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Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that modulates the occurrence or rate of cell death by apoptosis. A process which directly inhibits any of the steps required for cell death by apoptosis. Any process that activates or increases the frequency, rate or extent of anti-apoptosis. Any process that modulates the frequency, rate or extent of anti-apoptosis. Any process that stops, prevents or reduces the frequency, rate or extent of anti-apoptosis.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: anti-apoptosis
Acc: GO:0006916
Aspect: Biological Process
Desc: A process which directly inhibits any of the steps required for cell death by apoptosis.
Synonyms:
  • apoptosis inhibitor activity
Proteins in PDR annotated with:
   This term: 310 [Search]
   Term or descendants: 406 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006916 - anti-apoptosis (interactive image map)
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