nucleus	1.7449E-9	16	23	5	6292
mRNA-binding (hnRNP) protein import into nucleus	2.747E-9	16	25	5	6292
nucleus organization	2.8243E-9	16	56	6	6292
rRNA transport	4.1619E-9	16	27	5	6292
rRNA export from nucleus	4.1619E-9	16	27	5	6292
tRNA transport	5.0592E-9	16	28	5	6292
tRNA export from nucleus	5.0592E-9	16	28	5	6292
protein export from nucleus	1.0306E-8	16	32	5	6292
chromosome localization	5.3897E-8	16	4	3	6292
regulation of transcription from RNA polymerase I promoter	5.3897E-8	16	4	3	6292
protein localization in nucleus	8.5603E-8	16	48	5	6292
protein import into nucleus	8.5603E-8	16	48	5	6292
nuclear import	8.5603E-8	16	48	5	6292
regulation of transcription from RNA polymerase III promoter	4.6941E-7	16	7	3	6292
mRNA transport	5.0607E-7	16	68	5	6292
mRNA export from nucleus	5.0607E-7	16	68	5	6292
RNA export from nucleus	1.1467E-6	16	80	5	6292
RNA transport	1.2204E-6	16	81	5	6292
nucleic acid transport	1.2204E-6	16	81	5	6292
establishment of RNA localization	1.2204E-6	16	81	5	6292
cellular macromolecular complex subunit organization	1.5367E-6	16	259	7	6292
flocculation via cell wall protein-carbohydrate interaction	1.6019E-6	16	10	3	6292
flocculation	2.1992E-6	16	11	3	6292
RNA localization	2.3047E-6	16	92	5	6292
nucleobase, nucleoside, nucleotide and nucleic acid transport	2.8478E-6	16	96	5	6292
nuclear export	4.0368E-6	16	103	5	6292
protein import	5.1025E-6	16	108	5	6292
nuclear transport	1.2684E-5	16	130	5	6292
nucleocytoplasmic transport	1.2684E-5	16	130	5	6292
macromolecular complex subunit organization	1.3081E-5	16	357	7	6292
intracellular transport	2.3074E-5	16	553	8	6292
protein localization in organelle	2.4641E-5	16	149	5	6292
establishment of localization in cell	4.1501E-5	16	599	8	6292
G2/M transition of mitotic cell cycle	4.7361E-5	16	29	3	6292
transcription from RNA polymerase I promoter	5.2542E-5	16	30	3	6292
membrane budding	6.0363E-5	16	5	2	6292
cellular localization	6.9546E-5	16	643	8	6292
transcription from RNA polymerase III promoter	1.0783E-4	16	38	3	6292
nuclear envelope organization	1.2639E-4	16	7	2	6292
ribosome biogenesis	1.3245E-4	16	346	6	6292
ribonucleoprotein complex biogenesis	2.037E-4	16	374	6	6292
protein targeting	2.17E-4	16	235	5	6292
transport	2.4145E-4	16	997	9	6292
G1/S transition of mitotic cell cycle	2.459E-4	16	50	3	6292
establishment of localization	2.6325E-4	16	1008	9	6292
intracellular protein transport	3.1792E-4	16	255	5	6292
localization	3.9043E-4	16	1060	9	6292
protein transport	4.0756E-4	16	269	5	6292
establishment of protein localization	4.2179E-4	16	271	5	6292
cellular protein localization	4.4385E-4	16	274	5	6292
cellular macromolecule localization	5.2377E-4	16	284	5	6292
organelle organization	6.2793E-4	16	1127	9	6292
protein localization	7.0528E-4	16	303	5	6292
ER to Golgi vesicle-mediated transport	1.0951E-3	16	83	3	6292
organelle localization	1.1736E-3	16	85	3	6292
cellular membrane organization	1.2859E-3	16	198	4	6292
membrane organization	1.2859E-3	16	198	4	6292
interphase of mitotic cell cycle	1.7195E-3	16	97	3	6292
interphase	1.7195E-3	16	97	3	6292
cellular macromolecule metabolic process	1.8653E-3	16	2285	12	6292
protein amino acid phosphorylation	2.0433E-3	16	103	3	6292
macromolecule localization	2.3826E-3	16	397	5	6292
macromolecule metabolic process	2.4586E-3	16	2349	12	6292
response to DNA damage stimulus	2.459E-3	16	236	4	6292
negative regulation of programmed cell death	2.5429E-3	16	1	1	6292
negative regulation of cell death	2.5429E-3	16	1	1	6292
anti-apoptosis	2.5429E-3	16	1	1	6292
negative regulation of apoptosis	2.5429E-3	16	1	1	6292
cellular chemical homeostasis	3.0859E-3	16	119	3	6292
cellular ion homeostasis	3.0859E-3	16	119	3	6292
cellular homeostasis	3.1601E-3	16	120	3	6292
chemical homeostasis	3.3894E-3	16	123	3	6292
ion homeostasis	3.3894E-3	16	123	3	6292
cellular process	3.565E-3	16	4426	16	6292
ER-associated protein catabolic process	4.2529E-3	16	39	2	6292
autophagy	4.9198E-3	16	42	2	6292
cellular response to stress	5.1802E-3	16	290	4	6292
multi-organism process	5.1809E-3	16	143	3	6292
cellular component biogenesis	5.3341E-3	16	694	6	6292
vesicle organization	5.8791E-3	16	46	2	6292
cellular metabolic process	7.176E-3	16	3033	13	6292
cellular component organization	7.7019E-3	16	1582	9	6292
Golgi vesicle transport	8.1059E-3	16	168	3	6292
vesicle-mediated transport	9.0817E-3	16	340	4	6292
phosphorylation	9.6489E-3	16	179	3	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
structural molecule activity	1.0852E-9	16	339	10	6292
protein kinase CK2 activity	6.0632E-6	16	2	2	6292
obsolete_molecular_function	6.382E-4	16	69	3	6292
protein kinase CK2 regulator activity	5.0798E-3	16	2	1	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis