YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes:	MIPS hand-curated complex set. MIPS complex ID: 230.20.20
Complex Size:	16 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
ADA2	SLIK (SAGA-like) complex Ada2/Gcn5/Ada3 transcription activator complex SAGA complex	chromatin modification histone acetylation	transcription coactivator activity
GCN5	SLIK (SAGA-like) complex Ada2/Gcn5/Ada3 transcription activator complex SAGA complex	chromatin modification histone acetylation	histone acetyltransferase activity transcription coactivator activity
HFI1	SLIK (SAGA-like) complex Ada2/Gcn5/Ada3 transcription activator complex SAGA complex	chromatin modification telomere maintenance transcription from RNA polymerase II promoter histone acetylation	transcription cofactor activity transcription coactivator activity
NGG1	SLIK (SAGA-like) complex Ada2/Gcn5/Ada3 transcription activator complex SAGA complex	chromatin modification response to drug histone acetylation	transcription cofactor activity
SGF29	SAGA complex	histone acetylation	molecular_function
SGF73	SLIK (SAGA-like) complex SAGA complex	chromatin modification histone acetylation	histone acetyltransferase activity structural molecule activity
SPT20	SLIK (SAGA-like) complex SAGA complex	chromatin modification histone acetylation	transcription cofactor activity
SPT3	SLIK (SAGA-like) complex SAGA complex	chromatin modification ascospore formation conjugation with cellular fusion pseudohyphal growth histone acetylation invasive growth in response to glucose limitation	transcription cofactor activity
SPT7	SLIK (SAGA-like) complex mitochondrion SAGA complex	chromatin modification protein complex assembly conjugation with cellular fusion histone acetylation	structural molecule activity
SPT8	nucleus SAGA complex	negative regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter	transcription cofactor activity TATA-binding protein binding
TAF10	transcription factor TFIID complex SLIK (SAGA-like) complex SAGA complex	chromatin modification protein amino acid acetylation histone acetylation chromatin organization regulation of transcription involved in G1 phase of mitotic cell cycle transcription initiation from RNA polymerase II promoter	general RNA polymerase II transcription factor activity
TAF12	transcription factor TFIID complex SLIK (SAGA-like) complex SAGA complex	chromatin modification protein amino acid acetylation histone acetylation chromatin organization regulation of transcription involved in G1 phase of mitotic cell cycle transcription initiation from RNA polymerase II promoter	general RNA polymerase II transcription factor activity
TAF5	transcription factor TFIID complex SLIK (SAGA-like) complex SAGA complex	chromatin modification protein amino acid acetylation histone acetylation chromatin organization regulation of transcription involved in G1 phase of mitotic cell cycle transcription initiation from RNA polymerase II promoter	general RNA polymerase II transcription factor activity
TAF6	transcription factor TFIID complex SLIK (SAGA-like) complex SAGA complex	chromatin modification protein amino acid acetylation histone acetylation chromatin organization regulation of transcription involved in G1 phase of mitotic cell cycle transcription initiation from RNA polymerase II promoter	general RNA polymerase II transcription factor activity
TAF9	transcription factor TFIID complex SLIK (SAGA-like) complex SAGA complex	chromatin modification protein amino acid acetylation histone acetylation chromatin organization regulation of transcription involved in G1 phase of mitotic cell cycle transcription initiation from RNA polymerase II promoter	general RNA polymerase II transcription factor activity
TRA1	NuA4 histone acetyltransferase complex SLIK (SAGA-like) complex SAGA complex histone acetyltransferase complex	DNA repair histone acetylation regulation of transcription from RNA polymerase II promoter	histone acetyltransferase activity

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
SAGA complex	2.637E-43	16	22	16	6292
SAGA-type complex	8.6643E-43	16	23	16	6292
SLIK (SAGA-like) complex	8.3513E-39	16	16	14	6292
histone acetyltransferase complex	1.4727E-36	16	44	16	6292
nucleoplasm part	1.7258E-23	16	245	16	6292
nucleoplasm	5.9149E-23	16	264	16	6292
nuclear lumen	4.0631E-19	16	453	16	6292
organelle lumen	1.823E-16	16	660	16	6292
intracellular organelle lumen	1.823E-16	16	660	16	6292
membrane-enclosed lumen	4.7232E-16	16	700	16	6292
nuclear part	7.2679E-13	16	1103	16	6292
protein complex	1.1852E-12	16	1137	16	6292
Ada2/Gcn5/Ada3 transcription activator complex	1.3927E-10	16	5	4	6292
transcription factor TFIID complex	1.5755E-10	16	15	5	6292
macromolecular complex	4.0924E-10	16	1635	16	6292
nucleus	1.444E-8	16	2041	16	6292
organelle part	8.6662E-8	16	2282	16	6292
intracellular organelle part	8.6662E-8	16	2282	16	6292
DNA-directed RNA polymerase II, holoenzyme	1.8874E-7	16	56	5	6292
transcription factor complex	6.2931E-7	16	71	5	6292
membrane-bounded organelle	2.7361E-4	16	3771	16	6292
intracellular membrane-bounded organelle	2.7361E-4	16	3771	16	6292
intracellular organelle	9.2974E-4	16	4070	16	6292
organelle	9.334E-4	16	4071	16	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
histone acetylation	1.2313E-34	16	36	15	6292
protein amino acid acetylation	1.13E-32	16	46	15	6292
protein amino acid acylation	8.7923E-31	16	59	15	6292
covalent chromatin modification	6.9625E-28	16	88	15	6292
histone modification	6.9625E-28	16	88	15	6292
chromatin modification	2.0871E-23	16	168	15	6292
chromatin organization	3.9759E-22	16	203	15	6292
post-translational protein modification	2.3297E-18	16	357	15	6292
protein modification process	3.7686E-16	16	499	15	6292
chromosome organization	1.8816E-15	16	555	15	6292
macromolecule modification	2.7409E-15	16	569	15	6292
cellular protein metabolic process	3.7773E-11	16	1074	15	6292
organelle organization	7.7426E-11	16	1127	15	6292
protein metabolic process	8.7162E-11	16	1136	15	6292
regulation of transcription involved in G1 phase of mitotic cell cycle	1.0519E-10	16	14	5	6292
G1 phase	4.1619E-9	16	27	5	6292
G1 phase of mitotic cell cycle	4.1619E-9	16	27	5	6292
cellular component organization	1.1829E-8	16	1582	15	6292
transcription initiation from RNA polymerase II promoter	7.6798E-8	16	47	5	6292
cellular macromolecule metabolic process	8.851E-8	16	2285	16	6292
macromolecule metabolic process	1.379E-7	16	2349	16	6292
transcription initiation	2.2574E-7	16	58	5	6292
transcription from RNA polymerase II promoter	5.2568E-7	16	335	8	6292
regulation of transcription from RNA polymerase II promoter	6.4796E-7	16	228	7	6292
protein complex biogenesis	1.3251E-6	16	155	6	6292
protein complex assembly	1.3251E-6	16	155	6	6292
interphase of mitotic cell cycle	2.9982E-6	16	97	5	6292
interphase	2.9982E-6	16	97	5	6292
primary metabolic process	3.9666E-6	16	2896	16	6292
cellular metabolic process	8.3256E-6	16	3033	16	6292
transcription, DNA-dependent	1.1429E-5	16	503	8	6292
RNA biosynthetic process	1.2302E-5	16	508	8	6292
regulation of transcription, DNA-dependent	1.3324E-5	16	358	7	6292
regulation of RNA metabolic process	1.4599E-5	16	363	7	6292
metabolic process	1.5832E-5	16	3157	16	6292
regulation of transcription	2.1121E-5	16	384	7	6292
transcription	2.2768E-5	16	552	8	6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	3.506E-5	16	415	7	6292
regulation of nitrogen compound metabolic process	3.5614E-5	16	416	7	6292
macromolecular complex assembly	4.1235E-5	16	281	6	6292
regulation of gene expression	5.5118E-5	16	445	7	6292
regulation of macromolecule biosynthetic process	6.4521E-5	16	456	7	6292
regulation of cellular biosynthetic process	8.054E-5	16	472	7	6292
regulation of biosynthetic process	8.1641E-5	16	473	7	6292
regulation of macromolecule metabolic process	9.9716E-5	16	488	7	6292
regulation of primary metabolic process	1.3883E-4	16	514	7	6292
macromolecular complex subunit organization	1.5755E-4	16	357	6	6292
regulation of cellular metabolic process	1.8107E-4	16	536	7	6292
regulation of metabolic process	2.0586E-4	16	547	7	6292
cellular component assembly	2.3891E-4	16	385	6	6292
mitotic cell cycle	3.1792E-4	16	255	5	6292
biological regulation	1.1018E-3	16	1213	9	6292
RNA metabolic process	1.1201E-3	16	954	8	6292
cell cycle phase	1.8715E-3	16	376	5	6292
regulation of cellular process	2.0519E-3	16	796	7	6292
regulation of biological process	2.5166E-3	16	824	7	6292
cellular process	3.565E-3	16	4426	16	6292
cellular macromolecule biosynthetic process	4.773E-3	16	1187	8	6292
macromolecule biosynthetic process	4.8251E-3	16	1189	8	6292
cellular component biogenesis	5.3341E-3	16	694	6	6292
cell cycle process	5.9543E-3	16	490	5	6292
gene expression	7.8351E-3	16	1283	8	6292
cell cycle	7.9806E-3	16	525	5	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
transcription regulator activity	7.4214E-13	16	339	12	6292
transcription cofactor activity	2.6504E-12	16	40	7	6292
transcription factor binding	4.5638E-12	16	43	7	6292
general RNA polymerase II transcription factor activity	3.7233E-7	16	64	5	6292
histone acetyltransferase activity	8.9795E-6	16	17	3	6292
lysine N-acetyltransferase activity	8.9795E-6	16	17	3	6292
RNA polymerase II transcription factor activity	1.2684E-5	16	130	5	6292
transcription coactivator activity	1.7454E-5	16	21	3	6292
N-acetyltransferase activity	7.028E-5	16	33	3	6292
N-acyltransferase activity	1.0783E-4	16	38	3	6292
acetyltransferase activity	2.459E-4	16	50	3	6292
protein binding	4.1565E-4	16	612	7	6292
transcription activator activity	4.4387E-4	16	61	3	6292
transferase activity, transferring acyl groups other than amino-acyl groups	1.476E-3	16	92	3	6292
acyltransferase activity	1.476E-3	16	92	3	6292
transferase activity, transferring acyl groups	2.279E-3	16	107	3	6292
TATA-binding protein binding	5.0798E-3	16	2	1	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis